Peripheral Nervous System Disease
Mostrando 1-12 de 134 artigos, teses e dissertações.
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1. Armadillos and leprosy: from infection to biological model
ABSTRACT Mycobacterium leprae is the primary causative agent of Hansen’s disease or leprosy. Besides human beings, natural infection has been described in animals such as mangabey monkeys and armadillos. Leprosy is considered a global health problem and its complete pathogenesis is still unknown. As M. leprae does not grow in artificial media, armadillos h
Rev. Inst. Med. trop. S. Paulo. Publicado em: 12/09/2019
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2. Granulomatosis with polyangiitis in Northeastern Brazil: study of 25 cases and review of the literature
Abstract Background: Little has been published about the epidemiology of Granulomatosis with polyangiitis (GPA) in South America, especially in the intertropical zone, and no epidemiological data from Brazil are available. The purpose of the present study was to draw a clinical and demographic profile of GPA patients living in Northeastern Brazil based on l
Adv. rheumatol.. Publicado em: 29/07/2019
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3. Small Fiber Neuropathy in Fabry Disease: a Review of Pathophysiology and Treatment
Abstract Fabry disease is an inherited metabolic disorder characterized by progressive lysosomal accumulation of glycolipids in a variety of cell types, including neural cells. Small, unmyelinated nerve fibers are particularly affected and small fiber peripheral neuropathy often clinically manifests at a young age. Neuropathic pain and pain attacks are often
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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4. Spatial approach of leprosy in the State of São Paulo, 2009-2012
Abstract: Background: Leprosy is a chronic, infectious disease that affects the skin and the peripheral nervous system and can lead to permanent disability and/or deformity. Objectives: To identify the distribution and to quantify the spatial dependence of the detection rates of new cases of Hansen’s disease in the State of São Paulo, correlating with s
An. Bras. Dermatol.. Publicado em: 2019-02
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5. Opioids in the immune system: from experimental studies to clinical practice
RESUMO INTRODUÇÃO: Os opioides interagem com ambos os sistemas imunes, inato e adaptativo, através de efeitos diretos sobre os receptores dos opioides localizados nas células imunes. As pesquisas neste assunto têm fornecido evidência da influência dos opioides sobre a resposta imune associada ao estresse cirúrgico. Os efeitos imunológicos dos opioi
Rev. Assoc. Med. Bras.. Publicado em: 2019-02
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6. Multiple uses of fibrin sealant for nervous system treatment following injury and disease
Abstract Lesions to the nervous system often produce hemorrhage and tissue loss that are difficult, if not impossible, to repair. Therefore, scar formation, inflammation and cavitation take place, expanding the lesion epicenter. This significantly worsens the patient conditions and impairment, increasing neuronal loss and glial reaction, which in turn furthe
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 27/04/2017
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7. qPCR detection of Mycobacterium leprae in biopsies and slit skin smear of different leprosy clinical forms
Abstract Leprosy, whose etiological agent is Mycobacterium leprae, is a chronic infectious disease that mainly affects the skin and peripheral nervous system. The diagnosis of leprosy is based on clinical evaluation, whereas histopathological analysis and bacilloscopy are complementary diagnostic tools. Quantitative PCR (qPCR), a current useful tool for diag
Braz J Infect Dis. Publicado em: 2017-02
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8. Pili canaliculi as manifestation of giant axonal neuropathy
Abstract Giant axonal neuropathy is a rare autosomal recessive neurodegenerative disease. The condition is characterized by neurons with abnormally large axons due to intracellular filament accumulation. The swollen axons affect both the peripheral and central nervous system. A 6-year old female patient had been referred to a geneticist reporting problems wi
An. Bras. Dermatol.. Publicado em: 2016-10
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9. Familial Dysautonomia: Mechanisms and Models
Abstract Hereditary Sensory and Autonomic Neuropathies (HSANs) compose a heterogeneous group of genetic disorders characterized by sensory and autonomic dysfunctions. Familial Dysautonomia (FD), also known as HSAN III, is an autosomal recessive disorder that affects 1/3,600 live births in the Ashkenazi Jewish population. The major features of the disease are
Genet. Mol. Biol.. Publicado em: 04/08/2016
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10. Syndrome in question
Abstract Ross syndrome is a rare disease characterized by peripheral nervous system dysautonomia with selective degeneration of cholinergic fibers. It is composed by the triad of unilateral or bilateral segmental anhidrosis, deep hyporeflexia and Holmes-Adie's tonic pupil. The presence of compensatory sweating is frequent, usually the symptom that most affli
An. Bras. Dermatol.. Publicado em: 2016-02
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11. Análise molecular de polimorfismos nos genes HLA-ClASSE II DRB1* e IL7R? possivelmente associados com a susceptibilidade à esclerose múltipla em uma amostra da população do Rio de Janeiro
Multiple sclerosis (MS) is an inflammatory and degenerative disease of the central nervous system (CNS) that affects mainly young adults. MS seems to be a polygenic and multifactorial disease, and genetic susceptibility has been associated mainly with the major histocompatibility complex (MHC), which in humans is the human leukocyte antigen (HLA). Among non-
Arq. Neuro-Psiquiatr.. Publicado em: 2014-06
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12. Alteraciones morfológicas en las mitocondrias en la piel de enfermos con esclerosis lateral amiotrófica esporádica
OBJECTIVES: Mitochondrial dysfunction has been reported in the central nervous system, hepatocytes and peripheral blood lymphocytes from patients with sporadic amyotrophic lateral sclerosis (SALS). However, the status of skin mitochondria has not been reported, in spite of the fact that SALS patients present skin abnormalities. The objective of the present s
Arquivos de Neuro-Psiquiatria. Publicado em: 2012-01