Methadone
Mostrando 13-24 de 60 artigos, teses e dissertações.
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13. Extradural anesthesia with lidocaine combined with fentanyl or methadone to ovariohisterectomy in dogs
PURPOSE: To compare the cardiopulmonary effects and the quality of anesthesia of the extradural lidocaine in combination with fentanyl or morphine in bitches undergoing ovariohysterectomy. METHODS: Sixteen female dogs, were sedated with intramuscular acepromazine (0.05mg kg-1), followed by anesthetic induction with intravenous propofol (4mg kg-1), to perform
Acta Cir. Bras.. Publicado em: 2013-07
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14. Detomidina isolada e associada à morfina e à metadona para abordagem da cavidade oral em equinos: efeitos sedativos, antinociceptivos e cardiorrespiratórios / Detomidine alone or in combination with morphine and methadone to oral cavity approach in horses: sedative, antinociceptive and cardiopulmonary effects
Objetivou-se avaliar os efeitos sedativos, antinociceptivos e cardiorrespiratórios da administração da detomidina isolada e associada à morfina e metadona para abordagem da cavidade oral de equinos em posição quadrupedal. Foram avaliadas seis éguas, mestiças, adultas, com peso médio de 42842kg, que foram distribuídas em delineamento de quadrado lat
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/09/2011
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15. Repercussão da substituição da infusão venosa de fentanil por metadona enteral sobre o tempo de desmame da ventilação mecânica em pacientes graves internados em unidades de terapia intensiva de adultos / Effect of substitution of intravenous infusion of fentanyl by enteral methadone on the time of weaning from mechanical ventilation in critically ill patients in intensive care units for adults
INTRODUCTION: Patients on mechanical ventilation (MV) are often subjected to prolonged use and / or high doses of opioids, which when removed can cause withdrawal syndrome and to difficult weaning from MV. Objective: to test the hypothesis that the introduction of enteral methadone in weaning from sedation and analgesia in critically ill adult patients on MV
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 11/08/2011
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16. Osteossíntese de tibiotarso com miniplaca de titânio em Arara Canindé (Ara ararauna)
Among the surgical problems of birds, fractures are the most prevalent, and the long bones of the wings and pelvic limbs are the most frequently affected. The success of orthopedic surgery in birds is directly related to the techniques used to undo the mechanical forces of a fracture. At the veterinary teaching hospital a psitacid from the Ara ararauna (blue
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2011-08
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17. Estudo farmacocinético da metadona por via oral em cães
Esta dissertação teve como objetivo determinar parâmetros farmacocinéticos da metadona utilizada por via oral em diferentes formas farmacêuticas. A metadona foi administrada i.v. e v.o. (líquido e comprimido) (0,5 mg/kg) em cães da raça Cocker Spaniel Inglês. Foi também utilizada metadona comprimido (0,5 mg/kg) associada a cetoconazol (10 mg/kg, du
Publicado em: 2011
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18. Comparison of intramuscular or epidural methadone analgesic effects for cats submitted to ovariohysterectomy / Comparação do efeito analgésico da metadona via intramuscular ou epidural em gatas submetidas a ovariossalpingohisterectomia
This study compared the analgesic, sedative and neuroendocrine effects of the epidural (EP) and intramuscular (IM) methadone in cats submitted to ovariohisterectomy. Cats were randomly assigned to three groups of 08 animals each and received EP or IM methadone (0.2mg.kg-1 diluted with saline to 0.2ml.kg-1, G1 and G2, respectively) or a saline placebo (G3). P
Publicado em: 2008
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19. IN VITRO AND IN VIVO STUDY OF SUBARACHNOID ADMINISTRATION OF HYPERBARIC OPIOIDS IN HORSES / ESTUDO in vitro E in vivo DA ADMINISTRAÇÃO SUBARACNÓIDE DE OPIÓIDES HIPERBÁRICOS EM CAVALOS
Este trabalho apresenta a investigação da utilização de soluções hiperbáricas de opióides e glicose a 10% em um modelo experimental in vitro do espaço subaracnóide, bem como o estudo in vivo da administração de opióides hiperbáricos e glicose a 10% pela via subaracnóide em cavalos. A primeira fase in vitro, constou da utilização de um modelo
Publicado em: 2006
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20. Nevirapine Significantly Reduces the Levels of Racemic Methadone and (R)-Methadone in Human Immunodeficiency Virus-Infected Patients
Methadone is metabolized by various isoforms of the cytochrome P450 family, which can be induced by many drugs, including nevirapine. The objective of the present study was to determine the effects of coadministration of nevirapine and methadone on the dose-adjusted areas under the concentration-time curves (AUCs) of racemic and (R)-methadone. Twenty-five hu
American Society for Microbiology.
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21. Nonconventional opioid binding sites mediate growth inhibitory effects of methadone on human lung cancer cells.
Methadone was found to significantly inhibit the in vitro and in vivo growth of human lung cancer cells. The in vitro growth inhibition (occurring at 1-100 nM methadone) was associated with changes in cell morphology and viability detectable within 1 hr and was irreversible after a 24-hr exposure to the drug. These effects of methadone could be reversed in t
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22. Methadone maintenance in the treatment of opioid dependence. A current perspective.
We describe the historical underpinnings of negative attitudes towards methadone and how these affect medical decisions. Current developments have increased the understanding of the origins of opioid addiction, such as how receptor system dysfunction may affect the ability to remain abstinent once out of treatment. Specialized topics include the pregnant add
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23. Fatal methadone and heroin overdoses: time trends in England and Wales.
STUDY OBJECTIVE: Although the total number of self poisonings in England and Wales has dropped by 32%, the number involving methadone and/or heroin rose by 900% in 1974-92. Because of concern about the role of methadone in this increase, the part played by methadone and heroin in poisoning deaths in England and Wales in 1974-92 was investigated. DESIGN: A pr
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24. Methadone: Antimicrobial Activity and Interaction with Antibiotics
We studied the effect of methadone, alone and in combination with antimicrobial agents, on two strains each of Staphylococcus aureus, Pseudomonas aeruginosa, and Serratia marcescens isolated from blood streams of parenteral drug abusers with bacterial endocarditis. Methadone has its own antibacterial effect, although at supraphysiological concentrations, and