Rational Drug Use
Mostrando 1-12 de 49 artigos, teses e dissertações.
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1. Revisão dos dispositivos legais e normativos internacionais e nacionais sobre gestão de medicamentos e de seus resíduos
Resumo Este trabalho apresenta uma revisão descritiva de leis e normas adotadas pelos países da Europa, das Américas e Austrália sobre gestão de medicamentos e de seus resíduos. Esta revisão integra pontos relevantes de documentos oficiais das agências reguladoras desses países, bem como de trabalhos científicos importantes. Todos os países pesqui
Ciênc. saúde coletiva. Publicado em: 05/08/2019
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2. Medication consumption in a Brazilian area covered by the Family Health Strategy: Prevalence and associated factors
Resumo Objetivo: O objetivo deste estudo foi determinar a prevalência e os fatores associados ao consumo de medicamentos em usuários cadastrados em uma Estratégia de Saúde da Família (ESF) de Rondonópolis, Mato Grosso, Brasil. Método: A população foi constituída por todos os moradores adultos da área de abrangência da ESF. Para análise estatí
Esc. Anna Nery. Publicado em: 25/04/2019
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3. Antimicrobial susceptibility profile of historical and recent Brazilian pig isolates of Pasteurella multocida
RESUMO: Pasteurella (P.) multocida é o agente da pasteurelose pneumônica em suínos, a qual é comumente associada com o estágio final da pneumonia enzoótica suína ou complexo das doenças respiratórias dos suínos. Apesar de ser uma das doenças mais comuns e importantes na suinocultura, dados sobre suscetibilidade antimicrobiana de isolados de P. mul
Pesq. Vet. Bras.. Publicado em: 2019-02
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4. Pharmacists in dispensing drugs (PharmDisp): protocol for a clinical trial to test the effectiveness of distance education in training pharmacists for dispensing drugs
ABSTRACT Dispensing drug is a moment in which the pharmacist is able to analyze pharmacotherapy and contribute to its rational use. However, research has shown that some pharmacists lack adequate knowledge to perform this service. This study aims to describe a research protocol for a clinical trial to test the effectiveness of a distance learning program to
Braz. J. Pharm. Sci.. Publicado em: 14/05/2018
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5. Increase of 10% in the Rate of Adverse Drug Reactions for Each Drug Administered in Hospitalized Patients
OBJECTIVE: To assess the risk factors, incidence and severity of adverse drug reactions in in-patients. METHODS: This prospective study evaluated 472 patients treated at a teaching hospital in Brazil between 2010 and 2013 by five medical specialties: Internal Medicine, General Surgery, Geriatrics, Neurology, and Clinical Immunology and Allergy. The followi
Clinics. Publicado em: 08/02/2018
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6. Pharmacovigilance of patients with multiple myeloma being treated with bortezomib and/or thalidomide
In order to evaluate the main adverse effects of drug protocols using bortezomib and/or thalidomide for the treatment of multiple myeloma, we conducted a prospective study. Data were collected through interviews, clinical observation, and from hospital records. A total of 59 patients were included. There was a predominance of females, 36 (61%) vs 23 (39%) ma
Braz J Med Biol Res. Publicado em: 31/05/2016
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7. Resistance patterns, prevalence, and predictors of fluoroquinolones resistance in multidrug resistant tuberculosis patients
Abstract Background Fluoroquinolones are the backbone of multidrug resistant tuberculosis treatment regimens. Despite the high burden of multidrug resistant tuberculosis in the country, little is known about drug resistance patterns, prevalence, and predictors of fluoroquinolones resistance among multidrug resistant tuberculosis patients from Pakistan. Obj
Braz J Infect Dis. Publicado em: 2016-02
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8. Descriptores globales y locales de la reactividad para el diseño de nuevos fármacos anticancerosos basados en cis-platino(II)
Density functional theory was used to investigate the global and local reactivity of some cis-platinum(II) complexes including anticancer drugs, such as cisplatin and carboplatin. Calculated equilibrium geometries at mPW1PW/LANL2DZ* are in close agreement with their available X-ray data. We develop three new local reactivity descriptors: atomic descriptor of
Quím. Nova. Publicado em: 2013
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9. Desenvolvimento de um algoritmo para identificação e caracterização de cavidades em regiões específicas de estruturas tridimensionais de proteínas / Development of an algorithm to identify and characterize cavities in specific regions of three-dimensional structures of proteins.
The identification and characterization of geometrical and physical-chemical properties in protein vacant spaces aggregates important information for steering rational drug designing and functional characterization of binding and catalytic sites. Therefore, several softwares have been develop during the past two decades in order to perform such characterizat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/05/2011
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10. A propaganda de medicamentos em escola de medicina do Sul do Brasil / Drug advertisement in a medicine school in the Southern of Brazil
Este trabalho apresenta um estudo qualiquantitativo sobre propaganda de medicamentos em escola de medicina do Sul do Brasil. Participaram da pesquisa estudantes de medicina, professores médicos e pacientes dos ambulatórios da escola, totalizando 1.231 entrevistas. A pesquisa qualitativa foi realizada por meio de técnica de grupo focal, e a quantitativa pe
Publicado em: 2011
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11. Estudos de modelagem molecular e relação estrutura-atividade da acetilcolinesterase e inibidores em Mal de Alzheimer / Molecular modeling studies and structure-activity relationships of acetylcholinesterase inhibitors in Alzheimers disease.
Alzheimers disease is the leading cause of dementia in the elderly. The progression of symptoms is associated with structural changes in cholinergic synapses in specific brain regions and consequentely to decrease the potential of cholinergic neurotransmission. Thus, the increased capacity of cholinergic neurotransmission is the fundamental mechanism of the
Publicado em: 2011
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12. Uso de anti-hipertensivos e hipoglicemiantes por idosos, em Belo Horizonte, MG
Introduction: Changes in the epidemiological profile, coupled with demographic transition, the improvement in quality of life and technological advances, are characteristics of the aging phenomenon of Brazilian population, where are predominant the cardiovascular diseases. Among the main risk factors are arterial hypertension (HA) and diabetes mellitus (DM).
Publicado em: 2010