Lung Growth Development
Mostrando 1-12 de 146 artigos, teses e dissertações.
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1. Cytotoxic activity of Androctonus australis hector venom and its toxic fractions on human lung cancer cell line
Abstract Background: Several studies have showed that animal venoms are a source of bioactive compounds that may inhibit the growth of cancer cells, which makes them useful agents for therapeutic applications. Recently, it was established that venom toxins from scorpions induced cytotoxic, antiproliferative and apoptogenic effects on cancer cells. Therefore
J. Venom. Anim. Toxins incl. Trop. Dis. Publicado em: 01/12/2016
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2. Downregulation of survivin by siRNA inhibits invasion and promotes apoptosis in neuroblastoma SH-SY5Y cells
Neuroblastoma is a solid tumor that occurs mainly in children. Malignant neuroblastomas have a poor prognosis because conventional chemotherapeutic agents are not very effective. Survivin, a member of the inhibitor of the apoptosis protein family, plays a significant role in cell division, inhibition of apoptosis, and promotion of cell proliferation and inva
Braz J Med Biol Res. Publicado em: 23/05/2014
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3. VEGF receptor expression decreases during lung development in congenital diaphragmatic hernia induced by nitrofen
Changes in vascular endothelial growth factor (VEGF) in pulmonary vessels have been described in congenital diaphragmatic hernia (CDH) and may contribute to the development of pulmonary hypoplasia and hypertension; however, how the expression of VEGF receptors changes during fetal lung development in CDH is not understood. The aim of this study was to compar
Braz J Med Biol Res. Publicado em: 2014-02
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4. Growth following solid organ transplantation in childhood
One of the ultimate goals of successful solid organ transplantation in pediatric recipients is attaining an optimal final adult height. This manuscript will discuss growth following transplantation in pediatric recipients of kidney, liver, heart, lung or small bowel transplants. Remarkably similar factors impact growth in all of these recipients. Age is a pr
Clinics. Publicado em: 2014-01
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5. Long-term outcomes of children after solid organ transplantation
Solid organ transplantation has transformed the lives of many children and adults by providing treatment for patients with organ failure who would have otherwise succumbed to their disease. The first successful transplant in 1954 was a kidney transplant between identical twins, which circumvented the problem of rejection from MHC incompatibility. Further pro
Clinics. Publicado em: 2014-01
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6. Myeloid-derived suppressor cells and associated events in urethane-induced lung cancer
OBJECTIVES: Myeloid-derived suppressor cells contribute to the immunosuppressive microenvironment during tumor development and limit the efficacy of cancer immunotherapy. Identifying myeloid-derived suppressor cells and associated factors is the first step in creating strategies to reverse the suppressive effects of these cells on the immune system. METHO
Clinics. Publicado em: 2013-06
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7. Estudo da atividade citotóxica do poliacetileno 5-octa-2, 4, 6-triinil-furan-2(5H)-ona / Study of the cytotoxic activity of polyacetylene 5-octa-2,4,6-triinil-furan-2 (5H)-one
Skin cancers are the most common types of cancer in Brazil, and correspond to around 25% of all malignant tumors recorded. Of these, melanoma represents at least 5% and is characterized by its high metastatic power. The development of anticancer agents from natural products is considered critical to pharmacology, and interest in the development of more effec
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 26/06/2012
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8. Epidermal growth factor receptor and KRAS mutations in Brazilian lung cancer patients
OBJECTIVE: Epidermal growth factor receptor is involved in the pathogenesis of non-small cell lung cancer and has recently emerged as an important target for molecular therapeutics. The KRAS oncogene also plays an important role in the development of lung cancer. The aim of this study was to evaluate the frequency of epidermal growth factor receptor and KRAS
Clinics. Publicado em: 2012
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9. Estudo do volume pulmonar fetal na predição dos resultados perinatais de fetos com derrame pleural \"isolado / Three-dimensional ultrasonographic assessment of fetal lung volume as a prognostic factor in isolated pleural effusion
OBJETIVO: O objetivo deste estudo foi predizer o prognóstico perinatal em fetos com derrame pleural isolado por meio da medida do volume pulmonar estimado pela ultrassonografia tridimensional. MÉTODO: Estudo retrospectivo, entre julho de 2005 e julho de 2010, com 19 fetos com derrame pleural isolado (ausência de causas infecciosas, imunes, anomalias cromo
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 14/12/2011
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10. In vitro modulation of Bcl-2 levels in small cell lung cancer cells: effects on cell viability
Small cell lung cancer (SCLC) is an aggressive disease, representing 15% of all cases of lung cancer, has high metastatic potential and low prognosis that urgently demands the development of novel therapeutic approaches. One of the proposed approaches has been the down-regulation of BCL2, with poorly clarified and controversial therapeutic value regarding SC
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-10
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11. Increased expression of tissue factor and protease-activated receptor-1 does not correlate with thrombosis in human lung adenocarcinoma
A correlation between cancer and hypercoagulability has been described for more than a century. Patients with cancer are at increased risk for thrombotic complications and the clotting initiator protein, tissue factor (TF), is possibly involved in this process. Moreover, TF may promote angiogenesis and tumor growth. In addition to TF, thrombin seems to play
Brazilian Journal of Medical and Biological Research. Publicado em: 2010-04
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12. Efeito da dieta à base de Cogumelo do Sol (Agaricus blazei, Murrill) no parênquima pulmonar de ratos submetidos a estímulo carcinogênico pela nitrosamina 4-metilnitrosamina-1-3piridil-1 butanona (NNK) / Effect of diet of sun mushroom (Agaricus blazei Murrill) in the lung parenchyma of rats subjected to stimulation with the carcinogen nitrosamine-4-1-metilnitrosamine 3piridil-1butanone (NNK)
The mushrooms have been used for many years as food for its nutritional value and/or as a therapeutic agent. One of the most studied fungus is currently the Agaricus blazei Murrill, popularly Known as Cogumelo do Sol, for its beneficial credited in the prevention of cancer. This study examined the effects of ingestion of A. blazei in the lung parenchyma of w
Publicado em: 2010