Proteins
Mostrando 1-12 de 59414 artigos, teses e dissertações.
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1. Effects of antidiabetics and exercise therapy on suppressors of cytokine signaling-1, suppressors of cytokine signaling-3, and insulin receptor substrate-1 molecules in diabetes and obesity
SUMMARY OBJECTIVE: Pathological destruction of insulin signaling molecules such as insulin receptor substrate, especially due to the increase in suppressors of cytokine signaling molecules, has been demonstrated in experimental diabetes. The contribution of suppressors of cytokine signaling proteins to the development of insulin resistance and the effects o
Revista da Associação Médica Brasileira. Publicado em: 2023
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2. Increased expression of matrix metalloproteinases 2 and 9 as poor prognosis factor for Hodgkin’s lymphoma patients
Abstract Objective: The aim of our study was to evaluate the expression of MMP-2 and MMP-9 as a prognostic factor in patients diagnosed with Hodgkin Lymphoma (HL). Methods: In the present study, 45 paraffin biopsies from patients up to 19 years old diagnosed with HL were used in two referral hospitals in the state of Pernambuco, Brazil. Risk groups were cl
Jornal de Pediatria. Publicado em: 2023
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3. Molecular Docking in silico Analysis of Brazilian Essential Oils Against Host Targets and SARS-CoV-2 Proteins
The inhibitory activity of thirty-one sesquiterpenes identified from Brazilian essential oils (Copaifera langsdorffii Desf., Croton cajucara Benth. and Siparuna guianensis Aublet.) were analyzed by in silico molecular docking. The compounds were characterized by gas chromatography-mass spectrometry (GC-MS) and gas chromatography with flame-ionization detecti
Journal of the Brazilian Chemical Society. Publicado em: 2022
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4. Changes in gap junction proteins Connexin30.2 and Connexin40 expression in the sinoatrial node of rats with dexmedetomidine-induced sinus bradycardia
Abstract Background Dexmedetomidine (Dex) is widely used, and its most common side effect is bradycardia. The complete mechanism through which Dex induces bradycardia has not been elucidated. This research investigates the expression of gap junction proteins Connexin30.2 (Cx30.2) and Connexin40 (Cx40) within the sinoatrial node of rats with Dex-induced sinu
Brazilian Journal of Anesthesiology. Publicado em: 2022
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5. Cow’s milk allergy immunoglobulin E-mediated: intake of proteins and amino acids
SUMMARY OBJECTIVE: Children with cow’s milk allergy may be at nutritional risk due to the lower intake of nutrients, such as protein, calcium, and vitamin A, which are present in cow’s milk. The objective was to evaluate children’s diets with Children with cow’s milk allergy compared with healthy controls as well as to compare the intake of proteins
Revista da Associação Médica Brasileira. Publicado em: 2022
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6. Update on the pathogenesis of vitiligo
Abstract Vitiligo is a complex disease whose pathogenesis results from the interaction of genetic components, metabolic factors linked to cellular oxidative stress, melanocyte adhesion to the epithelium, and immunity (innate and adaptive), which culminate in aggression against melanocytes. In vitiligo, melanocytes are more sensitive to oxidative damage, lead
Anais Brasileiros de Dermatologia. Publicado em: 2022
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7. Self-reported symptoms and seroprevalence against SARS-CoV-2 in the population of Mato Grosso: a household-based survey in 2020
SUMMARY OBJECTIVE: This study aimed to analyze the association between self-reported symptoms and seroprevalence against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the population of Mato Grosso. METHODS: A household-based survey was conducted on 4,206 adults from 10 municipalities of Mato Grosso, in the Brazilian Midwest, who were sele
Revista da Associação Médica Brasileira. Publicado em: 2022
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8. Transmission electron microscopy of pili annulati
Abstract Background: Little is known about the ultrastructure of pili annulati. Objectives: To examine with transmission electron microscopy affected hairs of a family, whose diagnosis had been confirmed in five individuals with scanning electron microscopy, which showed surface undulations with ‘‘curtain-like’’ folding of the hair cuticula and to
Anais Brasileiros de Dermatologia. Publicado em: 2022
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9. Two cases of subacute thyroiditis after different types of SARS-CoV-2 vaccination
SUMMARY Although the development of subacute thyroiditis (SAT) following viral infections is well-documented, the actual mechanism has not been clearly elucidated. The occurrence of SAT after vaccination has been reported in several case series and possible mechanisms such as molecular mimicry due to the exposure to viral proteins and/or abnormal reactogenic
Archives of Endocrinology and Metabolism. Publicado em: 2022
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10. Prognostic importance of expression of mini-chromosome maintenance proteins (MCMs) in patients with nasopharyngeal cancer treated with curative radiotherapy
Abstract Objective: The prognostic importance of minichromosome maintenance complex expression in nasopharyngeal cancer is still unknown. We aimed to find whether minichromosome maintenance complex 2–7 expression may potentially be used to predict the prognosis of nasopharyngeal cancer patients treated with definitive radiotherapy. Methods: Between April
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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11. Evaluación del consumo de macronutrientes y micronutrientes por individuos prediabéticos
Abstract: Background The diet is an important strategy for glycemic control as well as reducing/eliminating the risk of developing diabetes. Objective This article evaluated the consumption of macronutrients and micronutrients of pre-diabetic individuals from Santa Cruz do Sul, in the state of Rio Grande do Sul (RS), Brazil. Method The nutrients intake wa
Cadernos Saúde Coletiva. Publicado em: 2022
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12. EFFECT OF MERCURY EXPOSURE ON U1-70 KDA PROTEIN EXPRESSION IN EMBRYOS OF BLACK BEAN (Phaseolus vulgaris L.)
Exposure to heavy metals has been documented to induce changes in the expression of plant proteins. Phaseolus vulgaris L., represents a great source of nutrition for millions of people, and is the second most important legume crop. The present study aimed to investigate the effects of Hg stress on germination rate and identify the gene expression profiling o
Química Nova. Publicado em: 2022