Reperfusion Physiology
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Role of mast cells in ischemic acute renal failure / Participação de mastocitos na lesão renal induzida por isquemia/reperfusão
Renal ischemia is the main cause of acute renal failure in both native and transplanted kidneys. Ischemia/reperfusion lesion includes changes in renal hemodynamic, endothelial and tubular cell lesion, and inflammatory process, resulting in endothelial cell activation, increased adhesion of endothelial cells and leukocytes, migration of circulating cells to d
Publicado em: 2007
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2. Avaliação da resposta inflamatoria pos-isquemia e reperfusão pulmonar normotermica em ratos submetidos a exercicio fisico regular / Evaluation of the inflammatory response in normothermic pulmonary ischemia and reperfusion in mice undergone to physical regular exercise
Objetivos: A proposta deste estudo foi avaliar os efeitos do treinamento físico na resposta inflamatória (permeabilidade vascular e influxo neutrofílico) após isquemia-reperfusão pulmonar (IRP) em ratos. Considerando que o treinamento físico tem propriedades protetoras em determinadas doenças cardiovasculares, hipotetizamos que animais submetidos a tr
Publicado em: 2006
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3. Intracellular free calcium concentration measured with 19F NMR spectroscopy in intact ferret hearts.
Changes in the intracellular free Ca2+ concentration, [Ca2+]i, mediate excitation-contraction coupling in the heart and contribute to cellular injury during ischemia and reperfusion. To study these processes directly, we measured [Ca2+]i in perfused ferret (Mustela putorius furo) hearts using 19F NMR spectroscopy to detect the 5,5'-difluoro derivative of the
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4. Noninvasive real-time imaging of apoptosis
Strict coordination of proliferation and programmed cell death (apoptosis) is essential for normal physiology. An imbalance in these two opposing processes results in various diseases including AIDS, neurodegenerative disorders, myelodysplastic syndromes, ischemia/reperfusion injury, cancer, autoimmune disease, among others. Objective and quantitative noninv
National Academy of Sciences.
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5. Science review: Redox and oxygen-sensitive transcription factors in the regulation of oxidant-mediated lung injury: role for hypoxia-inducible factor-1α
A progressive rise of oxidative stress due to altered reduction–oxidation (redox) homeostasis appears to be one of the hallmarks of the processes that regulate gene transcription in physiology and pathophysiology. Reactive oxygen species and reactive nitrogen species serve as signaling messengers for the evolution and perpetuation of the inflammatory proce
BioMed Central.
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6. Role of transforming growth factor-beta in maintenance of function of cultured neonatal cardiac myocytes. Autocrine action and reversal of damaging effects of interleukin-1.
The three isoforms of transforming growth factor-beta (TGF-beta) have previously been implicated in embryonic development of the heart as well as in repair of myocardial damage after ischemia/reperfusion injury. TGF-beta 1 has also been localized intracellularly to both mitochondria and contractile filaments of cardiac myocytes, although its role in these st
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7. Anticipating anticipation: pursuing identification of cardiomyocyte circadian clock function
Diurnal rhythms in myocardial physiology (e.g., metabolism, contractile function) and pathophyiology (e.g., sudden cardiac death) are well establish and have classically been ascribed to time-of-day-dependent alterations in the neurohumoral milieu. Existence of an intramyocellular circadian clock has recently been exposed. Circadian clocks enable the cell to
American Physiological Society.
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8. Sphingosine-1-phosphate receptor signalling in the heart
The five known members of the sphingosine-1-phosphate (S1P) receptor family exhibit diverse tissue expression profiles and couple to distinct G-protein-mediated signalling pathways. S1P1, S1P2, and S1P3 receptors are all present in the heart, but the ratio of these subtypes differs for various cardiac cells. The goal of this review is to summarize data conce
Oxford University Press.