Imidazol
Mostrando 1-12 de 90 artigos, teses e dissertações.
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1. IMIDAZOL E CATÁLISE: UM PAR PERFEITO
The imidazole (IMZ) ring presents several chemical properties that turns it into a versatile acid-basic/nucleophilic catalyst. The discovery of the biological properties of histidine (amino acid with IMZ ring) instigates the study of this class of compounds. It is found in nature in several enzymes such as chymotrypsin and RNAses due to these properties. Thi
Quím. Nova. Publicado em: 2021-03
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2. Antimicrobial Effects of Silver(I) and Bismuth(III) Complexes with Secnidazole-Derived Schiff Base Ligands: the Role of the Nitro Group Reduction
[Ag(HL)NO3] complexes (1-4) were obtained with (E)-N’-(1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ylidene)acetohydrazide (HL1); (E)-N’-(1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ylidene)benzohydrazide (HL2); (E)-2-(1-(2-methyl-5-nitro-1H-imidazol-1-yl)propan-2-ylidene)hydrazinecarbothioamide (HL3) and (E)-N-methyl-2-(1-(2-methyl-5-nitro-1H-imidazo
J. Braz. Chem. Soc.. Publicado em: 24/10/2019
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3. Pyrazolyl-Tetrazoles and Imidazolyl-Pyrazoles as Potential Anticoagulants and their Integrated Multiplex Analysis Virtual Screening
This article reports a novel virtual screening algorithm seeking the rational identification of novel lead anticoagulants. Seven 5-(3-methyl-1-aryl-1H-pyrazol-4-yl)-1H-tetrazoles and seven novel 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-3-methyl-1H-pyrazoles were obtained in three steps starting from arylhydrazine hydrochlorides as raw materials in good yields
J. Braz. Chem. Soc.. Publicado em: 2019-01
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4. Experimental and Theoretical Study of Corrosion Inhibition of Mild Steel in 1.0 M HCl Medium by 2(-4( hloro phenyl-1H- benzo[d]imidazol)-1-yl)phenyl)methanone
The 2(-4(chloro phenyl-1H- benzo[d]imidazol)-1-yl)phenyl)methanone (CBIPM) was synthesized and tested as a corrosion inhibitor for mild steel in 1.0 M HCl solution using electrochemical and spectroscopy measurements. Results obtained showed that this compound has a good inhibition properties for mild steel corrosion in acidic medium which its inhibition effi
Mat. Res.. Publicado em: 06/12/2018
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5. Studies on new substituted pyridazinones: synthesis and biological evaluation
We report herein the synthesis and pharmacological evaluation of a new series of 6-aryl-2-(imidazol-1-yl/1,2,4-triazol-1-yl)-2-methyl-4,5-dihydro-(2H)-pyridazin-3-one (3a-j) as potential anticonvulsant and antitubercular agents. The title compounds were prepared by reacting 6-aryl-4,5-dihydro-(2H)-pyridazin-3-one (2a-e) with formaldehyde and secondary cyclic
Braz. J. Pharm. Sci.. Publicado em: 29/11/2018
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6. ESTUDO COMPUTACIONAL DE 1H-IMIDAZOL-2-IL-PIRIMIDINA-4,6-DIAMINAS PARA A IDENTIFICAÇÃO DE POTENCIAIS PRECURSORES DE NOVOS AGENTES ANTIMALÁRICOS
The aim of this study was develop in silico studies with a data set of 1 H -imidazol-2-yl-pyrimidine-4,6-diamines derivatives described as antimalarial agents with the intention of obtain data and tools useful in the development of new drugs of this class. A QSAR model was developed using topological, geometrical and electronic molecular descriptors with aid
Quím. Nova. Publicado em: 2016-06
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7. Aqueous Micelles as Catalytic Nanoreactors for Dephosphorylation Reactions
A reação entre um novo derivado de imidazol, 3,5-bis((1H-imidazol-1-il)metil)anilina (BIm), e o triéster de fosfato dietil 2,4-dinitrofenil fosfato (DEDNPP), que procede por um mecanismo SN2(P), é substancialmente acelerada em presença do surfactante catiônico brometo de cetiltrimetrilamônio (CTAB) e do surfactante aniônico dodecil sulfato de sódio
J. Braz. Chem. Soc.. Publicado em: 2014-12
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8. Synthesis and characterization of novel polyamide-ethers based on bis-imidazole containing bulky aryl pendant groups
A series of novel polyamide-ethers (PAEs) based on bis-imidazole containing bulky aryl pendant groups was prepared by direct polycondensation of a diamine, 4-(1-(4-(4-(2-(4-aminophenyl)-4,5-diphenyl-1H-imidazol-1-yl)phenoxy)phenyl)-4,5-diphenyl-1H-imidazol-2-yl)benzenamine (DABI), and various dicarboxylic acids. All the resulting polyamide-ethers were amorph
Polímeros. Publicado em: 27/08/2013
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9. Síntese e caracterização de sistemas orgânicos semicondutores baseados em tiofeno-fenileno para aplicação em células fotovoltaicas
A combinação, intensificação ou surgimento de novas propriedades em sistemas molecularmente arquitetados e híbridos π-conjugados pode ser estrategicamente explorado na construção de dispositivos optoeletrônicos e produtores e armazenadores de energia. Este trabalho de tese, fruto de uma colaboração multidisciplinar, focaliza a síntese, a cara
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 17/09/2012
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10. LIBS e nanopartículas fluorescentes : novas estratégias para determinação de íons Cu(II) em águas / LIBS and fluorescent nanoparticles : new strategies for the determination of Cu(II) ions in water
Neste trabalho diferentes fases sensoras foram desenvolvidas para implementar novas estratégias para a determinação de íons cobre em águas naturais, empregando Espectroscopia Óptica de Emissão em Plasma Induzido por Laser (LIBS) e Espectroscopia de Luminescência. Nas determinações por LIBS, membranas de PVC plastificadas foram empregadas para extra
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 18/04/2012
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11. Novas estratégias de purificação dos fatores de coagulação Fator VIII e Proteína C a partir de plasma humano empregando cromatografia líquida. / New strategies of purification of coagulation Factor VIII and Protein C from human plasma using liquid chromatography.
Neste trabalho estudou-se a purificação de fator VIII de coagulação (FVIII) e da Proteína C (PC) por cromatografia. Em coluna ANX Sepharose FF como primeira etapa de purificação do plasma permite a eluição do FVIII e da PC com bom fator de purificação, mas não a separação destas. Propomos a separação de FVIII e PC empregando cromatografia de
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 19/03/2012
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12. Copolymer of acrylonitrile and vinyl-imidazole from the chemical modification of polyacrylonitrile / Obtenção do copolímero de acrilonitrila e vinil-imidazol a partir da modificação química da poliacrilonitrila
Polymers containing heterocyclic rings such as imidazole, have a great scientific and commercial interest due to its use in several areas. Such polymers can be obtained by chemical modification of polymers such as polyacrylonitrile commercial. Generally, this type of reaction is carried out by conventional heating (thermal). However, more recently, the micro
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 28/02/2012