Neuropeptide Y
Mostrando 1-12 de 195 artigos, teses e dissertações.
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1. Influence of Neuropeptide Y and Neuropeptide Y 2 Receptor Variants in Acute Coronary Syndrome
Abstract Background The neuropeptide Y (NPY) is one of the most abundant neurotransmitters in the nervous system. NPY acts as a potent stimulator of angiogenesis, inflammation, and adipogenesis, through the NPY 2 receptor (NPY2R). Changes in the NPY signaling pathway have been linked to Acute Coronary Syndrome (ACS). Objectives The purpose of this study
International Journal of Cardiovascular Sciences. Publicado em: 2022
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2. Modulation of neuropeptide Y levels is impaired in crack withdrawal patients
Abstract Introduction The dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has a key role in drug addiction susceptibility. In addition to the well-known relationship between cortisol and the HPA axis, other molecules are involved with stress response and could modify the HPA activation, such as the neuropeptide Y (NPY), which has anxiolytic
Trends Psychiatry Psychother.. Publicado em: 2020-06
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3. COVID-19 and Assisted Reproduction: A Point of View on the Brazilian Scenario
Abstract Introduction The dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has a key role in drug addiction susceptibility. In addition to the well-known relationship between cortisol and the HPA axis, other molecules are involved with stress response and could modify the HPA activation, such as the neuropeptide Y (NPY), which has anxiolytic
Rev. Bras. Ginecol. Obstet.. Publicado em: 2020-06
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4. Relations of neuropeptide Y and heme oxygenase-1 expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy
Abstract Purpose: To investigate the relations of neuropeptide Y (NPY) and heme oxygenase-1 (HO-1) expressions with fetal brain injury in rats with intrahepatic cholestasis of pregnancy (ICP). Methods: Sixty rats pregnant for 15 days were randomly divided into experimental and control groups. The ICP model was established in experimental group. On the 21
Acta Cir. Bras.. Publicado em: 06/05/2019
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5. Determinants of body weight regulation in humans
ABSTRACT Body weight is regulated by the ability of hypothalamic neurons to orchestrate behavioral, endocrine and autonomic responses via afferent and efferent pathways to the brainstem and the periphery. Weight maintenance requires a balance between energy intake and energy expenditure. Although several components that participate in energy homeostasis have
Arch. Endocrinol. Metab.. Publicado em: 23/02/2016
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6. Neuropeptide Y, substance P, and human bone morphogenetic protein 2 stimulate human osteoblast osteogenic activity by enhancing gap junction intercellular communication
Bone homeostasis seems to be controlled by delicate and subtle “cross talk” between the nervous system and “osteo-neuromediators” that control bone remodeling. The purpose of this study was to evaluate the effect of interactions between neuropeptides and human bone morphogenetic protein 2 (hBMP2) on human osteoblasts. We also investigated the effects
Braz J Med Biol Res. Publicado em: 13/02/2015
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7. Estradiol-induced hypophagia is associated with the differential mRNA expression of hypothalamic neuropeptides
Estradiol participates in the control of energy homeostasis, as demonstrated by an increase in food intake and in body weight gain after ovariectomy in rats. In the present study, female Wistar rats (200-230 g, N = 5-15 per group), with free access to chow, were individually housed in metabolic cages. We investigated food intake, body weight, plasma leptin l
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-08
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8. Avaliação da expressão de neuropeptídeo y em hipocampo de ratos com epilepsia induzida pela pilocarpina. / Evaluation of the expression of neuropeptídeo y in hipocampo of rats with induced epilepsy for the pilocarpina.
O neuropeptídeo Y foi descoberto na década de 80 e é constituído por 36 aminoácidos. O objetivo deste estudo foi a avaliação da expressão do RNA mensageiro do neuropeptídeo Y (NPY) em hipocampos de ratos epiléticos. Ratos Wistar machos foram submetidos ao modelo de epilepsia induzido por pilocarpina. Os hipocampos foram removidos 6 h (fase aguda),
Publicado em: 2010
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9. Estudo da associação entre ansiedade e susceptibilidade à epilepsia do lobo temporal em ratos / Association between anxiety and susceptibility to temporal lobe epilepsy in rats
Subjects with temporal lobe epilepsy (TLE) present an heterogeneous response to pharmacotherapy. This heterogeneity results from physiological differences that might be caused by preexisting factors such as genetic ones. In many patients with TLE, the prognostic for controling the seizures is satisfactory. A significant proportion of individuals however do n
Publicado em: 2010
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10. Efeito da leptina e da nutrição sobre o perfil de expressão de genes hipotalâmicos em novilhas zebuínas (Bos taurus indicus) no início da puberdade / Leptin and nutrition effect on gene expression profile of hypothalamic genes in Bos taurus indicus heifers on the onset of puberty: an experimental study
Investigou-se o efeito da leptina exógena e do maior consumo de energia, sobre o padrão da expressão de genes no hipotálamo de novilhas zebuínas; de modo a elucidar o mecanismo de sinalização da leptina no hipotálamo e os genes responsáveis pela obtenção da puberdade. Trinta e seis novilhas não púberes, e com idade entre 18 e 20 meses, foram div
Publicado em: 2010
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11. Association of hypotalamic POMC, NPY and IRS2 with feeding behavior in norma and overweight Wistar rats / Associação do PMOC, NPY e IRS2 hipotalâmicos com padrões de comportamento alimentar em ratos wistar normais e sobrepeso
The feeding behavior of a specie is determined by a group of phylogenetic, ontogenetic, and epigenetic features, and regulated by internal and external factors to the organism. The natural phenomena that govern life in our planet are mainly periodic, and the food stocks is not an exception. Each harvest is followed by a time between harvests, and this rhythm
Publicado em: 2009
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12. Leptin and hypothalamic gene expression in early- and late-maturing Bos indicus Nellore heifers
We investigated wether early-maturing or late-maturing Bos indicus Nellore heifers produced more leptin mRNA in adipose tissues and altered expression of hypothalamic genes related to leptin signaling. Six prepubertal and six pubertal heifers aged about 34 months and weighing 280 kg to 300 kg each were selected from a population of 100 Nellore heifers. Real-
Genetics and Molecular Biology. Publicado em: 2008