Primaquine Diphosphate
Mostrando 1-3 de 3 artigos, teses e dissertações.
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1. A newly validated high-performance liquid chromatography method with diode array ultraviolet detection for analysis of the antimalarial drug primaquine in the blood plasma
Abstract INTRODUCTION: Primaquine (PQ) diphosphate is an 8-aminoquinoline antimalarial drug with unique therapeutic properties. It is the only drug that prevents relapses of Plasmodium vivax or Plasmodium ovale infections. In this study, a fast, sensitive, cost-effective, and robust method for the extraction and high-performance liquid chromatography with
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-08
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2. Optimization of controlled release primaquine diphosphate tablets / Otimização da liberação de difosfato de primaquina em comprimidos de liberação controlada
The objective of the present work was to produce primaquine diphosphate controlled release tablets based on hydrophilic polymers and use the mixture statistical experimental design (DOE) to optimize drug release. In selecting the components of the formulations, differential scanning calorimetry (DSC) were carried out to verify the compatibility between drug/
Publicado em: 2009
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3. Primaquine Diphosphate: Inhibition of Newcastle Disease Virus Replication
The response of Newcastle disease virus replication to primaquine, an antimalarial drug, was examined in chicken embryo cells (CEC). Virus-induced hemadsorption was completely inhibited by 250 μg of primaquine per ml. At lower concentrations, hemadsorption inhibition was dose dependent. Primaquine retarded virus-induced redistribution of receptor sites on t