Nanoemulsion
Mostrando 1-12 de 68 artigos, teses e dissertações.
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1. Linseed Oil Nanoemulsion with Pluronic® F127 Loaded with Betulinic Acid: Preparation, Rheology, MTT Assay and in vitro Release Kinetics
The main objective of this work was to develop a nanoemulsion based on linseed oil and betulinic acid, stabilized with Pluronic F127 and polyglycerol polyricinoleate, for anticancer applications. The nanoemulsions were synthesized by ultrasound and evaluated for in vitro cytotoxicity, particle size, polydispersity index, zeta potential, morphology, encapsula
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Application of a New Validated HPLC-PDA Method for Simultaneous Determination of Curcumin and Melatonin in Hyaluronic Acid-Coated Nanoemulsions
In this study, a high-performance liquid chromatography with photodiode array detector (HPLC-PDA) method was developed and validated to simultaneously determine curcumin (CUR) and melatonin (MEL) in hyaluronic acid-coated nanoemulsions, a novel targetable delivery system to CD44 receptors overexpressed in many types of tumors. Chromatographic analyses were p
J. Braz. Chem. Soc.. Publicado em: 2020-03
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3. Nanoemulsion containing caffeine for cellulite treatment: characterization and in vitro evaluation
The Ginoide Hydrolipodystrophy (GHLD), commonly known as cellulite, occurs in 80-90% of the female population after the puberty period and comes from a metabolic modification in the cutaneous adipose tissue. Caffeine has been used in topical formulations due to its lipolytic action. We studied a nanoemulsion (F3) containing caffeine with two surfactants (ole
Braz. J. Pharm. Sci.. Publicado em: 24/10/2019
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4. FORMULATION AND CHARACTERIZATION OF ULTRASOUND-ASSISTED NANOEMULSIONS CONTAINING PALM OIL (Elaeis guineensis Jacq) IN WATER
Abstract This study aimed to optimize ultrasound-assisted palm oil-in-water nanoemulsions. The influence of hydrophilic-lipophilic balance (HLB), oil and surfactants concentrations, ultrasound intensity and processing time were investigated by means of two experimental designs. Desirability profiles were applied to detect the optimal conditions for preparing
Braz. J. Chem. Eng.. Publicado em: 30/09/2019
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5. Anthelmintic effect of Cymbopogon citratus essential oil and its nanoemulsion on sheep gastrointestinal nematodes
Resumo A resistência anti-helmíntica estimulou a busca por estratégias de controle de nematoides gastrintestinais, incluindo óleos essenciais livres ou em nanoemulsão. Este estudo avaliou a eficácia anti-helmíntica do óleo essencial de Cymbopogon citratus (OECc) e da nanoemulsão do óleo essencial de C. citratus (nOECc). Análises físico-químicas
Rev. Bras. Parasitol. Vet.. Publicado em: 29/08/2019
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6. Physicochemical characterization and evaluation of in vitro and in vivo toxicity of goldenberry extract nanoemulsion
RESUMO: Nanoemulsão óleo/água (O/A) contendo extrato de goldenberry foi elaborada utilizando método de banho ultrassônico de alta energia. A caracterização físico-química da formulação foi realizada pela determinação do pH, diâmetro médio de gotas, índice de polidispersão (PDI) e potencial zeta. A toxicidade das nanoemulsões foi avaliada u
Cienc. Rural. Publicado em: 22/08/2019
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7. Preparation of beta-carotene nanoemulsion and evaluation of stability at a long storage period
Abstract Carotenoids have a low solubility in water, and therefore their incorporation in foods is impaired. The nanoemulsions are able to protect these compounds and enhance bioavailability. The objective of this study was to develop nanoemulsions with added beta-carotene, evaluating the influence of process variables and the stability at a long storage per
Food Sci. Technol. Publicado em: 15/07/2019
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8. Nanotechnology for the treatment of deep endometriosis: uptake of lipid core nanoparticles by LDL receptors in endometriotic foci
OBJECTIVE: Rapidly dividing cells in multiple types of cancer and inflammatory diseases undergo high low density lipoprotein (LDL) uptake for membrane synthesis, and coupling an LDL-like nanoemulsion, containing lipid nanoparticles (LDE) to a chemotherapeutic agent efficiently targets these cells without significant systemic effects. This was a prospective
Clinics. Publicado em: 10/07/2019
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9. Anti-adipogenic effect of a turmeric extract-loaded nanoemulsion in 3T3-L1 preadipocytes and high fat diet-fed mice
Abstract We investigated the effects of a turmeric extract-loaded nanoemulsion (TENE) on lipid accumulation in 3T3-L1 adipocytes and in mice fed a high fat diet (HFD). The accumulation of intracellular lipid in 3T3-L1 adipocytes was significantly inhibited by TENE, according to Oil red O and Nile Red staining. This inhibitory effect of TENE on adipocyte diff
Food Sci. Technol. Publicado em: 27/06/2019
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10. PREPARATION AND CHARACTERIZATION OF A QUERCETIN-TETRAETHYL ETHER-BASED PHOTOPROTECTIVE NANOEMULSION
Although Quercetin absorbs in the UVA/UVB electromagnetic region, it is limited for applications as a UV filter due to its low lipophilicity and capacity to penetrate the epidermis. In order to overcome this limitation, we synthetized and evaluated the photo protective properties of a derivative obtained from Quercetin. The derivative was prepared by alkylat
Quím. Nova. Publicado em: 27/05/2019
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11. Nanoemulsion containing essential oil from Xylopia ochrantha Mart. produces molluscicidal effects against different species of Biomphalaria (Schistosoma hosts)
BACKGROUND This work describes a chemical study of the essential oil from leaves of Xylopia ochrantha, an endemic Annonaceae species from Brazil, and its activity against Biomphalaria species. Considering its poor solubility in aqueous medium, the essential oil was nanoemulsified to evaluate its action on controlling some mollusc species of genus Biomphala
Mem. Inst. Oswaldo Cruz. Publicado em: 08/04/2019
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12. Physicochemical Characterizations and Antioxidant Property of Copaiba Oil Loaded into SNEDDS Systems
Self-nanoemulsion drug delivery systems (SNEDDS) represent a potential carrier to improve solubility and bioavailability of health care products. In this sense, copaiba oil (CO) loaded on cosurfactant-free SNEDDS formulations (CO-SNEDDS) were obtained by using phase diagram performed on different concentrations of constituents (oil, surfactant and water). Th
J. Braz. Chem. Soc.. Publicado em: 2019-02