Recombinant Human Collagen
Mostrando 1-12 de 66 artigos, teses e dissertações.
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1. Collagen sponge and rhBMP-2 improve socket healing in rats treated with zoledronic acid
Abstract The aim of the present study was to evaluate the possible use of a commercial absorbed collagen sponge and bone morphogenetic protein (BMP) for the prevention of bisphosphonate-related osteonecrosis of the jaw (BRONJ) in rats. Twenty rats received intraperitoneal injections of 0.1-mg/kg of zoledronic acid three times a week for eight weeks before th
Braz. oral res.. Publicado em: 07/12/2017
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2. Changes in cardiac aldosterone and its synthase in rats with chronic heart failure: an intervention study of long-term treatment with recombinant human brain natriuretic peptide
The physiological mechanisms involved in isoproterenol (ISO)-induced chronic heart failure (CHF) are not fully understood. In this study, we investigated local changes in cardiac aldosterone and its synthase in rats with ISO-induced CHF, and evaluated the effects of treatment with recombinant human brain natriuretic peptide (rhBNP). Sprague-Dawley rats were
Braz J Med Biol Res. Publicado em: 11/07/2014
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3. Is combined therapy more effective than growth hormone or hyperbaric oxygen alone in the healing of left ischemic and non-ischemic colonic anastomoses?
OBJECTIVE: Our aim was to investigate the effects of growth hormone (GH), hyperbaric oxygen and combined therapy on normal and ischemic colonic anastomoses in rats. METHODS: Eighty male Wistar rats were divided into eight groups (n = 10). In the first four groups, non-ischemic colonic anastomosis was performed, whereas in the remaining four groups, is
Clinics. Publicado em: 2013-11
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4. Engenharia de tecidos com células-tronco de dentes decíduos e scaffolds injetáveis e a formação de polpa dental funcional / Stem cells from exfoliated deciduous teeth and self-assembling nanofiber and recombinant human collagen I scaffolds allows for the engineering of a functional dental pulp
A translação da regeneração pulpar com células tronco para a clinica requerirá o uso de scaffolds injetáveis. O objetivo foi estudar o comportamento de células tronco obtidas de dentes decíduos exfoliados (SHED) injetados em canais radiculares de pré-molares humanos com ápice aberto com scaffold de colágeno recombinante humano tipo I (rhC-I) e a
Publicado em: 2010
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5. Expression, purification and characterization of surface proteins from Leptospira interrogans. / Expressão, purificação e caracterização de proteínas de superfície de Leptospira interrogans.
The whole-genome sequences of L. interrogans serovar Copenhageni and the bioinformatic tools allow us to choose fifteen genes encoding for conserved hypothetical proteins predicted to be exported to the membrane. The chosen genes were amplified by PCR from six predominant pathogenic serovars, the DNA cloned in an E. coli vector, the recombinant proteins expr
Publicado em: 2009
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6. CHARACTERIZATION OF E METILISOCITRATO isocitrate Lias Lias The fungal human pathogen Paracoccidioides brasiliensis / CARACTERIZAÇÃO DA ISOCITRATO LIASE E METILISOCITRATO LIASE DO FUNGO PATOGÊNICO HUMANO Paracoccidioides brasiliensis
Paracoccidioides brasiliensis, a thermodimorphic fungus, is the causative agent of paracoccidioidomycosis (PCM), a prevalent systemic mycosis in Latin America. Pathogenicity appears to be intimately related to the dimorphic transition from the hyphal to the yeast form, which is induced by a shift from environmental temperature to the temperature of the mamma
Publicado em: 2009
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7. CARACTERIZAÇÃO DA ISOCITRATO LIASE E METILISOCITRATO LIASE DO FUNGO PATOGÊNICO HUMANO Paracoccidioides brasiliensis / CHARACTERIZATION OF E METILISOCITRATO isocitrate Lias Lias The fungal human pathogen Paracoccidioides brasiliensis
Paracoccidioides brasiliensis, a thermodimorphic fungus, is the causative agent of paracoccidioidomycosis (PCM), a prevalent systemic mycosis in Latin America. Pathogenicity appears to be intimately related to the dimorphic transition from the hyphal to the yeast form, which is induced by a shift from environmental temperature to the temperature of the mamma
Publicado em: 2009
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8. Pulpal and periapical response of dogs teeth after pulpotomy and use of bone morphogenetic protein (rHuBMP-7). Histopathologic and radiographic study. / Resposta pulpar e periapical de dentes de cães após pulpotomia e utilização da proteína óssea morfogenética (rHuBMP-7). Estudo histopatológico e radiográfico
O objetivo deste estudo foi a avaliação histopatológica e radiográfica da resposta pulpar e periapical de dentes de cães após pulpotomia e utilização da Proteína Morfogenética Óssea Recombinante Humana 7. Foram utilizados 60 dentes (120 raízes) de 6 cães, divididos em 8 grupos, nos períodos experimentais de 7 dias (Grupos I, II, III, IV) e 70 d
Publicado em: 2006
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9. Cloning, characterization, and functional studies of a nonintegrin platelet receptor for type I collagen.
A cDNA (1.6 kb) encoding a platelet protein receptor that binds type I collagen has been isolated from a human bone marrow cDNA library by using a degenerate oligonucleotide probe derived from the amino acid sequence of a CNBr fragment of the purified receptor. Computer search revealed that this cDNA represents the coding sequence of a unique protein. Using
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10. Human type I procollagen genes are located on different chromosomes.
A recombinant plasmid containing sequences complementary to human pro-alpha l(I) collagen mRNA was used for the chromosomal assignment of the pro-alpha l(I) collagen gene. Restriction endonuclease analysis of DNA from mouse-human and Chinese hamster-human somatic cell hybrids revealed cosegregation with human chromosome 17. Hybrids containing derivative chro
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11. Rescue of type I collagen-deficient phenotype by retroviral-vector-mediated transfer of human pro alpha 1(I) collagen gene into Mov-13 cells.
A full-length cDNA clone corresponding to the human pro alpha 1(I) collagen gene was isolated and inserted into a retrovirus vector. Cell lines were obtained which produced recombinant viruses transducing the collagen cDNA (HUC virus). To test whether the transduced cDNA was functional, Mov-13 mouse cells were infected with the virus. These cells do not prod
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12. Selective inhibition of human diploid fibroblast collagen synthesis by interferons.
The effects of alpha- and gamma-interferons (IFNs) on collagen production by confluent human diploid fibroblasts in culture were examined. It was found that partially purified alpha-IFNs and affinity purified gamma-IFNs caused greater than 50% inhibition of collagen synthesis by these cells independently of their effect on cell proliferation. Recombinant alp