Neuron Specific Enolase
Mostrando 1-12 de 52 artigos, teses e dissertações.
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1. State biomarkers for Machado Joseph disease: Validation, feasibility and responsiveness to change
Abstract Machado-Joseph disease (SCA3/MJD) is the most common spinocerebellar ataxia worldwide, and particularly so in Southern Brazil. Due to an expanded polyglutamine at ataxin-3, SCA3/MJD presents a relentless course with no current disease modifying treatment. Clinical scales used to measure SCA3/MJD progression present moderate effect sizes, a major dra
Genet. Mol. Biol.. Publicado em: 10/06/2019
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2. Neuron-specific enolase as biomarker for possible neuronal damage in dogs with distemper vírus
RESUMO: Enolase neuronal específica (NSE) é um biomarcador de lise de neurônios, que demonstra estabilidade em fluidos extracelulares como sangue e líquido cerebrospinal. Para o conhecimento dos autores, não há informações de pesquisa que comparem o uso de NSE em cães com e sem encefalite, evidenciando a importância desse biomarcador para detectar
Pesq. Vet. Bras.. Publicado em: 2019-01
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3. Multipotent male germline stem cells (mGSCs) from neonate porcine testis
ABSTRACT Spermatogonial stem cells (SSCs) are the foundation of spermatogenesis, during which unlimited spermatozoa is produced daily derived from SSCs in the testis throughout life of the male. Germline stem (GS) cells can be isolated from spermatogonia, which shared the characteristics of SSCs and embryonic stem cells (ESCs), and can be passaged stably in
Braz. arch. biol. technol.. Publicado em: 08/03/2016
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4. Lack of association of S100β and neuron-specific enolase with mortality in critically ill patients
Objective: To evaluate the relationship between brain damage biomarkers and mortality in the intensive care unit (ICU). Methods: The sample comprised 70 patients admitted to an ICU. Blood samples were collected from all patients on ICU admission, and levels of S100β and neuron-specific enolase (NSE) were determined by ELISA. Results: Acute Physiologic
Rev. Bras. Psiquiatr.. Publicado em: 2013-09
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5. Diagnostic work-up of gastroenteropancreatic neuroendocrine tumors
Neuroendocrine tumors are a heterogeneous group of malignancies that present a diagnostic challenge. The majority of patients (more than 60%) present with metastatic disease at diagnosis. The diagnosis is based on histopathology, imaging, and circulating biomarkers. The histopathology should contain specific neuroendocrine markers such as chromogranin A, syn
Clinics. Publicado em: 2012
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6. Valor da enolase específica do neurônio como indicador de prognóstico pós-parada cardiorrespiratória / Serum neuron-specific eolase as a prognostic marker after a cardiac arrest
JUSTIFICATIVA E OBJETIVOS: A parada cardíaca é um estado de grave hipoperfusão cerebral. Os pacientes que sobrevivem a uma reanimação cardiorrespiratória estão sob grande risco de vir a morrer ou desenvolver lesão cerebral incapacitante, inclusive estado vegetativo persistente. Uma definição precoce do prognóstico desses pacientes tem implicaçõe
Publicado em: 2010
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7. Brain injury markers (S100B and NSE) in chronic cocaine dependents = Marcadores de lesão cerebral (S100B e NSE) em dependentes crônicos de cocaína
Objetivo: Estudos têm demonstrado sinais de lesão cerebral causadas por diferentes mecanismos em usuários de cocaína. A enolase sérica neurônio-específica e a proteína S100B são consideradas marcadores bioquímicos específicos de lesão neuronal e glial. Este estudo objetivou comparar os níveis sangüíneos de S100B e enolase sérica neurônio-esp
Publicado em: 2010
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8. Serum neuron-specific enolase as early predictor of outcome after in-hospital cardiac arrest : a cohort study
Introduction Outcome after cardiac arrest is mostly determined by the degree of hypoxic brain damage. Patients recovering from cardiopulmonary resuscitation are at great risk of subsequent death or severe neurological damage, including persistent vegetative state. The early definition of prognosis for these patients has ethical and economic implications. The
Publicado em: 2010
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9. Serum levels of S100B and NSE proteins in Alzheimer’s disease patients
Background: Alzheimer’s disease is the most common dementia in the elderly, and the potential of peripheral biochemical markers as complementary tools in the neuropsychiatric evaluation of these patients has claimed further attention. Methods: We evaluated serum levels of S100B and neuron-specific enolase (NSE) in 54 mild, moderate and severe Alzheimer’s
Publicado em: 2010
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10. Avaliação de parâmetros neuroquímicos em fatias de hipocampo de rato submetidas à privação de oxigênio e glicose
Mesmo a isquemia sendo a terceira causa de morte em países industrializados, os mecanismos relacionados a esta doença ainda continuam polêmicos e obscuros. Utilizou-se a técnica de privação de oxigênio e glicose (OGD) em fatias do hipocampo de rato para investigar parâmetros mitocondriais, neurais, astrogliais e metabólicos no período de isquemia e
Publicado em: 2010
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11. Use of neuron-specific enolase for assessing the severity and outcome of neurological disorders in patients
Neuron-specific enolase (NSE) is a glycolytic enzyme present almost exclusively in neurons and neuroendocrine cells. NSE levels in cerebrospinal fluid (CSF) are assumed to be useful to estimate neuronal injury and clinical outcome of patients with serious clinical manifestations such as those observed in stroke, head injury, anoxic encephalopathy, encephalit
Brazilian Journal of Medical and Biological Research. Publicado em: 2004-01
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12. Immunohistochemical investigation of neuronal injury in cerebral cortex of cobra-envenomed rats
The immunohistochemical expression of neuron-specific enolase, NSE (a cytoplasmic glycolytic enzyme of the neurons), synaptophysin, SYN (a major membrane glycoprotein of synaptic vesicles), and Bcl-2 (anti-apoptotic protein) were determined in cerebral cortex of rats envenomed with neurotoxic venom from Egyptian cobra. Male rats were intramuscularly (IM) inj
Journal of Venomous Animals and Toxins including Tropical Diseases. Publicado em: 2004