Nanostructured Lipid Carriers
Mostrando 1-8 de 8 artigos, teses e dissertações.
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1. Nanostructured Lipid Carriers Loaded with 17-α-Estradiol Accumulate into Hair Follicles
To improve 17-α-estradiol targeting in alopecia treatment, a formulation of nanostructured lipid carrier (NLC) prepared by the sonication method was developed. The physicochemical characterization showed an average diameter of 96 ± 15 nm and the average zeta potential of -17 ± 6 mV. In addition, the encapsulation efficiency (EE) of 17-α-estradiol, assess
J. Braz. Chem. Soc.. Publicado em: 2020-07
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2. Colombian propolis as starting material for the preparation of nanostructured lipid carriers
ABSTRACT The value of propolis is scientifically and commercially measured through the content of biologically active molecules as phenolic compounds and flavonoids; on the other hand, a high percentage of waxes in the propolis composition makes it a substandard beekeeping product. Colombian propolis is characterized by a high content of waxes; however, this
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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3. Validation of a Chromatographic Analytical Method for Quantification of Benznidazole Incorporated in Nanostructured Lipid Formulations
Benznidazole (BNZ) has been employed in the treatment of Chagas disease; however, its low water solubility is a drawback, which can be overcome by incorporating BZN within nanostructured systems. The aim of this work was to validate a chromatographic method for determination of BZN incorporated in nanoemulsions (NE) and nanostructured lipid carriers (NLC). T
J. Braz. Chem. Soc.. Publicado em: 2017-02
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4. SISTEMAS CARREADORES LIPÍDICOS NANOESTRUTURADOS PARA IVERMECTINA E METOPRENO VISANDO CONTROLE DE PARASITAS
The study of characteristics of nanoscale structures and applications now has great interest of researchers from different areas. In this regard, lipid carriers can improve the bioavailability of drugs and the reduction of possible toxicological effects. Thus, the development of nanostructured systems for the agricultural sector, aimed at combating parasites
Quím. Nova. Publicado em: 2016-11
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5. Desenvolvimento e caracterização de nanopartículas lipídicas contendo topotecano / Development and characterization of lipid nanoparticles containing topotecan
O cloridrato de topotecano (TPT), derivado semi-sintético hidrofílico da camptotecina, é um fármaco antineoplásico inibidor da topoisomerase I. A encapsulação do TPT em nanocarreadores pode protegê-lo da inativação no pH plasmático, além de contornar o problema da resistência celular mediada pela glicoproteína-P (P-gp). No presente trabalho for
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/10/2010
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6. Desenvolvimento e caracterização de nanopartículas lipídicas contendo topotecano / Development and characterization of lipid nanoparticles containing topotecan
O cloridrato de topotecano (TPT), derivado semi-sintético hidrofílico da camptotecina, é um fármaco antineoplásico inibidor da topoisomerase I. A encapsulação do TPT em nanocarreadores pode protegê-lo da inativação no pH plasmático, além de contornar o problema da resistência celular mediada pela glicoproteína-P (P-gp). No presente trabalho for
Publicado em: 2010
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7. Carreador lipÃdico nanoestruturado à base de cera de carnaÃba: desenvolvimento, caracterizaÃÃo e uso na encapsulaÃÃo de benzofenona-3
Solid lipid nanoparticles made of pure lipids (SLN) or a mixture of solid and liquid lipids (NLC) have been proposed as a category of carriers for cosmetic ingredients of current and growing interest due to a number of advantages compared to conventional formulations. Natural waxes are considered lipid matrices of great potential for the production of topica
Publicado em: 2009
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8. Evaluation of alternative strategies to optimize ketorolac transdermal delivery
In the present study, 2 alternative strategies to optimize ketorolac transdermal delivery, namely, prodrugs (polyoxyethylene glycol ester derivatives, I–IV) and nanostructured lipid carriers (NLC) were investigated. The synthesized prodrugs were chemically stable and easily degraded to the parent drug in human plasma. Ketorolac-loaded NLC with high drug co
Springer-Verlag.