Quantitative Modelling
Mostrando 1-12 de 30 artigos, teses e dissertações.
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1. Molecular Modelling Study of Heteroarylamide/Sulfonamide Compounds with Antitrypanosomal Activity
According to the World Health Organization (WHO), Chagas disease (CD), whose etiological agent is the Trypanosoma cruzi (T. cruzi) parasite, affects about eight million people, mainly in Latin America. The cruzain enzyme is highlighted among the main biological targets, since it is the most abundant of the cysteine protease class from T. cruzi and is involve
J. Braz. Chem. Soc.. Publicado em: 2021-01
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2. Puls method for events simulation in a lot scale bioretention device
RESUMO Biorretenção é uma técnica aplicada para tratar e reduzir o escoamento superficial gerado em áreas urbanas. Embora essas instalações apresentem processos complexos, um modelo simples com poucos parâmetros pode ser útil para seu projeto. Este artigo relata uma aplicação do método Puls como uma ferramenta quantitativa de simulação de biorr
RBRH. Publicado em: 22/08/2019
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3. A short remark on the modelling of a three-story shear-building structure
Abstract In this note, some remarks on the modelling of a multi-degree-of-freedom system, a three-story shear-building structure, is presented. The modelling of a mechanical system is one of the most important aspects in engineering and physics, since is crucial for the understanding of the system. Besides, the model, if properly made, can be also useful to
Rev. Bras. Ensino Fís.. Publicado em: 21/09/2018
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4. NIR Monitoring and Modelling of Soybean Oil Methanolysis with Multivariate Curve Resolution-Alternating Least Squares with Correlation Constraint
Near infrared spectroscopy in-line monitoring and modelling of soybean oil methanolysis has been done using multivariate curve resolution alternating least squares (MCR-ALS) with correlation constraint. This constraint allows for quantitation of the methyl ester formed with little calibration effort and the MCR model provides additionally a general descripti
J. Braz. Chem. Soc.. Publicado em: 2017-05
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5. Comparison of optical microscopy and quantitative polymerase chain reaction for estimating parasitaemia in patients with kala-azar and modelling infectiousness to the vector Lutzomyia longipalpis
Currently, the only method for identifying infective hosts with Leishmania infantum to the vector Lutzomyia longipalpis is xenodiagnosis. More recently, quantitative polymerase chain reaction (qPCR) has been used to model human reservoir competence by assuming that detection of parasite DNA indicates the presence of viable parasites for infecting vectors. Si
Mem. Inst. Oswaldo Cruz. Publicado em: 18/07/2016
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6. Computational drug design strategies applied to the modelling of human immunodeficiency virus-1 reverse transcriptase inhibitors
Reverse transcriptase (RT) is a multifunctional enzyme in the human immunodeficiency virus (HIV)-1 life cycle and represents a primary target for drug discovery efforts against HIV-1 infection. Two classes of RT inhibitors, the nucleoside RT inhibitors (NRTIs) and the nonnucleoside transcriptase inhibitors are prominently used in the highly active antiretrov
Mem. Inst. Oswaldo Cruz. Publicado em: 2015-11
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7. Intrusive versus domiciliated triatomines and the challenge of adapting vector control practices against Chagas disease
Chagas disease prevention remains mostly based on triatomine vector control to reduce or eliminate house infestation with these bugs. The level of adaptation of triatomines to human housing is a key part of vector competence and needs to be precisely evaluated to allow for the design of effective vector control strategies. In this review, we examine how the
Mem. Inst. Oswaldo Cruz. Publicado em: 14/03/2015
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8. Numerical simulation of anisotropic polymeric foams
This paper shows in detail the modelling of anisotropic polymeric foam under compression and tension loadings, including discussions on isotropic material models and the entire procedure to calibrate the parameters involved. First, specimens of poly(vinyl chloride) (PVC) foam were investigated through experimental analyses in order to understand the mechanic
Lat. Am. j. solids struct.. Publicado em: 2012-04
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9. Modelagem molecular de uma série de compostos inibidores da enzima integrase do vírus HIV-1 / Molecular modelling for a series of integrase HIV-I inhibitors
An essential step in the HIV life cycle is integration of the viral DNA into the host chromosome. This step is catalyzed by a 32-kDa viral enzyme HIV integrase (IN). HIV-1 IN is an important and validated target, and the drugs that selectively inhibit this enzyme, when used in combination with reverse transcriptase (RT) and protease (PR) inhibitors, are beli
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 20/07/2011
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10. Proposta Metodológica Para Avaliação Quantitativa da Fase Rápida da Curva Força-Tempo na Preensão Manual de Pacientes com Doença Renal Crônica / Methodological proposal for quantitative assessment of the fast phase of the handgrip force-time curve with chronic kidney disease patients.
A Doença Renal Crônica (DRC) é caracterizada pela perda da capacidade de filtragem dos rins. O paciente com DRC tem diminuição dos níveis de força muscular e de condicionamento físico, os quais estão diretamente ligados à qualidade de vida e à realização das atividades da vida diária. A atividade física, especificamente o treinamento de força
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 25/03/2011
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11. Aplicação de um modelo cognitivo para análise de tomada de decisão em ambiente de desenvolvimento orçamentário
The models usually used by the companies to monitor and to foresee the decision making process, searching for the ideal level of success in decisions, in many cases they are not appropriate. This happens because many of these decisions involve aspects that could not be foreseen in the rational models of the decision making process, like the intuition of the
Publicado em: 2010
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12. Decisão de mix de produtos sob a ótica do custeio baseado em atividades e tempo. / Product-mix decision from the perspective of time-driven activity-based costing.
Esta pesquisa versa sobre o tema decisão de mix de produtos que, em uma visão de Gestão de Produção e Operações, pode ser entendido como a definição da quantidade ideal a ser produzida de cada tipo de produto em um determinado período, considerando que estes competem por um número limitado de recursos, de forma a maximizar o resultado econômico (
Publicado em: 2010