Learning Blockers
Mostrando 1-5 de 5 artigos, teses e dissertações.
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1. Efeitos pré e pós sinápticos dos inibidores da acetilcolinesterase na neurotransmissão em musculatura lisa.
Justification: The present work considers the effects of new inhibitors of acetylcholinesterase (AChE) on the reactivity and neurotransmission in rats and mice. The new anticholinesterase compounds, ITH12118 and ITH12117, have an hybrid stucture, derived from the molecule of of the anticholinesterase Tacrine and the 1,4 dihydropyridine nimodipine, a blocker
Publicado em: 2010
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2. Os efeitos da estrutura organizacional no processo de aprendizagem organizacional
The purpose of this study is to analyze the effects of organizational structure on organizational learning processes, taking into consideration the environmental context that surround this relationship and the moderating influence of elements that facilitate or block organizational learning processes. The study, conducted at the organizational unit of analys
Publicado em: 2001
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3. Pharmacological modulation of subliminal learning in Parkinson's and Tourette's syndromes
Theories of instrumental learning aim to elucidate the mechanisms that integrate success and failure to improve future decisions. One computational solution consists of updating the value of choices in proportion to reward prediction errors, which are potentially encoded in dopamine signals. Accordingly, drugs that modulate dopamine transmission were shown t
National Academy of Sciences.
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4. Inverse Regulation of Plasticity-related Immediate Early Genes by Calcineurin in Hippocampal Neurons*S⃞
In the mammalian hippocampus, changes in the expression of immediate early genes (IEGs) is thought to contribute to long term plastic changes in neurons brought about by learning tasks and high frequency stimulation of synapses. The phosphatase calcineurin has emerged as an important negative regulator of hippocampus-dependent learning and long term pote
American Society for Biochemistry and Molecular Biology.
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5. Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin
The synaptic vesicle membrane protein synaptotagmin (tagmin) is essential for fast, calcium-dependent, neurotransmitter release and is likely to be the calcium sensor for exocytosis, because of its many calcium-dependent properties. Polyphosphoinositides are needed for exocytosis, but it has not been known why. We now provide a possible connection betwe
The National Academy of Sciences of the USA.