Rack 1
Mostrando 1-12 de 34 artigos, teses e dissertações.
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1. Estudos funcionais da proteína reguladora humana Ki-1/57 e seus parceiros de interação / Functional studies of the human regulatory protein Ki-1/57 and its interaction partners
The protein Ki-1/57 was discovered through cross reactivity of the monoclonal antibody Ki-1 in cells of Hodgkin lymphoma. Previously studies demonstrated that Ki-1/57 interacts with RACK-1 protein, undergoes phosphorylation by PKCs and methylation by PRMT1, an arginine methyltransferase that modulates several RNA binding proteins. Studies have shown that Ki-
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/07/2011
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2. Thermal and epithermal neutron fluence rates in the irradiation facilities of the TRIGA IPR-R1 nuclear reactor
The TRIGA IPR-R1 nuclear reactor at the Centro de Desenvolvimento da Tecnologia Nuclear CDTN/CNEN, Belo Horizonte, Brazil, has three irradiation facilities: a rotary specimen rack outside the reactor core with 40 irradiation channels which provide large scale isotope irradiation; the central tube placed at the center of the reactor core which permits sample
Brazilian Journal of Physics. Publicado em: 2010-03
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3. Specific induced activity profile at the rotary specimen rack of IPR-R1 TRIGA reactor
The IPR-R1 TRIGA nuclear reactor at Nuclear Technology Development Center, CDTN/CNEN, Belo Horizonte, Brazil, has a rotary specimen rack, RSR, outside the reactor core, and it is composed for forty irradiation channels in a cylindrical geometry. The aim of this work is to evaluate the neutron fluence rate distribution at the RSR and its variation under diffe
Brazilian Journal of Physics. Publicado em: 2009-06
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4. Plasmodium transduction signals aspects. / Aspectos de transdução de sinal em Plasmodium.
A colina quinase, 1ª enzima de uma via que forma 45% da membrana de P. falciparum foi clonada, expressa e purificada, e um anticorpo policlonal desenvolvido. Estudos de transporte da enzima demonstraram que a PfChok é transportada para o citossol por uma via independente do inibidor Brefeldina A. Obteve-se informação da estrutura secundária e uma modela
Publicado em: 2008
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5. Analise das proteinas Ki-1/57 e PRMT1 : identificação, mapeamento e caracterização funcional da interação com outras proteinas / Analysis of the proteins Ki-1/57 and PRMT1: identification, mapping and characterization of the interaction with other proteins
The protein Ki-1/57 that is found both in the cytoplasm and nucleus is associated with serine/threonine protein kinase activity and gets phosphorylated on serine and threonine residues upon cellular activation. We demonstrated that Ki-1/57 interacts with the Chromatin-Helicase-DNA-binding domain protein 3 (CHD3) and with the adaptor/signaling protein RACK1 i
Publicado em: 2006
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6. Functional and structural studies of human regulatory protein Ki-1/57 / Estudos funcionais e estruturais da proteina reguladora humana Ki-1/57
Ki-1/57 é um antígeno humano de 57kDa reconhecido pelo anticorpo Ki-1, o qual também reconhece CD30. Ki-1/57 se encontra no núcleo e no citoplasma sendo fosforilado nos resíduos de serina e de treonina após a ativação das células. Quando Ki-1/57 foi isolado da linhagem L540 de células de linfoma de Hodgkin, ela co-imunoprecipitou com atividade quin
Publicado em: 2005
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7. Stability of vitamins and and in foods enriched with different sources of iron. / Estabilidade das vitaminas A e E em alimentos enriquecidos com diferentes fontes de ferro.
The food enrichment with vitamins and minerals is a very common practice nowadays, allowing to improve the nutritional value of the food and to replace nutrients lost during the processing and or stocking. However, the added nutrients can suffer negative interaction during rack life of the food, as it happens with iron (pro-oxidant) and vitamins A and E (ant
Publicado em: 2004
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8. Estudo do annealing de traços de fissão em apatitas, tanto em seções basais como em seções sem orientação preferencial, a partir do comprimento e da densidadede de traços de fissão
We studied the annealing of fission track in apatite aiming two goals: to be able to produce na experimental data set that is more complete than those found in the literature and to contribute to a better understanding of this process. We measured superficial density of fission tracks and estricted length measurements to the tracks totally confined inside th
Publicado em: 1998
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9. An autoregulatory region in protein kinase C: the pseudoanchoring site.
We have previously identified receptors for activated C kinase (RACKs) as components of protein kinase C (PKC) signaling. RACK1, a recently cloned 36-kDa RACK, has short sequences of homology to PKC. A possible explanation for the homologous sequences between the ligand (PKC) and its intracellular receptor (RACK1) may be that, similar to the pseudosubstrate
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10. RACK1 binds to inositol 1,4,5-trisphosphate receptors and mediates Ca2+ release
RACK1 is not a G protein but closely resembles the heterotrimeric Gβ-subunit. RACK1 serves as a scaffold, linking protein kinase C to its substrates. We demonstrate that RACK1 physiologically binds inositol 1,4,5-trisphosphate receptors and regulates Ca2+ release by enhancing inositol 1,4,5-trisphosphate receptor binding affinity for inositol 1,4,5-trisphos
National Academy of Sciences.
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11. Phosphorylation of RACK1 on Tyrosine 52 by c-Abl Is Required for Insulin-like Growth Factor I-mediated Regulation of Focal Adhesion Kinase*
Focal Adhesion Kinase (FAK) activity is controlled by growth factors and adhesion signals in tumor cells. The scaffolding protein RACK1 (receptor for activated C kinases) integrates insulin-like growth factor I (IGF-I) and integrin signaling, but whether RACK1 is required for FAK function is unknown. Here we show that association of FAK with RACK1 is require
American Society for Biochemistry and Molecular Biology.
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12. RACK1 Regulates Integrin-mediated Adhesion, Protrusion, and Chemotactic Cell Migration via Its Src-binding SiteV⃞
Mammalian cDNA expression cloning was used to identify novel regulators of integrin-mediated cell-substratum adhesions. Using a focal adhesion morphology screen, we identified a cDNA with homology to a receptor for activated protein kinase C (RACK1) that induced a loss of central focal adhesions and stress fibers in CHO-K1 cells. The identified cDNA was a C-
The American Society for Cell Biology.