Recombinant Viruses
Mostrando 1-12 de 1588 artigos, teses e dissertações.
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1. Description of a human Bocavirus recombinant strain in the Americas
Human bocaviruses (HBoV) are mainly associated with respiratory and gastroenteric infections. These viruses belong to the family Parvoviridae, genus Bocaparvovirus and are classified in four subtypes (HBoV1-4). Recombination and point mutation have been described as basis of parvovirus evolution. In this study three viral sequences were obtained from positiv
Mem. Inst. Oswaldo Cruz. Publicado em: 21/10/2019
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2. Construction and characterization of a recombinant yellow fever virus stably expressing Gaussia luciferase
ABSTRACT Yellow fever is an arthropod-borne viral disease that still poses high public health concerns, despite the availability of an effective vaccine. The development of recombinant viruses is of utmost importance for several types of studies, such as those aimed to dissect virus-host interactions and to search for novel antiviral strategies. Moreover, re
An. Acad. Bras. Ciênc.. Publicado em: 20/07/2017
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3. Papillomaviruses: a systematic review
Abstract In the last decades, a group of viruses has received great attention due to its relationship with cancer development and its wide distribution throughout the vertebrates: the papillomaviruses. In this article, we aim to review some of the most relevant reports concerning the use of bovines as an experimental model for studies related to papillomavir
Genet. Mol. Biol.. Publicado em: 16/02/2017
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4. Use of homologous recombination in yeast to create chimeric bovine viral diarrhea virus cDNA clones
Abstract The open reading frame of a Brazilian bovine viral diarrhea virus (BVDV) strain, IBSP4ncp, was recombined with the untranslated regions of the reference NADL strain by homologous recombination in Saccharomyces cerevisiae, resulting in chimeric full-length cDNA clones of BVDV (chi-NADL/IBSP4ncp#2 and chi-NADL/IBSP4ncp#3). The recombinant clones were
Braz. J. Microbiol.. Publicado em: 2016-12
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5. A glycoprotein E gene-deleted bovine herpesvirus 1 as a candidate vaccine strain
A bovine herpesvirus 1 (BoHV-1) defective in glycoprotein E (gE) was constructed from a Brazilian genital BoHV-1 isolate, by replacing the full gE coding region with the green fluorescent protein (GFP) gene for selection. Upon co-transfection of MDBK cells with genomic viral DNA plus the GFP-bearing gE-deletion plasmid, three fluorescent recombinant clones w
Braz J Med Biol Res. Publicado em: 21/07/2015
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6. A Saint Louis encephalitis and Rocio virus serosurvey in Brazilian horses
Introduction Arboviruses are an important public health problem in Brazil, in especially flaviviruses, including the Saint Louis encephalitis virus (SLEV) and the Rocio virus (ROCV), are especially problematic. These viruses are transmitted to humans or other vertebrates through arthropod bites and may cause diseases with clinical manifestations that range
Rev. Soc. Bras. Med. Trop.. Publicado em: 2014-08
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7. First report of recombination in Potato yellow vein virus (PYVV) in Colombia
Potato yellow vein virus (PYVV) is currently one of the most important viruses that infects potatoes in Colombia and other Andean countries, causing losses in the production of tubers ranging from 25% to 50%. This study analyzed the genetic variability of different viral isolates collected in the department of Nariño, Colombia, through bioinformatics analys
Trop. plant pathol.. Publicado em: 2014-06
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8. Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi
Sandflies (Diptera: Psychodidae) are important disease vectors of parasites of the genus Leishmania, as well as bacteria and viruses. Following studies of the midgut transcriptome of Phlebotomus papatasi, the principal vector of Leishmania major, two non-classical Kazal-type serine proteinase inhibitors were identified (PpKzl1 and PpKzl2). Analyses of expres
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-09
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9. Serologic survey of hantavirus in a rural population from the northern State of Mato Grosso, Brazil
INTRODUCTION: Hantavirus is a genus of ribonucleic acid (RNA) viruses included in the family Bunyaviridae. Hantaviruses are rodent-borne zoonoses that, in the last 18 years, became an emergent public health problem in the Americas, causing a severe cardiopulmonary syndrome. This disease has no specific treatment and has a high case fatality. The transmission
Rev. Soc. Bras. Med. Trop.. Publicado em: 2013-01
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10. Desenvolvimento de vetores não virais para entrega gênica baseados na cadeia leve de dineína Rp3 = : Development of non viral vectors for gene delivery based on dynein light chain Rp3 / Development of non viral vectors for gene delivery based on dynein light chain Rp3
Gene delivery is a promising technique with great medical potential that consists in the introduction of exogenous nucleic acids, and can be applied for gene therapy as well as DNA vaccination. However, its use is still limited by the lack of an ideal delivery vector, which is both safe and efficient. Although much more effective, viral vectors still raise s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/07/2012
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11. Determinantes virais envolvidos na adaptabilidade diferencial de dois begomovírus em tomateiro e Nicotiana benthamiana / Viral determinants involves in the differential adaptation of two begomovirus in tomato and Nicotiana benthamiana
Begomoviruses (family Geminiviridae) have a genome composed of a one or two components of circular, single-stranded DNA and infect dicotyledoneous plants. Symptoms induced by the begomovirus Tomato yellow spot virus (ToYSV) in tomato and Nicotiana benthamiana are more severe and appear earlier compared to those induced by Tomato rugose mosaic virus (ToRMV).
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/12/2011
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12. Caracterização biológica e molecular de recombinantes naturais de HIV-1. / Biological and molecular characterization of HIV-1 natural recombinants.
Recombination during reverse transcription is an important factor promoting HIV-1 diversity and adaptive change, allowing advantageous mutations arising on different genomes to undergo linkage in the same progeny recombinant genome more frequently than what would be expected under random mutation alone. In Brazil, several recombinant viruses were reported, a
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 09/05/2011