Pancreatic Alteration
Mostrando 1-12 de 37 artigos, teses e dissertações.
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1. Pancreatic endosonographic findings and clinical correlation in Crohn's disease
OBJECTIVES: We aimed to evaluate the incidence of pancreatic alterations in Crohn's disease using endoscopic ultrasound (EUS) and to correlate the number of alterations with current clinical data. METHODS: Patients diagnosed with Crohn's disease (n=51) were examined using EUS, and 11 variables were analyzed. A control group consisted of patients with no hi
Clinics. Publicado em: 30/05/2019
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2. Heterotaxy syndrome with agenesis of dorsal pancreas and diabetes mellitus: case report and review of the literature
SUMMARY Heterotaxy syndrome (HS) is a rare congenital condition with multifactorial heritance, characterized by an abnormal arrangement of thoraco-abdominal organs and vessels. Patients present with multiple cardiac, gastrointestinal, hepatosplenic, pancreatic, renal, neurological and skeletal disorders without any pathognomonic alteration. Despite the descr
Arch. Endocrinol. Metab.. Publicado em: 30/05/2019
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3. Searching for mutations in the HNF1B gene in a Brazilian cohort with renal cysts and hyperglycemia
ABSTRACT Objective To verify the presence of variants in HNF1B in a sample of the Brazilian population selected according to the presence of renal cysts associated with hyperglycemia. Subjects and methods We evaluated 28 unrelated patients with clinical suspicion of HNF1B mutation because of the concomitant presence of diabetes mellitus (DM) or prediabet
Arch. Endocrinol. Metab.. Publicado em: 02/05/2019
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4. Vagotomy ameliorates islet morphofunction and body metabolic homeostasis in MSG-obese rats
The parasympathetic nervous system is important for β-cell secretion and mass regulation. Here, we characterized involvement of the vagus nerve in pancreatic β-cell morphofunctional regulation and body nutrient homeostasis in 90-day-old monosodium glutamate (MSG)-obese rats. Male newborn Wistar rats received MSG (4 g/kg body weight) or saline [control (CTL
Braz J Med Biol Res. Publicado em: 24/02/2015
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5. Dieta hiperlipídica materna e pós-natal promove remodelamento adverso do fígado, pâncreas e tecido adiposo na prole / Maternal and postnatal high fat diet provoke adverse liver, pancreas and adipose tissue remodelling in offspring
A dieta hiperlipídica (high-fat, HF) materna durante a gestação e/ou lactação aumenta a susceptibilidade da prole para o desenvolvimento de doenças crônicas na fase adulta. Verificar a hipótese que a ingestão materna de dieta HF nos períodos críticos de desenvolvimento (gestação e/ou lactação) predispõe à doença não alcoólica do fígado g
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 21/07/2010
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6. Alteração do ciclo menstrual na adolescência: manifestação precoce da Síndrome Metabólica? / Alteration on menstrual cycle in adolescence: early manifestation of Metabolic Syndrome?
Evidences have appeared throughout the last decade that the metabolic syndrome(MS) (increasingly reported among teens) begins in intra-uterine life and its signs and symptoms are already present in adolescence. Nevertheless, specific diagnostic criteria for this age group are missing. The menstrual cycle represents the result of the normal functioning not on
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/07/2010
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7. Agonistas PPAR (Rosiglitazona, Bezafibrato e Fenofibrato) e alterações bioquímicas e estruturais em órgãos-alvo de camundongos C57BL/6 alimentados com dieta hiperlipídica rica em sacarose / PPAR agonists (Rosiglitazone, Bezafibrate and Fenofibrate) and biochemical and structural changes in target organs of C57BL/6 mice fed a high-fat high-sucrose diet
This work aimed to evaluate the effect of peroxisome proliferator-activated receptor (PPAR) agonists (rosiglitazone, fenofibrate and bezafibrate) on lipid and glucose metabolism, body mass, and adipose and pancreatic tissue morphology in a model of diet-induced type 2 diabetes and overweight in mice. Two-month-old male C57BL/6 mice were fed a standard chow (
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 07/06/2010
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8. Modulação da secreção de insulina por estresse oxidativo induzido em ilhotas pancreáticas de animais submetidos à desnutrição protéica / Oxidative stress modulation of insulin secretion in protein undernourished rats pancreatic islet
Protein malnutrition induces pacreatic B-cells molecular alterations, reducing insulin secretion. It has been recently demonstrated that redox status may control insulin secretion under physiological conditions. However, protein malnutrition effects in redox modulation of insulin secretion is unknown. Thus, our aim was to evaluate oxidative stress impact upo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/12/2009
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9. Dendritic cells (DC) generation from peripheral blood mononuclear cells obtained from jaundiced patients with pancreatic adenocarcinoma. / Análise de células mononucleares mantidas em cultura em meio propício para geração de células dendríticas obtidas de pacientes com câncer de pâncreas.
Pancreatic adenocarcinoma (PAdc) is an aggressive malignancy with poor prognosis, urging for improved or new therapeutic strategies. DC-based vaccination is one of such promising approaches. DC are the most potent antigen-presenting cells and central to the induction and maintenance of an immune response. However, in cancer patients DC generation and functio
Publicado em: 2008
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10. Investigação da associação entre os polimorfismos dos genes : MBL2, TGF-B1 e CD14 com a gravidade do quadro pulmonar na fibrose cistica / Investigation of the association between polymorphisms of MBL2, TGFB1 and CD4 genes with lung diseases severity in cystic fibrosis
Cystic fibrosis is a genetic alteration characterized mainly by pancreatic and pulmonary manifestations. The genotype-phenotype correlation in cystic fibrosis has been the subject of arduous studies. A correlation between cystic fibrosis and pancreatic insufficiency, as well as to the fact that the occurrence and severity of pulmonary manifestations are not
Publicado em: 2007
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11. Prolactina potencializa a secreção de insulina via formação do complexo SNARE em ilhotas pancreaticas / Prolactin modulates the insulin secretion by SNARE complex formation in neonatal rat islets
Prolactin induces maturation of insulin secretion in cultured neonatal rat islets. In this study, we investigated whether the improved secretory response to glucose caused by prolactin involves alteration in the expression, association and phosphorylation of several proteins that participate in these processes. Messenger RNA was extracted from neonatal rat i
Publicado em: 2006
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12. Prolactina induz aumento na expressão das proteinas SNARE e da sinaptotagmina 4 em ilhotas de ratos
The soluble N-ethylmaleimide-sensitive factor attached protein receptor (SNARE) molecules SNAP-25, syntaxin and VAMP-2 as well as synaptotagmins participate in the extrusion of insulin containing granules in pancreatic β -cells. During pregnancy and the perinatal periods of life, prolactin (PRL) and other lactogenic substances induce maturation of the s
Publicado em: 2004