Radiosensitivity
Mostrando 1-12 de 104 artigos, teses e dissertações.
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1. Comparison of radiosensitivity response to acute and chronic gamma irradiation in colored wheat
Abstract We aimed to investigate the biological responses induced by acute and chronic gamma irradiation in colored wheat seeds rich in natural antioxidants. After acute and chronic irradiation, the phenotypic effects on plant growth, germination rate, seedling height, and root length were examined, and the biochemical changes were investigated by analyzing
Genet. Mol. Biol.. Publicado em: 28/06/2018
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2. Morphophysiological and biochemical alterations in Ricinus communis L. seeds submitted to cobalt60 gamma radiation
ABSTRACT This study aimed to evaluate the radiosensitivity of castor bean seeds after applications of different doses of Cobalt60 gamma radiation. Seeds were pre-soaked for 24 hours in distilled water and then irradiated with 50, 100, 150, and 200 Gy, except the control. Sowing was performed in trays, which contained soil as substrate and were maintained in
An. Acad. Bras. Ciênc.. Publicado em: 31/07/2017
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3. Active caspase-3 expression levels as bioindicator of individual radiosensitivity
ABSTRACT Several molecules and events involved in cell response to radiation-induced damage have been investigated towards a personalized radiotherapy. Considering the importance of active caspase-3 in the proteolytic cascade that ensures radiation-induced apoptosis execution, this research was designed to evaluate the expression levels of this protein as a
An. Acad. Bras. Ciênc.. Publicado em: 04/05/2017
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4. The Role of Apollon Gene Silencing on Viablity and Radiosensitivity of Cervical Cancer Hela Cells
Cervical cancer is the second common cause of cancer deaths in women worldwide. Radioresistancy of cancer is a principal cause of treatment impairing. Inhibitor of apoptosis proteins (IAPs) widely block apoptosis against apoptotic stimuli, including current chemo- and radiation therapies. Apollon, a membrane of IAP, can support cells against apoptosis and is
Braz. arch. biol. technol.. Publicado em: 06/05/2016
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5. Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer
Abstract Breast cancer is the most common malignancy in women. Radiotherapy is frequently used in patients with breast cancer, but some patients may be more susceptible to ionizing radiation, and increased exposure to radiation sources may be associated to radiation adverse events. This susceptibility may be related to deficiencies in DNA repair mechanisms t
Genet. Mol. Biol.. Publicado em: 24/11/2015
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6. The effect of elemene on lung adenocarcinoma A549 cell radiosensitivity and elucidation of its mechanism
OBJECTIVE:To investigate the effect of elemene on the radiosensitivity of A549 cells and its possible molecular mechanism.METHODS:Apoptosis of A549 cells was detected by flow cytometry and fluorescence microscopy. The effect of double-strand break (DSB) damage repair in A549 cells was evaluated using the neutral comet assay. Protein expression levels were de
Clinics. Publicado em: 2015-08
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7. Alterações morfofisiológicas e bioquímicas em sementes de mamona (Ricinus communis L.) submetidas à Radiação gama Cobalto60 / Alterações morfofisiológicas e bioquímicas em sementes de mamona (Ricinus communis L.) submetidas à Radiação gama Cobalto60 / Morphophysiological and biochemical changes in castor bean seeds (Ricinus communis L.) subjected to gamma Radiation Cobalt-60. / Morphophysiological and biochemical changes in castor bean seeds (Ricinus communis L.) subjected to gamma Radiation Cobalt-60.
O presente estudo teve por objetivo avaliar a radiossensibilidade de sementes de mamona cultivar IAC80 submetida a diferentes doses de radiação gama cobalto60. Primeiramente foi feita a remoção mecânica da carúncula das sementes, foram préembebidas por 24h em água destilada e irradiadas com radiação gama cobalto60 (0, 50, 100, 150 e 200 Gy) e poste
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 01/03/2012
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8. Avaliação do potencial radiossensibilizador de uma tiossemicarbazona derivada de N(4)-Metil-Toluil-2-acetilpiridina e seu complexo de cobre sobre linhagens celulares de tumores cerebrais / Evaluation of the radiosensitizing potential of a thiosemicarbazone derived from N(4)-methyl-tolyl-2- acetylpyridine and its copper complex against brain tumor cell lines
A radioterapia é uma das principais abordagens terapêuticas utilizadas no tratamento do câncer e é indicada, principalmente, em casos onde as lesões são inoperáveis. No entanto, uma de suas limitações advém dos próprios efeitos biológicos da radiação, além de outros fatores tais como a radiorresistência inerente a alguns tipos tumorais, tais
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2010
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9. High expression of the circadian gene mPer2 diminishes the radiosensitivity of NIH 3T3 cells
Period2 is a core circadian gene, which not only maintains the circadian rhythm of cells but also regulates some organic functions. We investigated the effects of mPeriod2 (mPer2) expression on radiosensitivity in normal mouse cells exposed to 60Co-γ-rays. NIH 3T3 cells were treated with 12-O-tetradecanoylphorbol-13-acetate (TPA) to induce endogenous mPer2
Brazilian Journal of Medical and Biological Research. Publicado em: 04/09/2009
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10. Avaliação do dano radioinduzido, capacidade de reparo e morte cecular em células humanas tumorais (T-47D e MCF-7) e não tumorais (MCF-10) de mama / Evaluation of the radioinduced damage, repair capacity and cell death on human tumorigenic (T-47D and MCF-7) and nontumorigenic (MCF-10) cell lines of breast
Breast cancer is one of the most common malignancies that account women, representing about one in three of all female neoplasm. Approximately, 90% of cases are considered sporadic, attributed to somatic events and about 10% have a family history and this only 4 - 5 % is decurrent of hereditary factors. In the clinic, ionizing radiation is a major tool utili
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/07/2008
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11. Influência da radiação gama sobre a micobiota natural de ração avícola e seu efeito sobre a morfologia, fisiologia e genética de cepas de referência de Aspergillus spp. / Influence of gamma irradiation on natural mycoflora of poultry feed and effect on morphology, fisiology and genetic of strains Aspergillus spp.
Irradiação é um processo físico eficazmente utilizado na preservação de alimentos. Este estudo teve como objetivo investigar os efeitos da exposição à radiação gama sobre a micobiota natural de rações avícolas e cepas de Aspergillus spp. Amostras de fubá, farelo de soja e ração foram coletadas diretamente da linha de produção de uma granja
Publicado em: 2008
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12. Uso de substâncias antioxidantes na resposta à radiação dos hidrocolóides carragenanas, agaranas e alginatos utilizados na indústria alimentícia / Use of antioxidants substances to protect the hidrocolloids carrageenan, agaran and alginates used in food industry when expose to radiation
Carrageenan, agaran e alginates are hydrocolloids largely employed in every kind of food products as stabilizing agent and viscosity builder. The human body does not absorb them, so they do not introduce extra calories in the diet. Irradiation is presented as an important alternative method in food preservation because do not induce temperature increase bein
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/02/2006