Liquid Formulations
Mostrando 1-12 de 166 artigos, teses e dissertações.
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1. Graphite-Polyurethane Composite Electrode Modified with Molecularly Imprinted Polymer for Determination of Diclofenac
A molecularly imprinted polymer (MIP) was prepared using the anti-inflammatory diclofenac (DCF) as a template. A non-imprinted polymer (NIP) was also prepared as a control. These MIP and NIP were characterized by scanning electron microscopy (SEM), transmission electron microscopy (TEM) and Brunauer-Emmett-Teller (BET), revealing a higher porosity in the fir
Journal of the Brazilian Chemical Society. Publicado em: 2022
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2. Stability Indicating Method for Determination of Benznidazole and Its Degradation Products in Active Pharmaceutical Ingredient
Currently, treatment of Chagas disease is restricted to the use of benznidazole and nifurtimox; however, nifurtimox was temporarily suspended in some countries. Based on the limitations in pharmacological treatments, it is essential to guarantee the quality of benznidazole. Therefore, this work aimed to identify the degradation products of benznidazole and t
J. Braz. Chem. Soc.. Publicado em: 2020-06
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3. Preformulation of a liquid dosage formulation of captopril for pediatric use: drug-excipient compatibility and stability studies
Currently, medications used in children are typically modified from pharmaceutical dosage forms designed for adults. Captopril is widely adapted to liquid formulations for use in hospitals. Its stability in the aqueous medium is reduced since it undergoes oxidation producing captopril disulfide (its main metabolite). The aim of this formulation study was to
Braz. J. Pharm. Sci.. Publicado em: 20/12/2019
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4. Square-Wave Voltammetry Determination of Ciprofloxacin in Pharmaceutical Formulations and Milk Using a Reduced Graphene Oxide Sensor
In this paper, a simple, sensitive and precise electroanalytical method was developed using a chemically-reduced graphene-oxide (CRGO)-modified glassy carbon electrode and square wave voltammetry (SWV) for determination of ciprofloxacin in pharmaceutical formulations (tablets) and milk samples. Advantages of this sensor include a potential displacement of 10
J. Braz. Chem. Soc.. Publicado em: 16/09/2019
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5. Geopropolis gel for the adjuvant treatment of candidiasis – formulation and in vitro release assay
ABSTRACT The geopropolis produced by the stingless bee Melipona subnitida (popularly called "jandaíra" in Brazil) is a mixture of resin, wax, and mud. This study analyzed the antifungal activity of the geopropolis extract from Candida spp., developed a gel formulation with this extract and analyzed the delivery of bioactives (kinetics release) in the formul
Rev. bras. farmacogn.. Publicado em: 26/08/2019
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6. Cytotoxicity, Biocompatibility and Biomineralization of a New Ready-for-Use Bioceramic Repair Material
Resumo Novas formulações de agregado de trióxido mineral (MTA) são constantemente introduzidas no mercado, geralmente em forma de pó e líquido. O Biocerâmico (Bio-C) Reparador (Repair) é um material pronto para uso sugerido como substituto do MTA, mas suas propriedades precisam ser estudadas. Este estudo avaliou a citotoxicidade, biocompatibilidade e
Braz. Dent. J.. Publicado em: 22/07/2019
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7. Mineral content, phenolic compounds and bioactive amines of cheese bread enriched with cowpea
ABSTRACT Cheese bread presents great acceptance and market expansion. Due to the lack of standardization in its manufacturing, various ingredients can be added. It was aimed to determine the content of minerals, bioactive compounds and antioxidant activity in cheese bread enriched with biofortified cowpea. Two formulations were prepared, standard cheese brea
Food Sci. Technol. Publicado em: 13/06/2019
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8. Development and validation of a quantification method for α-humulene and trans-caryophyllene in Cordia verbenacea by high performance liquid chromatography
ABSTRACT Acheflan® herbal medicine is the first medicine developed and produced in Brazil using Cordia verbenacea DC., Boraginaceae, essential oil as a constituent. C. verbenacea has anti-inflammatory properties, which have been directly related to α-humulene and trans-caryophyllene. Currently, the quantification of α-humulene and trans-caryophyllene in C
Rev. bras. farmacogn.. Publicado em: 27/05/2019
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9. Produção de agregado sintético de argila com reaproveitamento de resíduo de vidro
RESUMO É objetivo da construção civil, reduzir o peso das estruturas e consequentemente os custos com as fundações. A substituição de britas por agregados leves é a alternativa mais utilizada. No entanto, sobretudo no Brasil, só existe uma única fábrica de agregados leves localizada em São Paulo, sendo oportuna a pesquisa de matériasprimas para
Matéria (Rio J.). Publicado em: 20/05/2019
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10. SIMULAÇÃO DE COMBUSTÃO DO POLIBUTADIENO LÍQUIDO HIDROXILADO, PERCLORATO DE AMÔNIO E ALUMÍNIO EM FORMULAÇÕES DE PROPELENTE SÓLIDO COMPÓSITO
The present work presents combustion simulations of hydroxyl-terminated liquid polybutadiene loaded with ammonium perchlorate and aluminum, using Chemkin software and the “Plug Flow” type reactor. These materials are widely used in solid composite propellant formulations. Through this study, the effect of parameters of axial velocity, equivalence ratio,
Quím. Nova. Publicado em: 2019-02
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11. Validated high performance liquid chromatography for simultaneous determination of stability of madecassoside and asiaticoside in film forming polymeric dispersions
ABSTRACT The objective of the work was to validate the high performance liquid chromatography for simultaneous determination of stability of madecassoside and asiaticoside in Centella asiatica (L.) Urb., Apiaceae, extract-loaded film forming polymeric dispersions. High performance liquid chromatography method was validated in five topics: linearity and range
Rev. bras. farmacogn.. Publicado em: 2018-06
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12. Development and Validation of a Rapid and Reliable RP-HPLC-PDA Method for the Quantification of Six Diterpenes in Copaifera duckei, Copaifera reticulata and Copaifera multijuga Oleoresins
Oleoresins from Copaifera species are extensively used in folk medicine in Brazil, which are employed mainly in the production of cosmetic formulations in Brazil, North America and Europe. Considering the lack of validated analytical methods for the analyses of diterpenes in Copaifera oleoresins, it was developed a validated and reliable reversed-phase high-
J. Braz. Chem. Soc.. Publicado em: 2018-04