Nevoid Basal Cell Carcinoma Syndrome
Mostrando 1-7 de 7 artigos, teses e dissertações.
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1. Reclassification and treatment of odontogenic keratocysts: A cohort study
Abstract: The odontogenic keratocyst (OKC) is a recurrent cyst that has been recently reclassified from an odontogenic tumor to an odontogenic cyst. The aim of the present study was to investigate its treatment and address issues related to its association with nevoid basal cell carcinoma syndrome (NBCCS). Lesions from the cohort of patients included in the
Braz. oral res.. Publicado em: 18/12/2017
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2. Syndrome in question: Gorlin-Goltz syndrome
Abstract: The Nevoid Basal Cell Carcinoma Syndrome (NBCCS) is an uncommon disorder caused by a mutation in Patched, tumor suppressor gene. It is mainly characterized by numerous early onset basal cell carcinomas, odontogenic cysts of jaw and skeletal abnormalities. Due to the wide clinical spectrum, treatment and management of its modalities are not standard
An. Bras. Dermatol.. Publicado em: 2016-08
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3. Keratocystic odontogenic tumor related to nevoid basal cell carcinoma syndrome: clinicopathological study
AIM: To assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with nevoid basal cell carcinoma syndrome (NBCCS) in a single Brazilian institution. METHODS: After histopathological analyses of KCOT related to NBCCS, the medical charts of 14 patients were assessed. These patients presented a total of 31 primary a
Braz. J. Oral Sci.. Publicado em: 2013-03
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4. Study of surgical treatment of keratocystic odontogenic tumors associated or not to the nevoid basal cell carcinoma syndrome and analysis of recurrence-free period / Estudo da terapêutica cirúrgica dos tumores odontogênicos queratocísticos associados ou não à síndrome do carcinoma nevóide de células basais e análise do tempo livre de recorrência
O tumor odontogênico queratocístico (TOQ) é uma neoplasia cística benigna originada de remanescentes epiteliais da odontogênese, que se destaca pela alta recorrência e eventual associação com a síndrome do carcinoma nevóide de células basais (SCNCB). O presente estudo buscou responder questionamentos relacionados à sua terapêutica cirúrgica e s
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 12/04/2012
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5. Avaliação dos parâmetros clínico, histopatológico e imunoistoquímico dos tumores odontogênicos queratocísticos associados ou não à Síndrome do Carcinoma basocelular nevóide / Evaluation of clinical, histopathological and immunohistochemistry parameters of Keratocystic Odontogenic Tumor associated or not with Nevoid Basal Cell Carcinoma Syndrome
Introdução. O Tumor Odontogênico Queratocístico (TOQC) é uma lesão de origem odontogênica que se apresenta exclusivamente nos ossos gnáticos e possui alto potencial de agressividade local. Pode estar associado à Síndrome do Carcinoma Nevóide Basocelular (SCNBC), que se caracteriza por apresentar inúmeras alterações de desenvolvimento, múltiplo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/10/2011
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6. No evidence for mutations in exons 1, 8 and 18 of the patched gene in sporadic skin lesions of Brazilian patients
There is strong evidence that the patched (PTCH) gene is a gene for susceptibility to the nevoid basal cell carcinoma syndrome. PTCH has also been shown to mutate in both familial and sporadic basal cell carcinomas. However, mutations of the gene seem to be rare in squamous cell carcinomas. In order to characterize the role of the gene in the broader spectru
Brazilian Journal of Medical and Biological Research. Publicado em: 2003-04
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7. High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum
Recently, hptc, a human gene homologous to the Drosophila segment polarity gene patched (ptc), has been implicated in the nevoid basal-cell carcinoma (BCC) syndrome, and somatic mutations of hptc also have been found in sporadic BCCs, the most frequent cancers found in the white population. We have analyzed the hptc gene, postulated to be a tumor suppressor
The National Academy of Sciences.