Hnf 1a
Mostrando 1-12 de 259 artigos, teses e dissertações.
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1. Qual diferença entre dalteparina e enoxaparina em relação à eficácia e segurança no tratamento de trombose venosa profunda durante a gestação e puerpério?
Não há diferença significativa entre dalteparina e enoxaparina em relação à eficácia e segurança no tratamento de trombose venosa profunda (TVP) [A]
. Ambas são heparina de baixo peso molecular (HBPM) e podem ser utilizadas para tratamento de trombose venosa profunda em gestantes e puérperas
, porém a dalteparina não deve ser usada
Núcleo de Telessaúde Santa Catarina. Publicado em: 12/06/2023
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2. Granuloma annulare and necrobiosis lipoidica in a patient with HNF1A-MODY
SUMMARY Maturity-onset diabetes of the young (MODY) is a heterogeneous group of monogenic forms of diabetes mellitus with distinct clinical features. Clinical dermatological phenotypes in MODY patients are very rare in literature. This report describes a patient with HNF1A-MODY presenting with necrobiosis lipoidica (NL) and granuloma annulare (GA). A 39-year
Archives of Endocrinology and Metabolism. Publicado em: 2022
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3. When do we need to suspect maturity onset diabetes of the young in patients with type 2 diabetes mellitus?
ABSTRACT Objetivo: Maturity onset diabetes of the young (MODY) patients have clinical heterogeneity as shown by many studies. Thus, often it is misdiagnosed to type 1 or type 2 diabetes(T2DM). The aim of this study is to evaluate MODY mutations in adult T2DM patients suspicious in terms of MODY, and to show clinical and laboratory differences between these
Archives of Endocrinology and Metabolism. Publicado em: 2022
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4. MODY probability calculator for GCK and HNF1A screening in a multiethnic background population
ABSTRACT Objective We aimed to identify the frequency of monogenic diabetes, which is poorly studied in multiethnic populations, due to GCK or HNF1A mutations in patients with suggestive clinical characteristics from the Brazilian population, as well as investigate if the MODY probability calculator (MPC) could help patients with their selection. Subjects
Arch. Endocrinol. Metab.. Publicado em: 2020-02
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5. MODY probability calculator for GCK and HNF1A screening in a multiethnic background population
ABSTRACT Objective We aimed to identify the frequency of monogenic diabetes, which is poorly studied in multiethnic populations, due to GCK or HNF1A mutations in patients with suggestive clinical characteristics from the Brazilian population, as well as investigate if the MODY probability calculator (MPC) could help patients with their selection. Subjects
Arch. Endocrinol. Metab.. Publicado em: 30/09/2019
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6. Searching for mutations in the HNF1B gene in a Brazilian cohort with renal cysts and hyperglycemia
ABSTRACT Objective To verify the presence of variants in HNF1B in a sample of the Brazilian population selected according to the presence of renal cysts associated with hyperglycemia. Subjects and methods We evaluated 28 unrelated patients with clinical suspicion of HNF1B mutation because of the concomitant presence of diabetes mellitus (DM) or prediabet
Arch. Endocrinol. Metab.. Publicado em: 02/05/2019
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7. The Occurrence of Primary Hepatic Adenoma in Deceased Donor Renal Transplant Recipient
Main findings: We reported a case of new-onset, multi-focal hepatic adenoma in an 18 year-old man with no classic risk factors occurring forty months after a renal transplant from a cadaver donor. Histopathology of the adenoma was examined and genotype and phenotype were also analyzed. Histopathologic examination of the adenoma showed no malignancy. Genotyp
Int. braz j urol.. Publicado em: 2014-01
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8. Protozoans bacterivory in a subtropical environment during a dry/cold and a rainy/warm season
In aquatic ecosystems, bacteria are controlled by several organisms in the food chain, such as protozoa, that use them as food source. This study aimed to quantify the ingestion and clearance rates of bacteria by ciliates and heterotrophic nanoflagellates (HNF) in a subtropical freshwater reservoir (Monjolinho reservoir -São Carlos -Brazil) during one year
Braz. J. Microbiol.. Publicado em: 2014
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9. INVESTIGAÇÃO DE MODY 3 EM PACIENTES DO AMBULATÓRIO DE DM 1 DO HOSPITAL UNIVERSITÁRIO DA UNIVERSIDADE FEDERAL DO MARANHÃO (HUUFMA) / INVESTIGATION OF MODY 3 IN PATIENTS OF THE AMBULATORY OF DM 1 OF UNIVERSITY HOSPITAL OF THE FEDERAL UNIVERSITY OF MARANHÃO (HUUFMA)
Maturity onset diabetes of young 3 (MODY 3)é o mais frequente diabetes mellitus (DM) monogênico autossômico dominante causado por mutações no gene HNF 1A e caracterizado por defeito na secreção de insulina, diminuição no limiar renal de glicose e sensibilidade a sulfonureia, na maioria das vezes. Com frequência é diagnosticado erroneamente como DM
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 16/03/2012
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10. Regressão prostática pós-castração : caracterização das alterações causadas pela privação androgênica e alta dose de 17ß- estradiol / Prostatic regression after castration : characterization of changes by androgen deprivation and high dose 17ß- estradiol
O desenvolvimento, a fisiologia e o câncer de próstata dependem de balanços entre os níveis de andrógenos e estrógenos, que agem via receptor de andrógenos (AR) e receptores de estrógeno (ER alfa e ER beta ), respectivamente. Sabe-se que a cinética de morte das células epiteliais da próstata ventral de ratos (PV) após castração (grupo Cas), adm
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 29/02/2012
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11. Variants of the HNF1α gene: a molecular approach concerning diabetic patients from southern Brazil
Maturity Onset Diabetes of the Young (MODY) presents monogenic inheritance and mutation factors which have already been identified in six different genes. Given the wide molecular variation present in the hepatocyte nuclear factor-1α gene (HNF1α) MODY3, the aimof this study was to amplify and sequence the coding regions of this gene in seven patients from
Genet. Mol. Biol.. Publicado em: 09/10/2012
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12. Comparação dos efeitos da heparina não fracionada e heparina de baixo peso molecular na cicatrização de feridas na pele de ratos
OBJETIVO: Comparar os efeitos da heparina não fracionada (HNF) e da heparina de baixo peso molecular (HBPM) na cicatrização de feridas cutâneas de ratos. MÉTODOS: Quarenta e oito ratos machos Sprague-Dawley foram submetidos à ferida na pele dorsal com espessura total de 8mm e foram distribuídos aleatoriamente em três grupos iguais. No grupo experimen
Acta Cirurgica Brasileira. Publicado em: 2012-09