Interferon Tau
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Função do interferon-tau durante o reconhecimento materno da gestação em ruminantes
O reconhecimento materno da gestação é o período em que o concepto sinaliza sua presença para a mãe. Em ruminantes, este período coincide com o alongamento do embrião e a máxima produção de interferon-tau (IFNT). O IFNT produzido pelo concepto age via parácrina no útero inibindo a expressão dos receptores de estrógenos (ESR1) e de ocitocina (O
Ciência Rural. Publicado em: 2011
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2. Esclerose multipla : mediadores da resposta inflamatoria associadas a ressonancia magnetica quantitativa / Quantitative MRI and CSF inflammatory mediators in a sample of brazilian multiple sclerosis population : a prospective study
Quantitative MRI and CSF inflammatory mediators in a sample of brazilian multiple sclerosis population: a prospective study. Multiple sclerosis (MS) is referred to as a chronic inflammatory, demyelinating, and neurodegenerative disorder of the central nervous system (CNS), with a highly variable clinical course and prognosis. This is a prospective study to i
Publicado em: 2009
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3. Sistema biológico de aumento da taxa de prenhez. Embriões partenogenéticos podem ajudar o reconhecimento materno da gestação / Biological system to increase pregnancy rate. Parthenogenetic embryos can help the maternal recognition of the gestation
Um dos objetivos deste trabalho foi avaliar e comparar a taxa de prenhez de receptoras bovinas nulíparas, após transferência de embriões fecundados in vitro ou in vivo, associados ou não a um embrião partenogenético. Um total de 239 novilhas foram utilizadas, e as médias das taxas de prenhez aos 30 (TP30d) e 60 dias (TP 60d), foram comparadas em arra
Publicado em: 2008
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4. Atividade antiviral do útero e da placenta bovina induzida pelo vírus da doença de Newcastle
Investigou-se a atividade antiviral do útero e da placenta bovina, ao longo da gestação, induzidos pelo vírus da doença de Newcastle (NDV). Explantes do endométrio e carúnculas foram colhidos do útero. Os tecidos corioamniótico, corioalantóide e cotilédones foram dissecados da placenta fetal. Os cultivos celulares foram induzidos com aproximadamen
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2007-06
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5. Antiluteolytic activity in the uterine microenvironment during the critic period to pregnancy establishment in bovines / Atividade antiluteolítica no microambiente uterino durante o período crítico para o estabelecimento da gestação em bovinos
The inhibition of pulsatile secretion of PGF2α mediated by interferon-tau (IFN) is fundamental on the maternal recognition of pregnancy, maintaining the progesterone secretion by corpus luteum. Therefore the measurement of interferon activity in the uterine microenvironment was studied. Due to a lack of assays those measure specific antiluteolytic capa
Publicado em: 2006
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6. Secreção de interferon-tau em embriões bovinos produzidos in vitro frescos e congelados
Avaliou-se a interferência da criopreservação sobre a secreção de interferon-tau (IFN-tau) por embriões bovinos produzidos in vitro. Usaram-se dois grupos de tratamentos: I) constituído por embriões não criopreservados (fresco) e II) embriões criopreservados. Os embriões, após atingirem a fase de blastocisto (fresco ou imediatamente após o desco
Arquivo Brasileiro de Medicina Veterinária e Zootecnia. Publicado em: 2005-12
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7. Differential recognition of the type I interferon receptor by interferons tau and alpha is responsible for their disparate cytotoxicities.
Interferon tau (IFN tau), originally identified as a pregnancy recognition hormone, is a type I interferon that is related to the various IFN alpha species (IFN alpha s). Ovine IFN tau has antiviral activity similar to that of human IFN alpha A on the Madin-Darby bovine kidney (MDBK) cell line and is equally effective in inhibiting cell proliferation. In thi
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8. Anti-Human Immunodeficiency Virus Activity of Tau Interferon in Human Macrophages: Involvement of Cellular Factors and β-Chemokines
Tau interferon (IFN-τ) is a noncytotoxic type I IFN responsible for maternal recognition of the fetus in ruminants. IFN-τ inhibits human immunodeficiency virus (HIV) replication more strongly than human IFN-α, particularly in human monocyte-derived macrophages. In this study performed in human macrophages, IFN-τ efficiently inhibited the early steps of t
American Society for Microbiology.
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9. Macrophages produce nitric oxide at allograft sites.
OBJECTIVE: The current study was designed to determine which cytokines produced during an alloimmune response stimulate macrophage nitric oxide (.N = O) production at allograft sites. SUMMARY BACKGROUND DATA: Previous work has demonstrated that rat sponge matrix allograft infiltrating cells produce more .N = O on stimulation with alloantigen than syngeneic g
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10. Interferon-γ Differentially Affects Alzheimer’s Disease Pathologies and Induces Neurogenesis in Triple Transgenic-AD Mice
Inflammatory processes, including the episodic and/ or chronic elaboration of cytokines, have been identified as playing key roles in a number of neurological disorders. Whether these activities impart a disease-resolving and/or contributory outcome depends at least in part on the disease context, stage of pathogenesis, and cellular milieu in which these fac
American Society for Investigative Pathology.
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11. The effects of estrogen, its antagonist ICI 182, 780, and interferon-tau on the expression of estrogen receptors and integrin alphaV beta 3 on cycle day 16 in bovine endometrium
We have shown previously that downregulation of intercaruncular stromal integrin αvβ3 in bovine endometrium on day 16 of the estrous cycle coincided with the antibody recognition of estrogen receptors (ER) in the luminal epithelium. In pregnancy, these changes were not observed. Our hypothesis was that on day 16 of the estrous cycle, estrogen from the domi
BioMed Central.
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12. Repression of Ets-2-Induced Transactivation of the Tau Interferon Promoter by Oct-4
Oct-4 is a POU family transcription factor associated with potentially totipotent cells. Genes expressed in the trophectoderm but not in embryos prior to blastocyst formation may be targets for silencing by Oct-4. Here, we have tested this hypothesis with the tau interferon genes (IFNT genes), which are expressed exclusively in the trophectoderm of bovine em
American Society for Microbiology.