Motor Delays
Mostrando 13-24 de 33 artigos, teses e dissertações.
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13. Constancy of central conduction delays during development in man: investigation of motor and somatosensory pathways.
1. A cross-sectional study has been performed on 457 normal subjects to determine changes in conduction delays with age in central and peripheral motor and somatosensory pathways to the upper limb. 2. Electromagnetic stimulation was used to investigate central and peripheral conduction in motor pathways from the cortex to biceps brachii and hypothenar muscle
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14. Malignant spinal cord compression: prospective study of delays in referral and treatment
Objectives: To examine the delay in presentation, diagnosis, and treatment of malignant spinal cord compression and to define the effect of this delay on motor and bladder function at the time of treatment.
British Medical Journal.
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15. Pathophysiological mechanisms in cerebral palsy.
To investigate some of the pathophysiological mechanisms in cerebral palsy, surface electromyograms (EMG) were recorded from pairs of flexor/extensor muscles during both voluntary and passive flexion/extension of upper and lower limbs of 20 patients. Elbow, knee, or ankle joint angles were measured simultaneously, as well as the force required to flex/extend
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16. Organization of motor units following cross-reinnervation of antagonistic muscles in the cat hind limb.
Peripheral reorganization of nerve and muscle properties was studied following misdirection of regenerating axons to foreign muscles. The tibial nerve, which innervates all of the distal extensor muscles, was cross-united with the common peroneal nerve, which innervates all of the distal flexor muscles, in one hind limb of seven 2-6 month old cats. After 18-
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17. Motoneuron survival is promoted by specific exercise in a mouse model of amyotrophic lateral sclerosis
Several studies using transgenic mouse models of familial amyotrophic lateral sclerosis (ALS) have reported a life span increase in exercised animals, as long as animals are submitted to a moderate-intensity training protocol. However, the neuroprotective potential of exercise is still questionable. To gain further insight into the cellular basis of the exer
Blackwell Science Inc.
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18. Temporal Characteristics of the Predictive Synchronous Firing Modeled by Spike-Timing-Dependent Plasticity
When a sensory cue was repeatedly followed by a behavioral event with fixed delays, pairs of premotor and primary motor neurons showed significant increases of coincident spikes at times a monkey was expecting the event. These results provided evidence that neuronal firing synchrony has predictive power. To elucidate the underlying mechanism, here we argue s
Cold Spring Harbor Laboratory Press.
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19. Impulsiveness as a timing disturbance: neurocognitive abnormalities in attention-deficit hyperactivity disorder during temporal processes and normalization with methylphenidate
We argue that impulsiveness is characterized by compromised timing functions such as premature motor timing, decreased tolerance to delays, poor temporal foresight and steeper temporal discounting. A model illustration for the association between impulsiveness and timing deficits is the impulsiveness disorder of attention-deficit hyperactivity disorder (ADHD
The Royal Society.
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20. Extended Visual Simultaneity Thresholds in Patients With Schizophrenia
Clinical observations suggest that the experience of time phenomenology is disturbed in schizophrenia, possibly originating disorders in dynamic cognitive functions such as language or motor planning. We examined the subjective evaluation of temporal structure using an experimental approach involving judgments of simultaneity of simple, visually presented st
Oxford University Press.
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21. Translocation and specific cleavage of bacteriophage T7 DNA in vivo by EcoKI
Infection of Escherichia coli containing the type I restriction enzyme EcoKI by bacteriophage T7 0.3 mutants leads to restriction during the late stages of genome entry and during DNA replication. Patterns of cleavage in vivo suggest that some cutting occurs near the midpoint of two recognition sites, consistent with the idea that EcoKI translocates DNA bidi
The National Academy of Sciences.
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22. Neural representation of time in cortico-basal ganglia circuits
Encoding time is universally required for learning and structuring motor and cognitive actions, but how the brain keeps track of time is still not understood. We searched for time representations in cortico-basal ganglia circuits by recording from thousands of neurons in the prefrontal cortex and striatum of macaque monkeys performing a routine visuomotor ta
National Academy of Sciences.
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23. Over-expression of a human chromosome 22q11.2 segment including TXNRD2, COMT and ARVCF developmentally affects incentive learning and working memory in mice
Duplication of human chromosome 22q11.2 is associated with elevated rates of mental retardation, autism and many other behavioral phenotypes. However, because duplications cover 1.5–6 Mb, the precise manner in which segments of 22q11.2 causally affect behavior is not known in humans. We have now determined the developmental impact of over-expression of an
Oxford University Press.
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24. A motor programme for the initiation of forward-oriented movements in humans.
1. The EMG sequence activated before the initiation of a number of fast forward-oriented voluntary movements was analysed quantitatively in normal subjects. 2. The sequence consisted of an initial inhibitory component directed to the soleus motor nucleus, followed by a second excitatory one directed to the tibialis anterior (TA). 3. The spectrum of functiona