Proteinase Inhibitors
Mostrando 1-12 de 263 artigos, teses e dissertações.
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1. Subproteome of Lachesis muta rhombeata venom and preliminary studies on LmrSP-4, a novel snake venom serine proteinase
Abstract Background: Lachesis muta rhombeata is one of the venomous snakes of medical importance in Brazil whose envenoming is characterized by local and systemic effects which may produce even shock and death. Its venom is mainly comprised of serine and metalloproteinases, phospholipases A2 and bradykinin-potentiating peptides. Based on a previously report
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 15/04/2019
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2. Trypsin inhibitor from tamarindus indica L. seeds reduces weight gain and food consumption and increases plasmatic cholecystokinin levels
OBJECTIVES: Seeds are excellent sources of proteinase inhibitors, some of which may have satietogenic and slimming actions. We evaluated the effect of a trypsin inhibitor from Tamarindus indica L. seeds on weight gain, food consumption and cholecystokinin levels in Wistar rats. METHODS: A trypsin inhibitor from Tamarindus was isolated using ammonium sulfate
Clinics. Publicado em: 2015-02
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3. Kazal-type serine proteinase inhibitors in the midgut of Phlebotomus papatasi
Sandflies (Diptera: Psychodidae) are important disease vectors of parasites of the genus Leishmania, as well as bacteria and viruses. Following studies of the midgut transcriptome of Phlebotomus papatasi, the principal vector of Leishmania major, two non-classical Kazal-type serine proteinase inhibitors were identified (PpKzl1 and PpKzl2). Analyses of expres
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-09
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4. Isolated biomolecules of pharmacological interest in hemostasis from Cerastes cerastes venom
Biomolecules from Cerastes cerastes venom have been purified and characterized. Two phospholipases isolated from Cerastes cerastes venom share 51% of homology. CC2-PLA2 exhibits antiplatelet activity that blocks coagulation. CCSV-MPase, a non-hemorrhagic Zn2+-metalloproteinase, significantly reduced the plasmatic fibrinogen level and hydrolyzes only its Bβ
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 01/05/2013
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5. Indução e redução de defesas em plantas de tomate por ácaros fitófagos: efeitos de ataques sequenciais e simultâneos / Induction and reduction of tomato plant defenses by spider mites: effects of sequential and simultaneous attacks
Neste estudo foi investigado o efeito das defesas induzidas diretas de plantas de tomate sobre parâmetros biológicos do ácaro vermelho Tetranychus evansi Baker &Pritchard (Acari: Tetranychidae) e do ácaro rajado Tetranychus urticae Koch (Acari: Tetranychidae), pelo fato desses ácaros serem pragas na cultura do tomateiro. No primeiro capítulo foram dete
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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6. A pipeline to study structural interactions among Spodoptera frugiperda serine proteinases and plant proteinase inhibitors.
We propose here a computational biology pipeline to identify and analyze possible structural determinants that could explain some level of insensitivity by S. frugiperda serine proteinases (SPs) against plant PIs observed in a real time PCR experiment.
CONGRESSO BRASILEIRO DE GENÉTICA. Publicado em: 2011
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7. Caracterização estrutural da interação de serino proteinases de Spodoptera frugiperda (Lepidoptera: Noctuidae) e inibidores de proteinases de plantas / Structural characterisation of Spodoptera frugiperda (Lepidoptera: Noctuidae) serine proteinase interactions with plant proteinase inhibitors.
As plantas desenvolveram diferentes mecanismos para reduzir o ataque de insetos, incluindo compostos protéicos de defesa, como os inibidores de proteinases (IPs). Os insetos, ao longo da evolução, desenvolveram estratégias para superar as barreiras defensivas das plantas, permitindo a sua alimentação e desenvolvimento, como a super expressão de genes
Publicado em: 2011
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8. Estudo retrospectivo do tratamento ambulatorial da úlcera indolente em cães da raça Boxer / Retrospective study of clinical management of indolent ulcers in Boxer dogs
Úlceras indolentes são úlceras corneais superficiais, espontâneas, que apresentam curso prolongado e que tendem a recidivar. Comumente observadas em cães de meia idade, da raça Boxer, provoca dor de início agudo e necessita de tratamento específico, já que este, quando não realizado de forma correta, pode prolongar o curso da lesão por semanas a m
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 24/11/2010
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9. Erratum to "Action of plant proteinase inhibitors on enzymes of physiopathological importance" [An Acad Bras Cienc 81(2009): 615-621]
Anais da Academia Brasileira de Ciências. Publicado em: 2010-06
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10. Influência da qualidade de diferentes tipos de arroz e inibidores de proteinases no rendimento e na virulência de conídios do fungo entomopatogênico Metarhizium anisopliae (Mestch.) Sorokin (Ascomycota: Hypocreales) / Influence of quality of different types of rice and proteinase inhibitors on yield and virulence of conidia of the entomopathogenic fungus Metarhizium anisopliae (Mestch.) Sorokin (Ascomycota: Hypocreales)
In order to optimize the production process of Metarhizium anisopliae, the present study aimed to determine the effects of soybean proteinase inhibitors on growth, sporulation and virulence of the fungus and to compare yield, viability and virulence of M. anisopliae conidia produced in different types of rice and additives. The addition of 5 g.L-1 of semi-pu
Publicado em: 2010
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11. Endossimbiose de Tetranychus evansi Baker e Pritchard (Acari: Tetranychidae) e a resposta de defesa induzida em tomateiro / Endosymbioses of Tetranychus evansi Baker and Pritchard (Acari: Tetranychidae) and tomato induced defence response
Interactions between arthropods and microorganisms have been receiving more attention due to the impact that these symbiotic associations causes on their macrosymbionts. Reproduction is the main biological parameters affected with cytoplasmic incompatibility and thelytokous parthenogenesis; however, endosymbionts can help arthropods to exploit host plants. I
Publicado em: 2010
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12. Perfil metabólico de duas variedades transgênicas de cana-de-açúcar modificadas com os genes inibidores de proteinase Bowman-Birk e Kunitz / Metabolic profile of two transgenic varieties of sugarcane modified with proteinase inhibitors Bowman-Bir and Kunitz
A demanda comercial de produtos derivados da cana-de-açúcar é a grande motivadora do aprimoramento genético com a finalidade de proporcionar a planta aumento no acúmulo de sucrose e/ou de resistência a ataques de herbívoros. Assim sendo, este trabalho abrange o estudo metabolomico de duas variedades transgênicas da cana-de-açúcar (Bowman-Birk-SBBI
Publicado em: 2010