Myosin
Mostrando 1-12 de 1566 artigos, teses e dissertações.
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1. Retinoic acid induces differentiation of cochlear neural progenitor cells into hair cells
Resumo Introdução: As células progenitoras da orelha interna têm potencial para diferenciação multidirecional. O ácido retinoico é uma condição importante para o desenvolvimento da orelha interna. O bloqueio da via de sinalização do ácido retinoico no órgão de Corti pode reduzir significativamente o número de células ciliadas. Portanto, acr
Brazilian Journal of Otorhinolaryngology. Publicado em: 2022
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2. Essential oil of the leaves of Eugenia sulcata preserve myocardial contractility and does not present immunotoxicity
The essential oil of the leaves of Eugenia sulcata, in the Myrtaceae family, has a demonstrated antihypertensive effect, but its effects on heart muscle and its toxicity have not yet been elucidated. Little chemical or biological data are available for E. sulcata, whether emphasizing the beneficial effects or the pharmacological security of this species. Thi
Braz. J. Pharm. Sci.. Publicado em: 30/09/2019
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3. YAP activation promotes the transdifferentiation of cardiac fibroblasts to myofibroblasts in matrix remodeling of dilated cardiomyopathy
Yes-associated protein (YAP) is an important regulator of cellular proliferation and transdifferentiation. However, little is known about the mechanisms underlying myofibroblast transdifferentiation in dilated cardiomyopathy (DCM). We investigated the role of YAP in the pathological process of cardiac matrix remodeling. A classic model of DCM was established
Braz J Med Biol Res. Publicado em: 23/11/2018
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4. Effect of setting on the gelling properties of a protein concentrate from giant squid ( Dosidicus gigas) mantle
Abstract Different studies on obtaining protein concentrates or surimi from giant squid ( Dosidicus gigas) have reported that soft gels are obtained in comparison with other fish species. Therefore, the aim of this research was to investigate the effect of the setting (30 and 60 °C, for 0, 30, 60, and 90 min) on the gelling capacity as a possible alternati
Food Sci. Technol. Publicado em: 16/04/2018
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5. Cardiac protein expression patterns are associated with distinct inborn exercise capacity in non-selectively bred rats
In the present study, we successfully demonstrated for the first time the existence of cardiac proteomic differences between non-selectively bred rats with distinct intrinsic exercise capacities. A proteomic approach based on two-dimensional gel electrophoresis coupled to mass spectrometry was used to study the left ventricle (LV) tissue proteome of rats wit
Braz J Med Biol Res. Publicado em: 11/01/2018
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6. Changes in serum cardiac myosin light chain 1 levels in children with fulminant myocarditis during continuous blood purification
Summary Objective: To investigate the changes in serum cardiac myosin light chain 1 (CMLC-1) levels in children with fulminant myocarditis (FM) during continuous blood purification (CBP), as well as to analyze its correlation with other laboratory indexes. Method: Twenty-four (24) children with FM who underwent CBP were enrolled. Before and during treatmen
Rev. Assoc. Med. Bras.. Publicado em: 2017-10
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7. The adductor pectoral fin muscle of Micropogonias furnieri (Perciformes: Sciaenidae): a morphological and histochemical study
ABSTRACT The adductor pectoral fin muscle in post-spawning females of the white croaker Micropogonias furnieri (Desmarest, 1823) is described from a morphological, histochemical and morphometric perspectives. A description of the morphological characteristics was conducted after dissections in different layers, down to the deep layer. Five muscles were found
Zoologia (Curitiba). Publicado em: 15/12/2016
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8. Evaluation of different software tools for deconvolving differential scanning calorimetry thermograms of salted beef
Abstract The objective of this research was to evaluate the ability and efficiency of different software tools for the deconvolution of DSC thermograms of protein denaturation in salted beef. The salted samples were obtained by immersing beef pieces in NaCl solutions with concentrations of 20, 50, 100 and 330 g NaCl L-1 of water for 48 hours at 10 °C. The r
Food Sci. Technol. Publicado em: 17/11/2016
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9. Transplantation and survival of mouse inner ear progenitor/stem cells in the organ of Corti after cochleostomy of hearing-impaired guinea pigs: preliminary results
In mammals, damage to sensory receptor cells (hair cells) of the inner ear results in permanent sensorineural hearing loss. Here, we investigated whether postnatal mouse inner ear progenitor/stem cells (mIESCs) are viable after transplantation into the basal turns of neomycin-injured guinea pig cochleas. We also examined the effects of mIESC transplantation
Braz J Med Biol Res. Publicado em: 18/03/2016
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10. α-Smooth Muscle Actin and ACTA2 Gene Expressions in Vasculopathies
ABSTRACT α-smooth muscle actin, encoded by ACTA2 gene, is an isoform of the vascular smooth muscle actins, typically expressed in the vascular smooth muscle cells contributing to vascular motility and contraction. ACTA2 gene mutations cause a diversity of diffuse vasculopathies such as thoracic aortic aneurysms and dissections as well as occlusive vascular
Braz. J. Cardiovasc. Surg.. Publicado em: 2015-12
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11. Numeric reconstruction of 2D cellular actomyosin network from substrate displacement
Introduction: One of the fundamental structural elements of the cell is the cytoskeleton. Along with myosin, actin microfilaments are responsible for cellular contractions, and their organization may be related to pathological changes in myocardial tissue. Due to the complexity of factors involved, numerical modeling of the cytoskeleton has the potential to
Res. Biomed. Eng.. Publicado em: 27/11/2015
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12. Modulatory effects of taurine on jejunal contractility
Taurine (2-aminoethanesulfonic acid) is widely distributed in animal tissues and has diverse pharmacological effects. However, the role of taurine in modulating smooth muscle contractility is still controversial. We propose that taurine (5-80 mM) can exert bidirectional modulation on the contractility of isolated rat jejunal segments. Different low and high
Braz J Med Biol Res. Publicado em: 14/10/2014