Inhibin
Mostrando 1-12 de 47 artigos, teses e dissertações.
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1. Leydig and Sertoli cell function in individuals with genital ambiguity, 46,XY karyotype, palpable gonads and normal testosterone secretion: a case-control study
Abstract BACKGROUND: Because normal male sexual differentiation is more complex than normal female sexual differentiation, there are more cases of disorders of sex development (DSDs) with 46,XY karyotype that have unclear etiology. However, Leydig and Sertoli cell markers are rarely used in distinguishing such individuals. OBJECTIVES: To evaluate the funct
Sao Paulo Medical Journal. Publicado em: 2022
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2. Maternal exposure to trace cadmium affects gonadal differentiation and development in male offspring rats though a star pathway
Abstract To investigate effect and mechanism of maternal exposure to trace cadmium on the differentiation and development in testis of male offspring rats. Thirty-two pregnant female SD rats were randomly divided into 4 groups: CdCl2 treated group (group A) was intraperitoneally injected with CdCl2 (1.5 mg/kg.d); DES group(group B) was subcutaneously injecte
Food Sci. Technol. Publicado em: 2021-09
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3. Effect of bacterial endotoxin lipopolysaccharide treatment on duck Leydig cells
Abstract This study aimed to investigate the effects of bacterial endotoxin lipopolysaccharide (LPS) on hormone production and gene expression in duck Leydig cells and its underlying mechanisms. Leydig cells were collected from 200-day-old mallard ducks and divided into five treatment groups (0, 50, 100, 200, and 400 ng/mL LPS). After treatment with LPS for
Anim. Reprod.. Publicado em: 25/11/2019
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4. Transforming growth factor-beta family members are regulated during induced luteolysis in cattle
Abstract The transforming growth factors beta (TGFβ) are local factors produced by ovarian cells which, after binding to their receptors, regulate follicular deviation and ovulation. However, their regulation and function during corpus luteum (CL) regression has been poorly investigated. The present study evaluated the mRNA regulation of some TGFβ family l
Anim. Reprod.. Publicado em: 25/11/2019
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5. Steroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation
OBJECTIVE: To analyze steroidogenesis-related gene expression in the rat ovary exposed to melatonin supplementation. METHODS: Thirty-two virgin adult female rats were randomized to two groups as follows: the control group GI received vehicle and the experimental group GII received melatonin supplementation (10 µg/night per animal) for 60 consecutive days.
Clinics. Publicado em: 2015-02
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6. Efeitos da ativina A, inibina A e folistatina Sobre células endometriais em um modelo de adesão e invasão peritoneal in vitro.
Objective: The aim of this study was to investigate whether activin A has an effect in the attachment and invasion of endometrial cells in a modeled peritoneum in vitro. Methods: Cultured endometrial stromal and epithelial cells were treated with activin A (concentration range 6.25 to 50 ng/ml) and with activin A 25 ng/ml alone or associated to inhibin A or
Publicado em: 2007
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7. Geração de inibina A após estímulo gonadotrófico: novo método de detecção de tecido ovariano em pacientes com anomalia da diferenciação sexual / Inhibin A generation after gonadotropin stimulus: a new method to detect ovarian tissue in true hermaphrodites
Introduction: True hermaphrodism (TH) is characterized by the presence of ovarian and testicular tissue in the same patient comprises 5% of the intersex cases. A large spectrum of phenotypical variation is observed, ranging from normal female genitalia to normal male genitalia, covering a wide range of intermediary presentations, it becomes very difficult to
Publicado em: 2006
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8. Study of the diabetes mellitus on testicular function of Wistar rat / Efeitos do diabetes mellitus sobre a função testicular de ratos Wistar
Utilizaram-se 27 ratos Wistar, machos com 98 dias de idade, originados do Biotério da FMVZ-USP, com o objetivo de avaliar os possíveis efeitos do diabetes mellitus, sobre a função reprodutiva relacionada ao macho.Os animais foram divididos em três grupos, grupo A (GA) constituído de 10 animais sadios, grupo B (GB) constituído de oito ratos Wistar, com
Publicado em: 2006
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9. Human seminal alpha inhibins: isolation, characterization, and structure.
Two additional peptides with inhibin-like activity have been isolated from human seminal plasma. One consists of 52 amino acids and the other, 92 amino acids. They are designated alpha-inhibin-52 and alpha-inhibin-92. Sequence analyses show that the NH2-terminal 31 amino acids of alpha-inhibin-52 are identical to the structure of the inhibin-like peptide pre
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10. Endogenous Betaglycan Is Essential for High-Potency Inhibin Antagonism in Gonadotropes
Inhibins are endocrine hormones that regulate gametogenesis and reproduction through a negative feedback loop with FSH. Inhibin action involves antagonism of signaling by activin or other TGFβ family ligands. In transfection assays, antagonism by inhibin can be potentiated by betaglycan, a coreceptor for selected TGFβ family ligands. We tested whether beta
The Endocrine Society.
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11. Secretion of follicle-stimulating hormone and production of inhibin are reciprocally related.
The production of inhibin in cultured granulosa cells from immature hypophysectomized, estrogen-treated rats and Sertoli cells from normal animals was determined by a specific radioimmunoassay using an antiserum against a synthetic replicate of [Tyr30]inhibin alpha-chain-(1-30). The amount of immunoreactive inhibin detected in the spent media of these cells
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12. Gonadal and extragonadal expression of inhibin alpha, beta A, and beta B subunits in various tissues predicts diverse functions.
The S1-nuclease analysis was used to investigate the pattern of inhibin expression in the rat. In a first series of experiments, expression of the alpha, beta A, and beta B subunits of inhibin were monitored in various tissues from male and female rats. Two observations emerge from these studies. First, expression of inhibin subunits was found in gonadal and