N Acihidrazone Pirazinic
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1. Evaluation of antinociceptive and anti-inflammatory activity of new derivatives N-acilidrazônicos (NAH) pyrazine. / Avaliação da atividade antinociceptiva e antiinflamatória de novos derivados N-acilidrazônicos (NAH) pirazínicos.
A new series of derivatives N-acihidrazone (NAH) pirazinic was rationally planned be applied the strategy of simplification molecular on the unit quinoxalinic of prototype LASSBio-1018, identified as a potent anti-inflammatory and analgesic in LASSBio designed by application the biososterism of rings on LASSBio-319. The new series of 21 derivatives were synt
Publicado em: 2009