Progesterone Receptor
Mostrando 1-12 de 392 artigos, teses e dissertações.
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1. Immunohistochemical and clinicopathologic features of estrogen receptor-negative, progesterone receptor-positive, HER-2 negative breast carcinomas
SUMMARY OBJECTIVE: Currently, there is an ongoing debate whether progesterone receptor positive and estrogen receptor negative breast carcinomas represent a true distinct subtype of tumor or a mere immunohistochemical artifact. In this study, we conducted an immunohistochemistry panel with the antibodies TFF1, EGFR, and CK5 to reclassify this phenotype in a
Rev. Assoc. Med. Bras.. Publicado em: 2021-02
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2. Immunohistochemical assessment of symptomatic postmenopausal endometrial polyps in tamoxifen users and nonusers: a case control study
ABSTRACT BACKGROUND: Endometrial polyps are common in postmenopausal women, and the effect of tamoxifen use (a risk factor for endometrial polyps) on their pathogenesis is unclear. OBJECTIVES: To evaluate the expression of hormone receptors and markers for proliferation/apoptosis (Ki-67 and Bcl-2) in endometrial polyps in postmenopausal users and nonuser
Sao Paulo Med. J.. Publicado em: 2020-02
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3. Immunohistochemical localization of progesterone receptors alpha (PRA) in ovary of the pseudopregnant rabbit
Abstract Progesterone plays an important role in the reproductive function and follicular development in mammals. The aim of the present study was to examine the localization of progesterone receptor alpha (PRA) in ovary of pseudopregnant rabbit by immunohistochemical methods. Samples were collected from 14 h. to 18 days of pseudopregnancy. At the first stag
Anim. Reprod.. Publicado em: 25/11/2019
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4. Comparative analysis of the histopathological and epidemiological profile of ductal and lobular breast carcinomas diagnosed at the Hospital de Clínicas da Universidade Federal do Paraná during the period 2008-2013
RESUMO Introdução: O câncer da mama éa segunda causa de morte por câncer entre as mulheres em todo o mundo, e estuáis epidemiológicos podem auxiliar no entendimento dos seus mecanismos. Objetivos: Realizar um levantamento do número de casos dos carcinomas da mama diagnosticados em um período de seis anos. Método: Foi comparado com a literatura o
J. Bras. Patol. Med. Lab.. Publicado em: 09/05/2019
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5. Establishment of a rat model for uterine leiomyomas based on Western and traditional Chinese medicine theories
Uterine leiomyomas (ULs) are benign monoclonal tumors that arise from the underlying myometrial tissue in the uterus. Effective therapies are still lacking because of poor understanding of the pathophysiology and epidemiology. Hence, it is urgent to establish efficient animal models to screen novel anti-UL therapies. In this study, for the first time, tradit
Braz J Med Biol Res. Publicado em: 02/07/2018
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6. Expression of estrogen and progesterone receptors in astrocytomas: a literature review
Gliomas are the most common type of primary central nervous system neoplasm. Astrocytomas are the most prevalent type of glioma and these tumors may be influenced by sex steroid hormones. A literature review for the presence of estrogen and progesterone receptors in astrocytomas was conducted in the PubMed database using the following MeSH terms: “estrogen
Clinics. Publicado em: 2016-08
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7. Protein Expression and Codon 72 Polymorphism of TP53 Gene in Triple Negative Breast Cancer
A subgroup of tumor that has received attention is triple-negative breast cancer (TNBC), which presents phenotype of negative estrogen receptor, negative progesterone receptor and has no overexpression of HER2. TP53 acts as a tumor suppressor limiting the proliferation of damaged cells. A polymorphic site (rs1042522) of TP53 encodes either an arginine or a p
Braz. arch. biol. technol.. Publicado em: 2014-12
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8. Culture of bovine ovarian follicle wall sections maintained the highly estrogenic profile under basal and chemically defined conditions
Follicle cultures reproduce in vitro the functional features observed in vivo. In a search for an ideal model, we cultured bovine antral follicle wall sections (FWS) in a serum-free defined medium (DM) known to induce 17β-estradiol (E2) production, and in a nondefined medium (NDM) containing serum. Follicles were sectioned and cultured in NDM or DM for 24 o
Braz J Med Biol Res. Publicado em: 16/08/2013
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9. Basal cytokeratin as a potential marker of low risk of invasion in ductal carcinoma in situ
OBJECTIVES: Biological markers that predict the development of invasive breast cancer are needed to improve personalized therapy for patients diagnosed with ductal carcinoma in situ. We investigated the role of basal cytokeratin 5/6 in the risk of invasion in breast ductal carcinoma in situ. METHODS: We constructed tissue microarrays using 236 ductal carc
Clinics. Publicado em: 2013-05
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10. Expressão do HER-2 em pacientes brasileiras com carcinoma da mama receptor de estrógeno e progesterona negativo / HER-2 expression in Brazilian patients with estrogen and progesterone receptor-negative breast carcinoma
Introdução: O câncer da mama é a segunda neoplasia mais frequente no mundo. Sem considerar os tumores de pele não melanoma, é a neoplasia mais incidente no sexo feminino. No Brasil, a estimativa do câncer da mama para o ano de 2012 é de 52.608 novos casos. Os cânceres da mama que não expressam receptores de estrógeno (RE) e progesterona (RP) apres
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012
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11. Estrogen and progesterone receptors in endometrial polyps of women exposed and not exposed to tamoxifen and in atrophic endometrium / Receptores de estrógeno e progesterona em pólipos endometriais de usuárias e não usuárias de tamoxifeno e no endométrio atrófico
Introduction: Tamoxifen has been used for the treatment of strogen receptor-positive breast cancer. The effect of tamoxifen in breast cancer is the it inhibition cancer cell growth by competitive antagonism with strogen for strogen receptor (ER). The mechanism of action of tamoxifen in this receptor varies among different tissues, with antagonist effect (e.g
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/02/2012
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12. Estrous cycle and stress: influence of progesterone on the female brain
The female brain operates in a constantly changing chemical milieu caused by cyclical changes in gonadal hormones during the estrous cycle (menstrual cycle in women). Such hormones are highly lipophilic and pass readily from the plasma to the brain where they can influence neuronal function. It is becoming clear that the rapid reduction in peripheral circula
Brazilian Journal of Medical and Biological Research. Publicado em: 2012-04