Host Regulation
Mostrando 13-24 de 1051 artigos, teses e dissertações.
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13. Host response mechanisms in periodontal diseases
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm, including Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Tannerella forsythia and Treponema denticola that trigger innate, inflammatory, and adaptive immune respon
J. Appl. Oral Sci.. Publicado em: 2015-06
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14. Translational research into gut microbiota: new horizons on obesity treatment: updated 2014
Obesity is currently a pandemic of worldwide proportions affecting millions of people. Recent studies have proposed the hypothesis that mechanisms not directly related to the human genome could be involved in the genesis of obesity, due to the fact that, when a population undergoes the same nutritional stress, not all individuals present weight gain related
Arch. Endocrinol. Metab.. Publicado em: 2015-04
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15. The rapid and sustained responses of dendritic cells to influenza virus infection in a non-human primate model
Dendritic cells (DCs) are readily infected by influenza viruses and play a crucial role in regulating host innate and adaptive immune responses to viral infection. The aims of this study are to characterize the dynamic changes in the numbers and maturation status of dendritic cells present in the lung and lung-associated lymph nodes (LALNs) in the model of a
Braz J Infect Dis. Publicado em: 2014-08
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16. Leishmania amazonensis exhibits phosphatidylserine-dependent procoagulant activity, a process that is counteracted by sandfly saliva
Leishmania parasites expose phosphatidylserine (PS) on their surface, a process that has been associated with regulation of host's immune responses. In this study we demonstrate that PS exposure by metacyclic promastigotes of Leishmania amazonensis favours blood coagulation. L. amazonensis accelerates in vitro coagulation of human plasma. In addition, L. am
Mem. Inst. Oswaldo Cruz. Publicado em: 2013-09
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17. Differential gene expressions of the MAPK signaling pathway in enterovirus 71-infected rhabdomyosarcoma cells
BACKGROUND: Mitogen-activated protein kinase (MAPK) signaling pathway plays an important role in response to viral infection. The aim of this study was to explore the function and mechanism of MAPK signaling pathway in enterovirus 71 (EV71) infection of human rhabdomyosarcoma (RD) cells. METHODS: Apoptosis of RD cells was observed using annexin V-FITC/PI bin
Braz J Infect Dis. Publicado em: 2013-08
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18. Genetic polymorphism and immune response to tuberculosis in indigenous populations: a brief review
We systematically reviewed studies of the immune response to tuberculosis and the genetic polymorphisms associated with Th1-or Th2-mediated cytokine expression in indigenous populations. A bibliographic search was performed on the Medline and ISI databases and included studies published between January 1980 and October 2011. The search terms were tuberculosi
Braz J Infect Dis. Publicado em: 2013-06
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19. Evaluation of CD4+CD25+ T lymphocyte response time kinetics in patients with chronic Chagas disease after in vitro stimulation with recombinant Trypanosoma cruzi antigens
Introduction CD4+CD25+ T lymphocytes have been implicated in the regulation of host inflammatory response against Trypanosoma cruzi, and may be involved in the clinical course of the disease. Methods Peripheral blood mononuclear cells from patients with chronic Chagas disease were cultured in the presence of T. cruzi recombinant antigens and assayed for l
Rev. Soc. Bras. Med. Trop.. Publicado em: 10/05/2013
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20. Immunological characteristics of mesenchymal stem cells
Although bone marrow is the main source, mesenchymal stem cells have already been isolated from various other tissues, such as the liver, pancreas, adipose tissue, peripheral blood and dental pulp. These plastic adherent cells are morphologically similar to fibroblasts and have a high proliferative potential. This special group of cells possesses two essenti
Rev. Bras. Hematol. Hemoter.. Publicado em: 2013
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21. Explorando as interações hospedeiro-parasitoide para a identificação de moléculas com potencial biotecnológico / Exploiting the host parasitoid interactions for the identification of molecules with biotechnological potential
Parasitoides criam condições favoráveis para seu desenvolvimento regulando processos fisiológicos do hospedeiro via a utilização de moléculas produzidas por tecidos maternos ou por tecidos derivados do parasitoide imaturo ou de simbiontes associados (vírus de poliDNA - PDV). Assim, essas moléculas se destacam como uma fonte preciosa para o desenvolv
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/04/2012
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22. Influência do Gene pacC na Regulação de Manosiltransferases no Dermatófito Trichophyton rubrum em Função de Variações Nutricionais e pH Ambiente. / Influence of Gene pacC in Mannosiltransferase Regulation of the Dermathophyte Trichophyton rubrum in Function to Changes by pH and Nutrient Sources.
Gene expression regulation is essential for fungi to adapt to environmental adversities, such as changes in the extracellular pH, nutrient starvation, ionic strength, and temperature. The adaptive response to ambient pH is well characterized in model fungi such as Aspergillus nidulans, and involves the signal transduction pathway consisting of the products o
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 02/12/2011
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23. Efeito de ExoU na ativação de NF-κB e na secreção de IL-8 por células humanas infectadas por Pseudomonas aeruginosa / Effect of Exou on the activation of the NF-κB and the secretion of the IL-8 in human cells infected with Pseudomonas
ExoU, a cytotoxin produced by the opportunistic pathogen Pseudomonas aeruginosa that is translocated into host cell cytosol by the type three secretory system, has been associated with severity of acute infections. We have previously described the potent ExoU proinflammatory activity, which accounts for a market recruitment of neutrophils to infected tissues
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/07/2011
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24. Localização genômica e subcelular dos membros da família de fosfatidilinositol quinases em Trypanosoma cruzi / Genomic and subcellular localization of the members of phosphatidylinositol kinase family in Trypanosoma cruzi
The identification of signaling molecules and the elucidation of signal transduction processes of Trypanosoma cruzi are required for understanding the host-parasite interaction and physiological processes of the parasite. However, little is yet known about signal transduction and signaling pathways that occur in the parasite, since most efforts focused on si
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 27/07/2011