Metabolic Network Analysis
Mostrando 1-12 de 60 artigos, teses e dissertações.
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1. Visual FTBL Generator: Visual Generation Tool for 13C-FLUX File
Abstract 13C metabolic flux analysis (13C-MFA) has achieved increasing significance in quantitative metabolic system analysis in recent years. In 13C metabolic flux analysis, 13C-FLUX software is a major analytical tool. The software’s input script is primarily expressed in textual form without visual presentation of the structure of the entire metabolic
Braz. arch. biol. technol.. Publicado em: 25/11/2019
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2. Protein-protein interactions of the nicotinamide/nicotinate mononucleotide adenylyltransferase of Leishmania braziliensis
BACKGROUND Nicotinamide adenine dinucleotide (NAD) plays a central role in energy metabolism and integrates cellular metabolism with signalling and gene expression. NAD biosynthesis depends on the enzyme nicotinamide/nicotinate mononucleotide adenylyltransferase (NMNAT; EC: 2.7.7.1/18), in which converge the de novo and salvage pathways. OBJECTIVE The pu
Mem. Inst. Oswaldo Cruz. Publicado em: 21/03/2019
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3. Liver proteome of mice with different genetic susceptibilities to the effects of fluoride
ABSTRACT A/J and 129P3/J mice strains have been widely studied over the last few years because they respond quite differently to fluoride (F) exposure. 129P3/J mice are remarkably resistant to the development of dental fluorosis, despite excreting less F in urine and having higher circulating F levels. These two strains also present different characteristics
J. Appl. Oral Sci.. Publicado em: 2016-06
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4. Comparisons Between Different Methods in Measuring Enzyme Similarity for Metabolic Network Alignment
Metabolic network alignments enable comparison of the similarities and differences between pathways in two metabolic networks and help to uncover the conserved sub-blocks therein. Such analysis is important in the understanding of metabolic networks and species evolution. The fundamental parts of metabolic network alignment algorithms all involve comparisons
Braz. arch. biol. technol.. Publicado em: 22/03/2016
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5. Prevalence of the rs1801282 single nucleotide polymorphism of the PPARG gene in patients with metabolic syndrome
Objective This study aimed to get the genotypic and allelic frequencies of rs1801282 in 179 volunteer donors and 154 patients with Metabolic syndrome (MetS) in Brasilia, Brazil and also examine the association with anthropometric, biochemical and hemodynamic variables in the latter group. MetS comprises a group of diseases resulting from insulin resistance,
Arch. Endocrinol. Metab.. Publicado em: 2015-08
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6. Cardiovascular risk factors in outpatients with bipolar disorder: a report from the Brazilian Research Network in Bipolar Disorder
Objective: Bipolar disorder (BD) is associated with significant morbidity and mortality due to comorbid general medical conditions, particularly cardiovascular disease. This study is the first report of the Brazilian Research Network in Bipolar Disorder (BRN-BD) that aims to evaluate the prevalence and clinical correlates of cardiovascular risk factors amon
Rev. Bras. Psiquiatr.. Publicado em: 2013-06
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7. Impaired expression of NER gene network in sporadic solid tumors
Nucleotide repair genes are not generally altered in sporadic solid tumors. However, point mutations are found scattered throughout the genome of cancer cells indicating that the repair pathways are dysfunctional. To address this point, in this work we focus on the expression pathways rather than in the DNA structure of repair genes related to either genome
Publicado em: 2010
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8. Metabolic Network Comparison of Bacteria in the Context of Symbiosis / Análise Comparativa de Redes Metabólicas de Bactérias no Contexto da Simbiose
Simbiose é a associação permanente entre dois ou mais organismos de espécies distintas, pelo menos durante uma parte do ciclo de vida. Existe uma grande diversidade de casos de simbiose, os quais são frequentemente classificados de acordo com os benefícios ou deficits no valor adaptativo do hospedeiro, i.e., mutualismo, comensalismo ou parasitismo. Out
Publicado em: 2010
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9. Espectroscopia por ressonância magnética de prótons em epilepsia mioclônica juvenil sugere o comprometimento de uma rede neuronal específica
OBJECTIVES: The neuroanatomical basis and the neurochemical abnormalities that underlay juvenile myoclonic epilepsy (JME) are not fully defined. While the thalamus plays a central role in synchronization of widespread regions of the cerebral cortex during a seizure, emerging evidence suggests that all cortical neurons may not be homogeneously involved. The p
Journal of Epilepsy and Clinical Neurophysiology. Publicado em: 2008-09
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10. Análise de nutrientes utilizando redes metabólicas
In this work we present an introduction to metabolic networks of organisms, its main biological concepts, different data structures that can be used to model these networks and a formal definition of three of the main problems related to nutrient analysis. Finally, this work presents a method based on the topology of the network to enumerate all the precurso
Publicado em: 2008
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11. Processamento de perfis metabólicos / Metabolic profiles processing
During the past 30-years, Biochemical System Theory (BST) has been provided a concrete foundation for the study of the dynamic biological systems, e.g. S-systems models for reverse engineering of metabolic networks (Savageau, 1969; Savageau, 1970; Voit, 2000). One of the remarkable characteristics of these models is its parameters not only quantify the inter
Publicado em: 2007
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12. Avaliação do desenvolvimento de girassol por meio de analise de proteinas e metaloproteinas / Evaluation of sunflower development based on protein metalloprotein analysis
This work describes an evaluation of sunflower (Helianthus annuus L.) growth when it is submitted to seven treatments, and their interrelation with proteins and metalloproteins analyses. Metal ion solutions (Cd, Cu, Pb and Zn) were added to the substrate in four treatments. In another two, used as controls, the plants were irrigated only with deionized water
Publicado em: 2006