Hydroxychloroquine
Mostrando 13-24 de 45 artigos, teses e dissertações.
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13. The evaluation of the Myxovirus Resistance 1 protein in serum and saliva to monitor disease activation in primary Sjögren’s syndrome
OBJECTIVE: Primary Sjögren’s syndrome (pSjS) is a chronic autoimmune disease that causes dry eye and mouth. No laboratory parameters to monitor the activation of this disease have been identified. Therefore, any possible relationships between salivary and blood myxovirus resistance 1 (MX1) and pSjS must be prospectively studied. METHODS: Thirty female p
Clinics. Publicado em: 19/06/2019
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14. Eosinophilic fasciitis: an atypical presentation of a rare disease
RESUMO A fasciite eosinofílica ou doença de Shulman é uma doença rara de etiologia desconhecida. É caracterizada por eosinofilia periférica, hipergamaglobulinemia e velocidade de sedimentação eritrocitária elevada. O diagnóstico é confirmado por biópsia profunda da pele. O tratamento de primeira linha é a corticoterapia. Apresentamos um caso rar
Rev. Assoc. Med. Bras.. Publicado em: 11/04/2019
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15. Hydroxychloroquine ototoxicity in a patient with systemic lupus erythematosus
An. Bras. Dermatol.. Publicado em: 2018-06
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16. Acute generalized exanthematous pustulosis induced by hydroxychloroquine: a case with atypical clinical presentation
Abstract Acute generalized exanthematous pustulosis is a rare drug-induced eruption that is characterized by acute, nonfollicular sterile pustules on an erythematous and edematous base. The most frequently implicated drugs are beta-lactam antibiotics. Hydroxychloroquine has been widely used to treat dermatologic and rheumatologic diseases and has been report
An. Bras. Dermatol.. Publicado em: 2017-06
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17. Bullous systemic lupus erythematosus in a 10-year-old child
Abstract: Bullous systemic lupus erythematosus (BSLE) is a rare autoimmune subepidermal blistering disease, with few cases described in childhood. It has different clinical-pathological features. We report a case of BSLE in a 10-year-old child with systemic lupus erythematosus, treated with prednisone and hydroxychloroquine. There was complete remission with
An. Bras. Dermatol.. Publicado em: 2017
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18. Extensive bullous lichen sclerosus et atrophicus
Abstract Lichen sclerosus et atrophicus is a chronic disease of unknown etiology characterized by atrophic and sclerotic plaques in both genital and extragenital regions. Extensive bullous lichen sclerosus et atrophicus (BLSA) is a severe variant of the disease with no widely accepted treatment. We present a 63-year-old woman with extensive extragenital, ivo
An. Bras. Dermatol.. Publicado em: 2016-10
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19. Eosinophilic annular erythema in childhood - Case report
Abstract: Eosinophilic annular erythema is a rare, benign, recurrent disease, clinically characterized by persistent, annular, erythematous lesions, revealing histopathologically perivascular infiltrates with abundant eosinophils. This report describes an unusual case of eosinophilic annular erythema in a 3-year-old female, requiring sustained doses of hydro
An. Bras. Dermatol.. Publicado em: 2016-08
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20. Hydroxychloroquine decreases Th17-related cytokines in systemic lupus erythematosus and rheumatoid arthritis patients
OBJECTIVES: Hydroxychloroquine is an antimalarial agent that has been used in systemic lupus erythematosus and rheumatoid arthritis treatment for many years. Recently, novel mechanisms of action have been proposed, thereby broadening the therapeutic perspective of this medication. The purpose of this study was to evaluate the immunomodulatory activity of hy
Clinics. Publicado em: 2013-06
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21. Enantioselective metabolism of hydroxychloroquine employing rats and mice hepatic microsomes
A hidroxicloroquina (HCQ) é um importante fármaco quiral usado, principalmente, no tratamento de artrite reumatóide, lupus eritematoso sistêmico e malária e cujas propriedades farmacocinéticas e farmacodinâmicas parecem ser estereosseletivas. Em relação às propriedades farmacocinéticas, alguns estudos prévios indicam que a estereosseletividade po
Brazilian Journal of Pharmaceutical Sciences. Publicado em: 2009-12
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22. AVALIAÇÃO DE PARÂMETROS CLÍNICOS E QUIMIOCINAS ANTES E APÓS TRATAMENTO COM HIDROXICLOROQUINA EM PACIENTES COM ARTROSE SINTOMÁTICA DE JOELHOS
This study assessed the clinical and biological responses of patients with primary and symptomatic knee osteoarthritis (OA) to hydroxychloroquine. (HCQ) Clinical impact was assessed through Western Ontario and McMaster Universities Index (WOMAC), Lequesne-algofunctional index, and visual analog scale (VAS). Monocyte chemoattractant protein-1 (MCP-1), interle
Publicado em: 2008
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23. Microextraction techniques applied to the stereoselective analysis of ibuprofen, hydroxychloroquine and their metabolites in human urine. / Técnicas de microextração aplicadas à análise estereosseletiva do ibuprofeno, da hidroxicloroquina e de seus metabólitos em urina
The stereoselective analysis has been standing out in several areas, and it is mainly present in the pharmaceutical industry, since many drugs are marketed as racemic mixtures. The stereoselective analysis employing high-performance liquid chromatography (HPLC) and capillary electrophoresis (CE) is very useful for the determination of enantiomers at very low
Publicado em: 2007
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24. High-Performance Liquid Chromatography and Capillary Electrophoresis avaliation in the in vitro study of hydroxychloroquine enantioselective metabolism. / Avaliação da Cromatografia Líquida de Alta Eficiência e Eletroforese Capilar no Estudo in vitro do Metabolismo Enantiosseletivo da Hidroxicloroquina
A hidroxicloroquina (HCQ) é um importante fármaco quiral usado, principalmente, no tratamento de artrite reumatóide, lupus eritematoso sistêmico e malária e cujas propriedades farmacocinéticas e farmacodinâmicas são estereosseletivas. Em relação às propriedades farmacocinéticas, alguns estudos prévios indicam que o metabolismo estereosseletivo p
Publicado em: 2006