Microcystin Rr
Mostrando 1-12 de 15 artigos, teses e dissertações.
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1. Growth and microcystin production of a Brazilian Microcystis aeruginosa strain (LTPNA 02) under different nutrient conditions
Cyanobacteria are prokaryotic and photosynthetic organisms, which can produce a wide range of bioactive compounds with different properties; including a variety of toxic compounds, also known as cyanotoxins. In this work, we describe the isolation of seven cyanobacterial strains from two reservoirs in São Paulo State, Brazil. Seven different chemical varian
Rev. bras. farmacogn.. Publicado em: 2014-08
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2. Validação de método analítico livre de acetonitrila para análise de microcistinas por cromatografia líquida de alta eficiência
Blooms of cyanobacteria represent a public health risk due to their cyanotoxins such as microcystins. Liquid chromatography techniques to separate and quantify microcystins invariably use acetonitrile as the organic component of the mobile phase. The price and availability of acetonitrile together with its elevated toxicity encourage the validation of aceton
Quím. Nova. Publicado em: 2013
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3. Investigação da biossíntese de toxinas produzidas por cepas de cianobactérias / Investigation on the cyanobacterial strains toxins biossinthesys
A demanda crescente de água doce de boa qualidade são problemas atuais e mundiais, além do descaso com os dejetos lançados nos ambientes aquáticos que comprometem a qualidade dos recursos hídricos. Um dos parâmetros que atesta a potabilidade da água é a presença de cianobactérias e cianotoxinas. Cianobactérias são microrganismos procariontes aer
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 05/09/2011
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4. AVALIAÇÃO DA CAPACIDADE DE ADSORÇÃO DE DIFERENTES CARVÕES DERIVADOS DE MORINGA OLEIFERA NA REMOÇÃO DE MICROCISTINAS DE ÁGUAS CONTAMINADAS / AVALIAÇÃO DA CAPACIDADE DE ADSORÇÃO DE DIFERENTES CARVÕES DERIVADOS DE MORINGA OLEIFERA NA REMOÇÃO DE MICROCISTINAS DE ÁGUAS CONTAMINADAS
As cianobactérias constituem um grupo de organismos procariontes freqüentemente referidos como algas azuis. Estes organismos fazem parte do fitoplâncton natural, principalmente de água doce. No entanto, a sua proliferação excessiva leva ao acúmulo de grandes densidades de células na superfície da água, denominadas florações, que podem produzir um
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/03/2009
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5. Implementation of Real Time Quantitative PCR technique (qPCR) for the monitoring of Microcystis and potentially microcystin-producing genotypes / Implementação da técnica de PCR Quantitativa em Tempo Real (qPCR) para o monitoramento de Microcystis e genótipos potencialmente produtores de microcistinas
Florações de cianobactérias tóxicas em corpos dágua doce usados como fonte para o consumo humano, recreação e irrigação são freqüentes nos dias de hoje devido à eutrofização destes ambientes. O monitoramento de linhagens tóxicas é importante para a prevenção dos efeitos adversos causados por suas toxinas na saúde de humanos e animais. Mét
Publicado em: 2008
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6. Isolation and identification of eight microcystins from thirteen Oscillatoria agardhii strains and structure of a new microcystin.
Microcystins (cyclic heptapeptide hepatotoxins), isolated from 13 freshwater Oscillatoria agardhii strains from eight different Finnish lakes by high-performance liquid chromatography, were characterized by amino acid analysis, fast atom bombardment mass spectrometry (FABMS), and tandem FABMS (FABMS/collisionary-induced dissociation/MS). All strains produced
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7. The Abundance of Microcystin-Producing Genotypes Correlates Positively with Colony Size in Microcystis sp. and Determines Its Microcystin Net Production in Lake Wannsee
The working hypotheses tested on a natural population of Microcystis sp. in Lake Wannsee (Berlin, Germany) were that (i) the varying abundance of microcystin-producing genotypes versus non-microcystin-producing genotypes is a key factor for microcystin net production and (ii) the occurrence of a gene for microcystin net production is related to colony morpho
American Society for Microbiology.
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8. Rapid Isolation of a Single-Chain Antibody against the Cyanobacterial Toxin Microcystin-LR by Phage Display and Its Use in the Immunoaffinity Concentration of Microcystins from Water
A naïve (unimmunized) human semisynthetic phage display library was employed to isolate recombinant antibody fragments against the cyanobacterial hepatotoxin microcystin-LR. Selected antibody scFv genes were cloned into a soluble expression vector and expressed in Escherichia coli for characterization against purified microcystin-LR by competition enzyme-li
American Society for Microbiology.
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9. Colorimetric Immuno-Protein Phosphatase Inhibition Assay for Specific Detection of Microcystins and Nodularins of Cyanobacteria
A novel immunoassay was developed for specific detection of cyanobacterial cyclic peptide hepatotoxins which inhibit protein phosphatases. Immunoassay methods currently used for microcystin and nodularin detection and analysis do not provide information on the toxicity of microcystin and/or nodularin variants. Furthermore, protein phosphatase inhibition-base
American Society for Microbiology.
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10. Toxicity and toxins of natural blooms and isolated strains of Microcystis spp. (Cyanobacteria) and improved procedure for purification of cultures.
All samples of cyanobacterial blooms collected from 1986 to 1989 from Lake Kasumigaura, Ibaraki Prefecture, Japan, were hepatotoxic. The 50% lethal doses (LD50s) of the blooms to mice ranged from 76 to 556 mg/kg of body weight. Sixty-eight Microcystis cell clones (67 Microcystis aeruginosa and 1 M. viridis) were isolated from the blooms. Twenty-three strains
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11. Isolation and characterization of a variety of microcystins from seven strains of the cyanobacterial genus Anabaena.
Hepatotoxins (microcystins) from seven freshwater Anabaena strains originating from three different Finnish lakes and one lake in Norway were isolated by high-performance liquid chromatography and characterized by amino acid analysis and fast atom bombardment mass spectrometry. All strains produced three to seven different microcystins. A total of 17 differe
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12. Variation of microcystins, cyanobacterial hepatotoxins, in Anabaena spp. as a function of growth stimuli.
Cyanobacterial hepatotoxins, microcystins, are specific inhibitors of serine/threonine protein phosphatases and potent tumor promoters. They have caused several poisonings of animals and also pose a health hazard for humans through the use of water for drinking and recreation. Different strains of the same cyanobacterial species may variously be nontoxic, be