Interruption Of Treatment
Mostrando 25-36 de 150 artigos, teses e dissertações.
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25. Peginterferon plus ribavirin and sustained virological response rate in HCV-related advanced fibrosis: a real life study
Background: Tolerance and response to antiviral HCV treatment is poor in advanced fibrosis. The aim of this study was to assess SVR rate and its predictive factors in HCV advanced fibrosis patients treated in real life with full dose PEG-IFN plus RBV and to evaluate the adverse events related to treatment. Methods: A multicentric, retrospective study was
Braz J Infect Dis. Publicado em: 2014-01
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26. Imatinib activity on Schistosoma mansoni
Imatinib, a drug used for treatment of human chronic myeloid leukaemia, due to its activity against protein kinases, has been also evaluated in vitro against Schistosoma mansoni showing high schistosomicidal activity. In the present experiments imatinib activity in vitro was confirmed at the doses of 25 µM, 50 µM and 100 µM. The first drug activity observ
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-11
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27. Adherence to treatment with imatinib in chronic myeloid leukemia: a study of the first decade of responses obtained at a Brazilian hospital
Objetive: The aim of this study was to identify the reasons for failure in adherence to imatinib mesylate treatment in chronic myeloid leukemia. Methods: A retrospective review was performed of 100 non-electronic records of patients with Ph+ chronic myeloid leukemia treated
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013-06
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28. Oral antibacterial effect of chlorhexidine treatments and professional prophylaxis in children
AIM: The primary aim of this longitudinal study was to evaluate additional effects of 4-week chlorhexidine digluconate (CHX) gel treatments to control Aggregatibacter actinomycetemcomitans counts in children after professional dental prophylaxis. Porphyromonas gingivalis and Streptococcus mutans counts were also determined to evaluate the secondary effects o
Braz. J. Oral Sci.. Publicado em: 2013-06
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29. Estudo da toxicidade muscular pelo uso de estatinas em pacientes hipercolesterolêmicos: avaliação pela espectroscopia do hidrogênio por ressonância magnética / Study of muscle toxicity by use of statins in hypercholesterolemic patients: evaluation by proton magnetic resonance spectroscopy
Cardiovascular disease is the leading cause of death in the western world and statins are the most prescribed medications for prevention and treatment. Despite being the most prescribed drugs, they are still under-used. The main cause of interruption of statin treatment is myopathy. Among the mechanisms involved in the pathophysiology of myotoxicity, deficie
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 13/11/2012
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30. Desamparo aprendido e imunização em humanos: avaliação metodológica/conceitual e uma proposta experimental / Learned helplessness and immunization in humans: methodological/conceptual evaluation and an experimental proposal
The results of learned helplessness studies with humans have been inconsistent. This is probably due to the systematic contiguity between the end of the aversive stimulus and the immediately preceding response during the uncontrollability session, which mimics an accidental control condition. Three experiments were conducted to establish a procedure with ade
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 03/09/2012
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31. Hansen's disease: a vanishing disease?
The introduction, implementation, successes and failures of multidrug therapy (MDT) in all Hansen's disease endemic countries are discussed in this paper. The high efficacy of leprosy treatment with MDT and the global reduction of prevalence led the World Health Organization, in 1991, to establish the goal of elimination of Hansen's disease (less than 1 pati
Mem. Inst. Oswaldo Cruz. Publicado em: 2012-12
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32. M2-polarized macrophages promote metastatic behavior of Lewis lung carcinoma cells by inducing vascular endothelial growth factor-C expression
OBJECTIVES: Tumor-associated macrophages that generally exhibit an alternatively activated (M2) phenotype have been linked to tumor progression and metastasis. However, the role of M2-polarized macrophages in the growth and metastasis of lung adenocarcinoma remains enigmatic. The aim of this study was to explore the effect of M2 macrophages on the proliferat
Clinics. Publicado em: 2012-08
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33. Rat testicular impairment induced by electromagnetic radiation from a conventional cellular telephone and the protective effects of the antioxidants vitamins C and E
OBJECTIVE: The aim of this study was to investigate the possible effects of electromagnetic radiation from conventional cellular phone use on the oxidant and antioxidant status in rat blood and testicular tissue and determine the possible protective role of vitamins C and E in preventing the detrimental effects of electromagnetic radiation on the testes. MAT
Clinics. Publicado em: 2012-07
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34. Treatment of snoring and sleep apnea syndrome with a removable mandibular advancement device in patients without TMD
INTRODUCTION: Among the sleep disorders reported by the American Academy of Sleep, the most common is obstructive sleep apnea-hypopnea syndrome (OSAHS), which is caused by difficulties in air passage and complete interruption of air flow in the airway. This syndrome is associated with increased morbidity and mortality in apneic individuals. OBJECTIVE: It was
Dental Press Journal of Orthodontics. Publicado em: 2012-04
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35. Durability of the first combined antiretroviral regimen in patients with AIDS at a reference center in Belo Horizonte, Brazil, from 1996 to 2005
Finding a better first antiretroviral regimen is one of the strategies used to improve span and quality of life of HIV/AIDS patients. 891 patients were followed during 24 months or until interruption/abandonment of treatment, changing regimen or death. At the end of 6 months, 69% of the patients were still being treated with the first regimen, 54% at 12 mont
Brazilian Journal of Infectious Diseases. Publicado em: 2012-02
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36. As pacientes que tiveram câncer de mama sentem-se seguras em serem seguidas sem exames complementares? / Do breast cancer patients feel safe about the follow up without supplementary exams?
Introduction: The discussion about the best way to perform the follow-up of women with breast cancer still persists and there is no consensus on best practice. International guidelines, based on randomized clinical trials suggests that periodic physical examinations and annual mammograms are sufficient and other exams that enable early detection of metastase
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 30/08/2011