Macrophages Pathology
Mostrando 1-12 de 109 artigos, teses e dissertações.
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1. A função da IL-10 na paracoccidioidomise pulmonar murina. / The role of IL-10 in murine pulmonary paracoccidioidomycosis.
Cellular immunity is the main defense mechanism of hosts infected by the Paracoccidioide brasiliensis (Pb), a dimorphic fungus that causes the most important systemic mycosis in Latin America. IFN-g activated macrophages participate in this activity that is antagonized by IL-10 an anti-inflammatory cytokine. Both, in the human pathology a
Publicado em: 2010
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2. Aspectos clínico-patológicos da paratuberculose em rebanho bovino leiteiro no município de Rio Claro, RJ. / Clinic-pathological aspects of paratuberculosis in dairy cattle in Rio Claro county, Rio de Janeiro State.
The epidemic and clinic-pathological aspects of paratuberculois in a dairy cattle herd in the Rio Claro county, southern Rio de Janeiro region, are described. In the years 2006-2009, eight adult cows presented chronic-intermittent diarrhea, chronic weight loss and normal appetite. At necropsy, the subserosal lymphatics were proeminent and dilated, mesenteric
Publicado em: 2010
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3. POLIOENCEFALOMALACIA EM RUMINANTES / POLIOENCEPHALOMALACIA IN RUMINANTS
In the first portion of this thesis, epidemiology, clinical signs and distribution of lesions in the brain of thirty one cases of polioencephalomalacia (PEM) in cattle from the Southern (13 cases) and Midwestern (18 cases) Brazil were studied. Morbidity (0.04%-6.66 %), mortality (0.04%-6.66 %), and lethality (50%-100%) rates were similar in both regions stud
Publicado em: 2010
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4. Estudo clinicopatologico e imunoistoquimico de prurigo actinico de labio / Clinicopathological and imunohistochemical study af actinic prurigo of lip
Actinic prurigo (AP) is a specific familial photodermatosis that affects mainly mestizos, who live in many parts of North, Central and South America. AP can be clinically evident at any age, but it starts in infancy, between 6 and 8 years of age. It is more frequent in women. AP affects mainly persons living in regions above one thousand meters sea level. Th
Publicado em: 2009
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5. Participação do fator inibidor da migração de macrófagos (MIF) no processo inflamatório pulmonar induzido por sílica em camundongos / Involvement of inhibitory factor macrophage migration (MIF) in pulmonary inflammation induced by silica in mice
A silicose é a pneumoconiose de maior prevalência no Brasil e resulta da exposição às partículas de sílica cristalina, sendo caracterizada por infiltrado inflamatório, deposição de colágeno e formação de granulomas, em um contexto dependente de uma gama de mediadores. O fator inibidor da migração de macrófagos (MIF) é uma citocina pró-infla
Publicado em: 2009
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6. Papel da 5-Lipoxigenase no controle da carga parasitária e no estresse oxidaltivo de eritrócitos durante a fase aguda da infecção experimental com Trypanosoma cruzi
Recently, it was demonstrated that nitric oxide (NO) produced during Trypanosoma cruzi infection participates of erythrocyte oxidative stress, but is not necessary for the development of anemia in the acute phase of infection in mice. In this work it was investigated the effect of inhibition of leukotrienes (LTs) by pharmacological or genetic blocking of the
Publicado em: 2007
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7. Multiple sclerosis: high resolution magnetic resonance spectroscopy and correlation with inflammatory course / Esclerose multipla : espectroscopia de protons de resolução do liquor e correlação com atividade inflamatoria
We studied cerebrospinal fluid (CSF) of 24 patients with multiple sclerosis (MS) and 11 control subjects by high resolution proton MR spectroscopy. The application of 1 H magnetic resonance spectroscopy in cerebrospinal fluid (CSF) analysis may detect metabolites in normal and pathological conditions. The purpose of this work was to evaluate what biochemical
Publicado em: 2007
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8. Avaliação da eficacia de diferentes compostos nos modelos in vitro e in vivo da leishmaniose sob diferentes condições de oxigenio / Efficacy of different compounds in leishmaniasis in vitro and in vivo models under different oxygen tensions
L. amazonensis, a species transmitted mainly in the Amazon region, which is associated with localized cutaneous lesions and chemotherapy remains the mainstay for the control of leishmaniasis, as effective vaccines have yet to be developed. In this context, there is an intense search for potential new synthetic compounds and natural products for the treatment
Publicado em: 2007
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9. Estudo da micobacteriose pulmonar em pacientes autopsiados com e sem AIDS : avaliação histopatologica, imunohistoquimica e caracterização das especies de micobacterias por PCR
Introduction: Micobacteriosis (MB) is one of the main causes of deaths around the world and its incidence has been increased significantly with the emergence of the AIDS. Objectives: Our aims were to compare the pattern of the inflammatory response in the pulmonary MBs (PMB) between two groups (Group I: PMB; Group II: PMB/AIDS), and to identify the mycobacte
Publicado em: 2006
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10. Salpingitis due to Entamoeba histolytica
We describe the pathology of a unique case of Fallopian tube amebiasis, associated with hydrosalpinx, in a 21-year-old woman. She complained of lower abdominal pain, had a foul-smelling green vaginal discharge and fever during one week. There was a discrete increase in body temperature and a painful abdominal palpation at the lower right side, with signs of
Brazilian Journal of Infectious Diseases. Publicado em: 2002-04
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11. The extracellular matrix in multiple sclerosis: an update
Extracellular matrix (ECM) molecules play important roles in the pathobiology of the major human central nervous system (CNS) inflammatory/demyelinating disease multiple sclerosis (MS). This mini-review highlights some recent work on CNS endothelial cell interactions with vascular basement membrane ECM as part of the cellular immune response, and roles for w
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-05
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12. Critical Role for Interleukin-1β (IL-1β) during Chlamydia muridarum Genital Infection and Bacterial Replication-Independent Secretion of IL-1β in Mouse Macrophages▿
Recent findings have implicated interleukin-1β (IL-1β) as an important mediator of the inflammatory response in the female genital tract during chlamydial infection. But how IL-1β is produced and its specific role in infection and pathology are unclear. Therefore, our goal was to determine the functional consequences and cellular sources of IL-1β express
American Society for Microbiology (ASM).