Metabolic Pathways
Mostrando 13-24 de 837 artigos, teses e dissertações.
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13. METABOLÔMICA MICROBIANA: INOVAÇÕES E APLICAÇÕES
Over the past few years, metabolomics has been employed in a broad range of applications in different research fields. Microbial metabolomics has been applied in several microbiological areas, such as identification of microorganisms, cell mutations, functional gene approach, identification of unique metabolic pathways and microbial engineering, leading to a
Quím. Nova. Publicado em: 18/07/2019
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14. Structural equation modeling of associations between night work and glycemic levels
ABSTRACT Objective Different pathways may lead from night work to metabolic diseases, including type 2 diabetes. This study aimed to explore the direct and indirect pathways from night work to glycemic levels, considering the role of physical activity, waist circumference and snacking using data from ELSA-Brasil. Materials and methods A structural equation
Arch. Endocrinol. Metab.. Publicado em: 27/06/2019
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15. Hormonal Biomarkers for Evaluating the Impact of Fetal Growth Restriction on the Development of Chronic Adult Disease
Resumo A hipótese das origens fetais de doenças em adultos propõe que distúrbios crônicos metabólicos, incluindo doenças cardiovasculares, diabetes e hipertensão, se originam na plasticidade do desenvolvimento devido a insultos intrauterinos. Estes processos envolvem uma resposta adaptativa do feto amudanças nos sinais ambientais que podem promover
Rev. Bras. Ginecol. Obstet.. Publicado em: 19/06/2019
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16. Kidney Disease in Diabetes Mellitus: Cross-Linking between Hyperglycemia, Redox Imbalance and Inflammation
Resumo A hiperglicemia crônica é o ponto-chave das complicações macro e microvasculares associadas ao diabetes mellitus. O excesso de glicose é responsável por induzir desequilíbrio redox e inflamação sistêmica e intra-renal, desempenhando um papel crítico na patogênese da doença renal do diabetes, configurada atualmente como a principal causa d
Arq. Bras. Cardiol.. Publicado em: 06/06/2019
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17. Mechanisms by Which Metabolic Reprogramming in GSD1 Liver Generates a Favorable Tumorigenic Environment
Abstract Glycogen storage disease type 1 (GSD1) is an inherited disorder caused by impaired glucose 6-phosphatase activity. This impairment translates into the inhibition of endogenous glucose production and the subsequent accumulation of cellular glucose 6-phosphate. Excess glucose 6-phosphate enhances glycolysis, increases the production of fatty acids, ur
J. inborn errors metab. screen.. Publicado em: 30/05/2019
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18. Role of Adiponectin in prostate cancer
ABSTRACT Obesity is defined as a chronic and excessive growth of adipose tissue. It has been associated with a high risk for development and progression of obesity-associated malignancies, while adipokines may mediate this association. Adiponectin is an adipose tissue-derived adipokines, with significant anti-diabetic, anti-inflammatory, anti-atherosclerotic
Int. braz j urol.. Publicado em: 27/05/2019
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19. The Link Between Hyperhomocysteinemia and Hypomethylation: Implications for Cardiovascular Disease
Abstract Increased levels of homocysteine have been established as a risk factor for cardiovascular disease (CVD) by mechanisms still incompletely defined. S-Adenosylhomocysteine (SAH) is the metabolic precursor of homocysteine that accumulates in the setting of hyperhomocysteinemia and is a negative regulator of most cell methyltransferases. Several observa
J. inborn errors metab. screen.. Publicado em: 16/05/2019
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20. Protein-protein interactions of the nicotinamide/nicotinate mononucleotide adenylyltransferase of Leishmania braziliensis
BACKGROUND Nicotinamide adenine dinucleotide (NAD) plays a central role in energy metabolism and integrates cellular metabolism with signalling and gene expression. NAD biosynthesis depends on the enzyme nicotinamide/nicotinate mononucleotide adenylyltransferase (NMNAT; EC: 2.7.7.1/18), in which converge the de novo and salvage pathways. OBJECTIVE The pu
Mem. Inst. Oswaldo Cruz. Publicado em: 21/03/2019
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21. Laboratory Diagnosis of Peroxisomal Disorders in the -Omics Era and the Continued Importance of Biomarkers and Biochemical Studies
Abstract The clinical as well as biochemical and genetic spectrum of peroxisomal diseases has markedly increased over the last few years, thanks to the revolutionary advances in the field of genome analysis and several -omics technologies. This has led to the recognition of novel disease phenotypes linked to mutations in previously identified peroxisomal gen
J. inborn errors metab. screen.. Publicado em: 28/02/2019
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22. Effect of salicylic acid and silver nitrate on rutin production by Hyptis marrubioides cultured in vitro
RESUMO: Hyptis marrubioides (Lamiaceae) é uma planta medicinal nativa do Cerrado brasileiro. Técnicas de propagação in vitro fazem uso de elicitores para alterar as vias metabólicas, afetando a produção de moléculas qualitativa e quantitativamente. Este trabalho teve como objetivo avaliar como os elicitores abióticos ácido salicílico (SA) e nitrat
Cienc. Rural. Publicado em: 18/02/2019
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23. Oxidative stress and fish immune system: phagocytosis and leukocyte respiratory burst activity
Abstract Molecular oxygen is a necessary compound for all aerobic organisms, although oxygen is a potent oxidant, which can cause oxidative stress (OS). OS occurs when there is an imbalance between the production of oxidant and antioxidants components, are result of normal cell metabolism, and many of these compounds play a fundamental role in several metabo
An. Acad. Bras. Ciênc.. Publicado em: 18/10/2018
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24. Atrazine and nicosulfuron affect the reproductive fitness of the predator Podisus nigrispinus (Hemiptera: Pentatomidae)
Abstract Herbicides can impact non-target metabolic pathways in natural enemies and lead to the reduction of these populations in the field. Behavioral characteristics, morphology and histology of reproductive structures and reproduction of females of Podisus nigrispinus (Dallas) (Hemiptera: Pentatomidae) were evaluated under the effect of the herbicides atr
An. Acad. Bras. Ciênc.. Publicado em: 03/09/2018