Insulin Secretion
Mostrando 1-12 de 790 artigos, teses e dissertações.
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1. The relation of dermcidin with insulin resistance and inflammation in women with polycystic ovary syndrome
SUMMARY OBJECTIVE: Polycystic ovary syndrome is the most common endocrinopathy among women of reproductive age. Polycystic ovary syndrome is a metabolic disorder associated with insulin resistance and subclinical inflammation. Dermcidin, an antimicrobial peptide, involves in insulin resistance and inflammatory processes. Dermcidin suppresses the secretion o
Revista da Associação Médica Brasileira. Publicado em: 2022
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2. Diabetes and bone
Abstract Globally, one in 11 adults has diabetes mellitus of which 90% have type 2 diabetes. The numbers for osteoporosis are no less staggering: 1 in 3 women has a fracture after menopause, and the same is true for 1 in 5 men after the age of 50 years. Aging is associated with several physiological changes that cause insulin resistance and impaired insulin
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. Leydig and Sertoli cell function in individuals with genital ambiguity, 46,XY karyotype, palpable gonads and normal testosterone secretion: a case-control study
Abstract BACKGROUND: Because normal male sexual differentiation is more complex than normal female sexual differentiation, there are more cases of disorders of sex development (DSDs) with 46,XY karyotype that have unclear etiology. However, Leydig and Sertoli cell markers are rarely used in distinguishing such individuals. OBJECTIVES: To evaluate the funct
Sao Paulo Medical Journal. Publicado em: 2022
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4. Effect of free fatty acids on insulin secretion, insulin sensitivity and incretin effect – a narrative review
ABSTRACT Deleterious effects of free fatty acids, FFAs, on insulin sensitivity are observed in vivo studies in humans. Mechanisms include impaired insulin signaling, oxidative stress, inflammation, and mitochondrial dysfunction, but the effects on insulin secretion are less well known. Our aim was to review the relationship of increased FFAs with insulin res
Arch. Endocrinol. Metab.. Publicado em: 2021-02
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5. Obesity care: more urgent than ever
ABSTRACT Deleterious effects of free fatty acids, FFAs, on insulin sensitivity are observed in vivo studies in humans. Mechanisms include impaired insulin signaling, oxidative stress, inflammation, and mitochondrial dysfunction, but the effects on insulin secretion are less well known. Our aim was to review the relationship of increased FFAs with insulin res
Arch. Endocrinol. Metab.. Publicado em: 2021-02
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6. Hypoglycemic effect of okra aqueous extract on streptozotocin-induced diabetic rats
Abstract Okra (AbelmoschusesculentusL.Moench) is widely planted in subtropical and tropical areas, with good palatability and a variety of biological activities. However, the hypoglycemic activity of okra aqueous extract and its mechanism were still unclear. In this paper, the hypoglycemic effect of okra aqueous extract on type 1 diabetic rats induced by str
Food Sci. Technol. Publicado em: 2020-12
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7. News for a New Year
ABSTRACT Objective Provide a comprehensive view of the events surrounding the sugar consumption, under conditions of energy equivalence; through the analysis of behavioral aspects of intake, and of biochemical, metabolic and physiological parameters, as well as the effect of this nutrient on the plasticity of adipose tissue. Materials and methods Newly wea
Arch. Endocrinol. Metab.. Publicado em: 2020-02
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8. High-sugar diet leads to obesity and metabolic diseases in ad libitum -fed rats irrespective of caloric intake
ABSTRACT Objective Provide a comprehensive view of the events surrounding the sugar consumption, under conditions of energy equivalence; through the analysis of behavioral aspects of intake, and of biochemical, metabolic and physiological parameters, as well as the effect of this nutrient on the plasticity of adipose tissue. Materials and methods Newly wea
Arch. Endocrinol. Metab.. Publicado em: 2020-02
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9. Insulin signaling in the whole spectrum of GH deficiency
ABSTRACT GH is one of the insulin counterregulatory hormones which acts in the opposite way to insulin, increasing the glucose production by the liver and kidneys and decreasing glucose uptake from peripheral tissues, thus being a hyperglycemic hormone. When in excess, as in acromegaly, it induces glucose intolerance and diabetes. As expected, patients with
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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10. Update on new GH-IGF axis genetic defects
ABSTRACT The somatotropic axis is the main hormonal regulator of growth. Growth hormone (GH), also known as somatotropin, and insulin-like growth factor 1 (IGF-1) are the key components of the somatotropic axis. This axis has been studied for a long time and the knowledge of how some molecules could promote or impair hormones production and action has been g
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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11. Laboratory investigations in the diagnosis and follow-up of GH-related disorders
ABSTRACT In addition to auxiological, clinical and metabolic features measurements of growth hormone (GH) and insulin-like growth factor I (IGF-I) complement our tools in diagnosis and follow-up of GH-related disorders. While comparably robust during the pre-analytical phase, measurement and interpretation of concentrations of both hormones can be challengin
Arch. Endocrinol. Metab.. Publicado em: 10/01/2020
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12. Effects of Dietary Energy Concentration on Reproductive Hormone Secretion and Gene Expression in the Hypothalamus-Pituitary-Gonad Axis in Laying Geese
ABSTRACT The objective of the study was to investigate the mechanism by which dietary energy concentration regulates laying performance in geese. Eighty 558-day-old female Sichuan White geese were randomly allotted to two dietary treatments, each treatment was fed 1 of 2 experimental diets containing 10.00 (deficient) or 11.80MJ/kg metabolizable energy (suff
Braz. J. Poult. Sci.. Publicado em: 11/11/2019