Inhibitors
Mostrando 1-12 de 10325 artigos, teses e dissertações.
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1. Pode-se utilizar inibidores da enzima conversora de angiotensina (inibidores da ECA) como captopril ou enalapril ou bloqueadores do receptor de angiotensina (BRA) como losartana em pacientes que apresentam insuficiência renal crônica com albuminúria ou associada a diabetes tipo 2?
O uso de inibidores da ECA e BRA não é contraindicado em pacientes que apresentam insuficiência renal crônica com albuminúria ou associada a diabetes. Pelo contrário, nesses pacientes, essas medicações podem e devem ser utilizadas, pois diminuem a excreção urinária de proteínas e retardam a progressão da doença renal.
Para a maioria do
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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2. Como manejar pacientes com indicação de uso de antiplaquetários que tiveram sangramento digestivo alto?
O uso de AAS em dose baixa (até 100 mg) associado ao uso contínuo de inibidor da bomba de prótons (IBP) é a estratégia preferencial para prevenção secundária de eventos cardiovasculares. AAS tamponado não é eficaz para redução de sangramentos. Em pacientes com infecção por Helicobacter Pylori, deve-se indicar também a erradicação.
O
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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3. Como tratar a depressão na gestação?
A indicação de tratamento da depressão maior unipolar na gestação é estabelecida conforme a gravidade do quadro depressivo: está indicado psicoterapia em casos leves a moderados (cinco a seis sintomas depressivos e sem sinais de gravidade) e farmacoterapia em casos graves (sete a nove sintomas depressivos). Pacientes com sinais de gravidade, como r
Núcleo de Telessaúde Rio Grande do Sul. Publicado em: 12/06/2023
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4. Qual o protocolo para atendimento odontológico ao paciente com diabetes mellitus e doença periodontal?
No que se refere ao atendimento odontológico de paciente com diabetes mellitus (DM) e doença periodontal, os estudos têm demonstrado que o tratamento da periodontite por meio da terapia mecânica convencional (raspagem e alisamento radicular), além de promover a melhora na saúde periodontal é capaz de também promover melhorias na saúde sistêmica.
Núcleo de Telessaúde Amazonas. Publicado em: 12/06/2023
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5. Increased expression of matrix metalloproteinases 2 and 9 as poor prognosis factor for Hodgkin’s lymphoma patients
Abstract Objective: The aim of our study was to evaluate the expression of MMP-2 and MMP-9 as a prognostic factor in patients diagnosed with Hodgkin Lymphoma (HL). Methods: In the present study, 45 paraffin biopsies from patients up to 19 years old diagnosed with HL were used in two referral hospitals in the state of Pernambuco, Brazil. Risk groups were cl
Jornal de Pediatria. Publicado em: 2023
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6. Dose-ranging effects of SGLT2 inhibitors in patients with type 2 diabetes: a systematic review and meta-analysis
ABSTRACT The lowest dosage of empagliflozin (10 mg) showed similar benefits on glycated hemoglobin (HbA1c) level, body weight, blood pressure, and total and cardiovascular mortality in comparison with the highest available dose (25 mg) in the EMPAREG trial. These findings have not been clearly demonstrated for canagliflozin and dapagliflozin. The objective w
Archives of Endocrinology and Metabolism. Publicado em: 2022
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7. Sulfonylurea resistance in Amaranthus hybridus from southern Brazil
ABSTRACT Amaranthus hybridus is a C4 broadleaf species widely spread across Brazilian agricultural territory. Recently, several herbicide resistance reports have been documented in southern Brazil, including the reports for enolpyruvilshikymate-3-phosphate (EPSPS)- and acetolactate-synthase (ALS)- inhibitors. The objective of this study was to confirm the ex
Revista Ceres. Publicado em: 2022
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8. Vaccine responses in patients with chronic lymphocytic leukemia on treatment with Bruton Tyrosine Kinase Inhibitors: a focused review
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
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9. 2-(Pyridin-4yl)benzothiazole and Its Benzimidazole-Analogue: Biophysical and in silico Studies on Their Interaction with Urease and in vitro Anti-Helicobacter pylori Activities
In this study, the interaction between benzothiazole (BTA, concentration of a drug required for 50% inhibition in vitro (IC50) = 0.77 mM) and benzimidazole (BIA, IC50 = 2.14 mM) with urease was quantitatively assessed, using UV-Vis, molecular fluorescence, and circular dichroism. The results showed that both compounds interact with urease by a static fluores
Journal of the Brazilian Chemical Society. Publicado em: 2022
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10. Discovery of Thiopyrimidinone Derivatives as a New Class of Human Aldose Reductase Inhibitors
Diabetes is a chronic metabolic disorder characterized by insufficient insulin production, the cells’ inability to use this insulin, or a combination of both, leading to secondary complications such as diabetic neuropathy and retinopathy. One way to prevent or control such complications is the use of aldose reductase (AR) inhibitors. In this work, we synth
Journal of the Brazilian Chemical Society. Publicado em: 2022
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11. Treatment-resistant bipolar depression: concepts and challenges for novel interventions
Treatment-resistant bipolar depression (TRBD) has been reported in about one-quarter of patients with bipolar disorders, and few interventions have shown clear and established effectiveness. We conducted a narrative review of the published medical literature to identify papers discussing treatment-resistant depression concepts and novel interventions for bip
Brazilian Journal of Psychiatry. Publicado em: 2022
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12. What is the cause of low seed germination of Zanthoxylum rhoifolium Lam.?
ABSTRACT This study aimed to determine the main causes of low germination of Zanthoxylum rhoifolium Lam. (Rutaceae) seeds. Initially, the physical and physiological qualities were evaluated in seeds from four areas (lots) (Step I). Then, tests were performed (Step II) to determine physical dormancy (imbibition in water and methylene blue), physiological (ger
Revista Ceres. Publicado em: 2022