Mannose Binding Lectin
Mostrando 13-24 de 140 artigos, teses e dissertações.
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13. Estudo da influência dos polimorfismos da lectina ligadora da manose e hábito tabagista sobre os índices de atividade, cronicidade e dano de pacientes com lúpus eritematoso sistêmico
O lúpus eritematoso sistêmico (LES) é uma doença auto-imune caracterizada pela produção de múltiplos auto-anticorpos, com componentes celulares nucleares como principal alvo. De etiologia desconhecida, envolve fatores genéticos, imunológicos, hormonais e ambientais. A deficiência na lectina ligadora da manose (MBL), um dos componentes do sistema de
Publicado em: 2011
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14. Concanavalina-A aumenta a produção de TNF-a, a atividade de receptores de manose e a capacidade de destruir Candida por macrófagos peritoneais
Recognition of Candida albicans by Toll-like receptors and lectin receptors on the phagocytic cells activates intracellular signaling pathways that trigger production of proinflammatory cytokines that are critical for host defence. Th1-response provide control of fungal infectivity by increasing the expression of receptors that acts as sensors for infection
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 22/02/2010
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15. High levels of serum mannose-binding lectin are associated with the severity of clinical signs of leptospirosis
The clinical heterogeneity observed in leptospirosis may be associated with host factors or bacteria virulence. Human serum mannose-binding lectin (MBL) recognizes many pathogens, and low levels of this lectin are associated with susceptibility to infection. MBL is also implicated in the modulation of the inflammatory process. We determined the levels of ser
Brazilian Journal of Medical and Biological Research. Publicado em: 2009-04
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16. Contagem de células somáticas e bacteriana total, sequenciamento dos exons 1 e 2 do gene Mannose-binding Lectin (MBL) em caprinos de rebanhos pernambucanos
Mastitis is the inflammatory process of mammary gland which has infectious origin or not. It is characterized by physic-chemical and bacteriological alterations of milk and unrepairable lesions on the mammary tissue. In goats used for milk production, mastitis is a serious problem, as much for increasing production costs as for public health risks. In this w
Publicado em: 2009
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17. HistoquÃmica com lectinas de sementes de Cratylia mollis analisando tecidos prostÃticos humanos
Prostate cancer is a malignant tumour of major incidence in elderly men in the developed countries and the second major cause of death for cancer. Lectins are proteins or glycoproteins, which recognize specifically and reversibly free or conjugated carbohydrates. They have been used in histochemistry to evaluate changes in the composition and expression of c
Publicado em: 2009
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18. Polimorfismos genÃticos da mannose binding lectin em adolescentes com diabetes melito tipo 1
Type 1 diabetes is an autoimmune disease in which progressive destruction of pancreatic beta cells results in persistent hyperglycemia. Despite all the progress, the etiopathogenic mechanisms of this disease, is still not very well understood, which difficult the discovery of effective methods of prevention and cure. With the development of studies, several
Publicado em: 2009
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19. Estudo dos polimorfismos da lectina ligadora da manose em pacientes com lúpus eritematoso sistêmico
O Lúpus Eritematoso Sistêmico (LES) é uma doença inflamatória sistêmica autoimune caracterizada pela produção e deposição de imunocomplexos. Sua etiologia é pouco conhecida, mas há evidências da participação de fatores genéticos. Vários genes responsáveis pela síntese de proteínas do Sistema Complemento (SC) têm sido relacionados com LES
Publicado em: 2009
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20. Characterization of polymorphisms in the mannose-binding lectin gene promoter among human immunodeficiency virus 1 infected subjects
The present study investigated the prevalence of mutations in the -550 (H/L) and -221 (X/Y) mannose-binding lectin (MBL) gene promoter regions and their impact on infection by human immunodeficiency virus 1 (HIV-1) in a population of 128 HIV-1 seropositive and 97 seronegative patients. The allele identification was performed through the sequence-specific pri
Memórias do Instituto Oswaldo Cruz. Publicado em: 2008-11
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21. AvaliaÃÃo do polimorfismo da lectina ligadora de manose (MBL-2) na patogÃnese do lÃquen plano oral
Background: Current evidence suggests that the etiopathogenesis of oral lichen planus (OLP) is a T cells mediated process possibly associated with tumor necrosis factor alpha. Mannose-binding lectin is a multimer protein responsible for the activation of the complement system. It has been suggested that low levels of MBL, possibly associated with its polymor
Publicado em: 2008
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22. Immobilization of proteins onto polysaccharide surfaces / Imobilização de proteínas sobre superfícies de polissacarídeos
This thesis presents the study on thin film formation and characterization of xyloglucans extracted from two different sources, Hymenaea courbaril (HXG) and Tamarindus indica (TXG) onto Si/SiO2 wafers or amino-terminated wafers, as well as the application of these films as substrates for the immobilization of the lectin concanavalin A (Con A) by means of ell
Publicado em: 2008
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23. Perfil do polimorfismo GÃnico da β-defensina-1 e da MBL2 em pacientes com diagnÃstico de onicomicose causadas por Candida spp
The human β-defensin-1 (hBD1) and mannose-binding lectin (MBL) are important components of the innate immune system. β-defensin-1 are peptides that act as natural and antibiotics contributes as first line of body defense. MBL is a protein that binds on the surface of microorganism and enable the factivation of complement system. Single nucleotide p
Publicado em: 2008
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24. Polimorfismo no gene da MBL-2 em mulheres infectadas por Chlamydia trachomatis, cofator do cÃncer cervical
A Chamydia trachomatis (C. trachomatis) Ã uma bactÃria intracelular obrigatÃria, sexualmente transmitida, que causa doenÃa inflamatÃria pÃlvica, gravidez ectÃpica e infertilidade. O papilomavÃrus humano (HPV) e a C. trachomatis sÃo responsÃveis por infecÃÃes sexualmente transmissÃveis (ISTs) tipo-especÃficas, que infectam a pele, mucosas e o tr
Publicado em: 2008