Keratin 17
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Hydrolysis of insoluble fish protein residue from whitemouth croaker (Micropogonias furnieri) by fungi
A significant amount of insoluble fibrous protein, in the form of feather, hair, scales, skin and others are available as co-products of agro industrial processing. These wastes are rich in keratin and collagen. This study evaluated different fungi for the hydrolysis of insoluble fish protein residues. Proteins resulting from Micropogonias furnieri wastes th
Braz. arch. biol. technol.. Publicado em: 2014-02
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2. Novas funções da proteina AIRE : 1) seu papel na resposta mediada por dectina-1 em fagocitos mononucleares humanos. 2) sua associação com a queratina 17, proteina dos filamentos intermediarios / New roles of AIRE protein : 1) AIRE role in Dection-1 mediated patway in human mononuclear phagocytes and 2) AIRE association with keratin-17, a component of intermediate filaments
A Poliendocrinopatia autoimune associada a candidíase e distrofia ectodérmica (APECED) é um síndrome caracterizado pela presença de pelo menos dois sintomas clínicos, endocrinopatia autoimune, sendo que as mais comuns são hipoparatiroidismo, doença de Addison, além de candidíase mucocutânea crônica. É também comum nos pacientes o desenvolviment
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 31/07/2009
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3. Expressão gênica diferencial das células estromais obtidas de medula óssea na presença ou ausência de célula tumoral oculta em pacientes com câncer de mama / Differential gene expression of bone marrow stromal cells from breast cancer patients in the presence or abscence of occult tumor cells
Stromal cells may influence tumor development in primary and secundary sites, however, molecular characteristics of bone marrow stromal cells from breast cancer patients are almost unknown. Our aim was to evaluate the differential gene expression of bone marrow stromal cells from breast cancer patients in the presence or abscence of occult tumor cells. Bone
Publicado em: 2006
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4. Linkage of epidermolysis bullosa simplex to keratin gene loci.
Epidermolysis bullosa simplex (EBS) is an autosomal dominant disorder characterised by intraepidermal blistering of the skin. Two families with Weber-Cockayne EBS have been analysed for linkage to keratin gene loci. In the first family, linkage was found to chromosome 17 markers flanking the keratin 14 gene (D17S74: Zmax = +2.45, theta = 0.10; COL1A1: Zmax =
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5. Differential expression of keratins 10, 17, and 19 in normal cervical epithelium, cervical intraepithelial neoplasia, and cervical carcinoma.
AIM: To examine the value of immunohistochemistry in defining a keratin profile to aid cervical histopathological diagnosis. METHODS: Immunohistochemical localisation of keratins 17, 10, and 19 was studied in 268 cervical biopsies from 216 women including normal epithelia (with and without human papilloma virus), low and high grade cervical intraepithelial n
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6. Three tightly linked genes encoding human type I keratins: conservation of sequence in the 5'-untranslated leader and 5'-upstream regions of coexpressed keratin genes.
We have isolated and subcloned three separate segments of human DNA which share strong sequence homology with a previously sequenced gene encoding a type I keratin, K14 (50 kilodaltons). Restriction endonuclease mapping has demonstrated that these three genes are tightly linked chromosomally, whereas the K14 gene appears to be separate. As judged by positive
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7. A gene for pachyonychia congenita is closely linked to the keratin gene cluster on 17q12-q21.
Pachyonychia congenita (PC) is a group of hereditary syndromes which have in common a hypertrophic dystrophy of the distal nail, and are associated with a variety of additional features, notably various dyskeratoses of skin and mucous membranes. The pathology is unknown but the array of clinical features suggests the possibility of a keratin abnormality. In
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8. Epidermolytic hyperkeratosis (bullous congenital ichthyosiform erythroderma). Genetic linkage to chromosome 12q in the region of the type II keratin gene cluster.
Epidermolytic hyperkeratosis (EHK) is an autosomal dominant genodermatosis characterized by hyperkeratosis and blistering of the skin. Histopathology demonstrates suprabasilar blister formation with aggregation of tonofilaments. In this study, we tested the hypothesis that the EHK phenotype is linked to one of the suprabasilar keratins (KRT10 or KRT1) presen
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9. Disease-activated transcription factor: allergic reactions in human skin cause nuclear translocation of STAT-91 and induce synthesis of keratin K17.
Epidermal keratinocytes have important immunologic functions, which is apparent during wound healing, in psoriasis, and in allergic and inflammatory reactions. In these processes, keratinocytes not only produce cytokines and growth factors that attract and affect lymphocytes but also respond to the polypeptide factors produced by the lymphocytes. Gamma inter
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10. Keratin 17 null mice exhibit age- and strain-dependent alopecia
Onset of type I keratin 17 (K17) synthesis marks the adoption of an appendageal fate within embryonic ectoderm, and its expression persists in specific cell types within mature hair, glands, and nail. We report that K17 null mice develop severe alopecia during the first week postbirth, correlating with hair fragility, alterations in follicular histology, and
Cold Spring Harbor Laboratory Press.
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11. Beta-keratins of turtle shell are glycine-proline-tyrosine rich proteins similar to those of crocodilians and birds
This study presents, for the first time, sequences of five beta-keratin cDNAs from turtle epidermis obtained by means of 5′- and 3′-rapid amplification of cDNA ends (RACE) analyses. The deduced amino acid sequences correspond to distinct glycine-proline-serine-tyrosine rich proteins containing 122–174 amino acids. In situ hybridization shows that beta-
Blackwell Science Inc.
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12. Novel Mechanism of Steroid Action in Skin through Glucocorticoid Receptor Monomers
Glucocorticoids (GCs), important regulators of epidermal growth, differentiation, and homeostasis, are used extensively in the treatment of skin diseases. Using keratin gene expression as a paradigm of epidermal physiology and pathology, we have developed a model system to study the molecular mechanism of GCs action in skin. Here we describe a novel mechanis
American Society for Microbiology.