Penicillamine Urine
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Utilization of a novel Ag(III)-luminol chemiluminescence system for determination of d-penicillamine in human urine samples
Um novo sistema de quimioluminescência (CL), sensível, (reação [Ag(HIO6)2]5--luminol), acoplado com injeção em fluxo, é introduzido para determinação de d-penicilamina. O sistema é baseado no efeito do aumento da reação de quimioluminescência por penicilamina em meio alcalino. Sob condições ótimas, a intensidade de CL é proporcional às conc
Journal of the Brazilian Chemical Society. Publicado em: 2011-08
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2. Cupriuresis in parents of patients with Wilson disease before and after oral intake of d-penicillamine / Cuprúria em pais de pacientes com doença de Wilson antes e depois da administração oral de d-penicilamina
Wilson disease is a biliary copper excretion disturbance, of recessive autossomic heritage, due to ATP7B gene mutations. The copper not bound to apoceruloplasmin circulates in the organism bound to amino acids and accumulates mainly in the liver and brain being excreted by the kidneys. Urinary copper higher than 100ug/24h can be useful in the diagnosis, but
Publicado em: 2007
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3. Different behaviour of inorganic and organic mercury in renal excretion with reference to effects of D-penicillamine.
Inorganic and organic mercury was measured in the red cells, plasma, and urine of five laboratory workers to examine the effect of D-penicillamine. The workers had had no particular exposure to mercurials. Before and during administration of D-penicillamine, inorganic mercury levels in plasma were significantly correlated with those in urine or 24-hour urina
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4. Effect of Organic Mercurials and Sulfhydryl Compounds on the Urease Activity of Proteus: Inhibition by Urine and Ascorbic Acid
Meralluride, mercaptomerin, ethacrynic acid, and penicillamine inhibited urease activity of Proteus mirabilis. The activity of the organic mercurials and ethacrynic acid was markedly inhibited by human and dog urine. Antiurease activity could not be detected in the urine of a human and a dog given meralluride by injection. Urine from patients receiving penic
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5. Treatment of Lead Poisoning: A Comparison between the Effects of Sodium Calciumedetate and Penicillamine Administered Orally and Intravenously1
In 16 workers with lead poisoning of varying degrees, a comparison was made between the therapeutic efficacy of sodium calciumedetate (Ca-EDTA) and penicillamine (PCA), administered intravenously and orally. The question of comparable dosages of ligands, forming metal complexes in different ways, is discussed. With the dosages given, intravenous Ca-EDTA prom
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6. Resumption of treatment with penicillamine after proteinuria.
Penicillamine has been successfully reintroduced and continued for a minimum of 13 months in 5 patients who developed proteinuria during the first course of the drug. The daily maintenance dose during the second course was 150--250 mg taken midway between 2 meals. Proteinuria did not recur; no significant excretion of fibrin degradation products occurred; co
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7. Fate of the gold and the thiomalate part after intramuscular administration of aurothiomalate to mice.
Double isotope-labelled aurothiomalate (195Au-14C-thiomalate) has been administered to mice, and the excretory fate and tissue distribution have been studied. The results show that the gold and the thiomalate separate in vivo resulting in protein-bound gold and release of free thiomalate. About half of this thiol is excreted in the urine during the first day
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8. Microalbuminuria in patients with rheumatoid arthritis.
OBJECTIVES--To assess (a) the prevalence of microalbuminuria in patients with rheumatoid arthritis, (b) the association between urinary albumin excretion and disease activity as estimated by the erythrocyte sedimentation rate and C reactive protein (CRP), and (c) the association between urinary albumin excretion and treatment with antirheumatic drugs. METHOD