Integron
Mostrando 25-36 de 220 artigos, teses e dissertações.
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25. Detection and transfer of antimicrobial resistance gene integron in Salmonella Enteritidis derived from avian material
The expansion of global poultry production has increased the need to reduce or control the agents responsible for economic losses, including Salmonella spp. These bacteria are also of public health concern due to their potential to cause food poisoning, and, more recently, due to the antimicrobial resistance presented by these bacteria. Molecular biology is
Revista Brasileira de Ciência Avícola. Publicado em: 2009-09
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26. Prevalência de beta-lactamases de amplo espectro e metilases RNAr 16S em isolados clínicos de Pseudomonas aeruginosa multirresistentes recuperados em diferentes hospitais de São Paulo / Prevalence of Extended-spectrum beta-lactamase and 16S rRNA methylases in clinical isolates of multidrug-resistant Pseudomonas aeruginosa recovered from differents hospitals in São Paulo
Introduction and aim: The production of extended-spectrum beta-lactamases (ESBLs) has been restricted to Klebsiella spp. and Escherichia coli, being associated with high rates of resistance, morbidity and mortality. Since genetic determinants for ESBLs (blaESBL genes) are mediated by plasmids, the spread to other medical important species is considered an ep
Publicado em: 2009
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27. Caracterização e epidemiologia molecular de cepas de Klebsiella pneumoniae produtoras de ESBLs isoladas de pacientes do Hospital Universitário de Londrina, no período de 2000-2004
Klebsiella pneumoniae desempenha papel importante em infecções hospitalares causando, principalmente, pneumonia, sepse, infecção urinária e de ferida cirúrgica. Os objetivos deste estudo foram: determinar os perfis de resistência a antimicrobianos, caracterizar ESBLs (ß-lactamases de espectro ampliado), avaliar a similaridade genética, comparar téc
Publicado em: 2007
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28. Metalo-beta-lactamases
Nos últimos anos tem sido observada maior incidência de bacilos Gram-negativos resistentes a cefalosporinas de espectro ampliado no ambiente hospitalar, ocasionando, assim, maior uso de betalactâmicos mais potentes, como os carbapenens. A utilização de carbapenens exerce maior pressão seletiva sobre a microbiota hospitalar, o que pode ocasionar aumento
Jornal Brasileiro de Patologia e Medicina Laboratorial. Publicado em: 2006-04
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29. Emergence of dhfrXVb and blaCARB-4 gene cassettes in class 1 integrons from clinical Pseudomonas aeruginosa isolated in Amazon region
Integrons play a role in horizontal acquisition and expression of genes, as well as gene reservoir, contributing for the resistance phenotype, particularly relevant to bacteria of clinical importance. We aimed to determine the composition and the organization of the class 1 integron variable region present in Pseudomonas aeruginosa clinical isolates from Bra
Memórias do Instituto Oswaldo Cruz. Publicado em: 2006-02
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30. Molecular Characterization of Integrons in Acinetobacter baumannii: Description of a Hybrid Class 2 Integron
Twenty Acinetobacter baumannii strains resistant to various antibiotics were analyzed for integron content and sequences of the amplification products. Sixteen clinical isolates had a class 1 integron, 2 contained an additional class 1 or class 2 integron, but no class 3 integron was detected. Thirteen strains had integrons with a single cassette: aac(3)-Ia
American Society for Microbiology.
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31. Isolation of an Integron-Borne blaVIM-4 Type Metallo-β-Lactamase Gene from a Carbapenem-Resistant Pseudomonas aeruginosa Clinical Isolate in Hungary
The first integron-borne metallo-β-lactamase gene was isolated in Hungary. The blaVIM-4 gene is located on a class 1 integron that also carries a novel blaOXA-like gene. The integron is harbored by a serotype O12 Pseudomonas aeruginosa strain and shows high structural similarity to integrons isolated in Greece and Poland.
American Society for Microbiology.
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32. Characterization of the Class 3 Integron and the Site-Specific Recombination System It Determines
Integrons capture gene cassettes by using a site-specific recombination mechanism. As only one class of integron and integron-determined site-specific recombination system has been studied in detail, the properties of a second class, the only known class 3 integron, were examined. The configuration of the three potentially definitive features of integrons, t
American Society for Microbiology.
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33. Novel Complex sul1-Type Integron in Escherichia coli Carrying blaCTX-M-9
For the present report, a novel complex class 1 integron, In60, was characterized. Part of this integron includes the blaCTX-M-9 gene and its downstream nucleotide sequence, which shares 81% and 78% nucleotide identity with those of kluA-1 β-lactamase and orf3 of K. ascorbata, respectively. Furthermore, a new insertion sequence, IS3000, has been found in In
American Society for Microbiology.
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34. Excision and Integration of Cassettes by an Integron Integrase of Nitrosomonas europaea
We found in the environmental strain Nitrosomonas europaea a chromosomal integron-like structure with an integrase gene, intINeu. We have tested the capacity of the IntINeu integrase to excise and integrate several resistance gene cassettes. The results allow us to consider IntINeu a new functional integron integrase.
American Society for Microbiology.
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35. Transposon Tn21, Flagship of the Floating Genome
The transposon Tn21 and a group of closely related transposons (the Tn21 family) are involved in the global dissemination of antibiotic resistance determinants in gram-negative facultative bacteria. The molecular basis for their involvement is carriage by the Tn21 family of a mobile DNA element (the integron) encoding a site-specific system for the acquisiti
American Society for Microbiology.
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36. Evidence for a Chromosomally Located Third Integron in Salmonella enterica Serovar Typhimurium DT104b
Salmonella enterica serovar Typhimurium isolates of phage types DT104 and DT104b are frequently associated with multiple antimicrobial resistance. We describe the characterization of a class 1 integron containing dfrA1 and aadA1, genes from two Salmonella serovar Typhimurium DT104b isolates. Genetic mapping located the integron to the bacterial chromosome in
American Society for Microbiology.