Hfsh
Mostrando 1-9 de 9 artigos, teses e dissertações.
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1. HORMÔNIO FOLÍCULO ESTIMULANTE HUMANO (hFSH) E TIROXINA (T4) NA MANUTENÇÃO DA SOBREVIVÊNCIA E PROMOÇÃO DO CRESCIMENTO IN VITRO DE FOLÍCULOS PRÉ-ANTRAIS CAPRINOS
O objetivo deste estudo foi investigar a interação do FSH humano (10 ng/mL) com T4 (20 ng/mL) na sobrevivência, ativação e crescimento de folículos pré-antrais cultivados in vitro, por um período de longa duração (28 dias). Fragmentos de tecido ovariano não cultivado e cultivados foram processados para histologia clássica e microscopia eletrônic
Ciênc. anim. bras.. Publicado em: 2015-06
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2. ANALYSIS OF RECOMBINANT AND NATIVE HUMAN LUTROPIN AND HUMAN CHORIONIC GONADOTROPIN BY REVERSED-PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY / Análise de luteotrofina humana e de gonadotrofina coriônica humana, recombinante e natural, por cromatografia líquida de alta eficiência em fase reversa
Neste trabalho foram desenvolvidas condições específicas de RP-HPLC para análise de preparações recombinantes e naturais de hLH, de hCG, e de suas subunidades. O hLH e o hCG heterodimérico e suas subunidades e migraram com tempos de retenção (tR) significativamente diferentes, na seguinte ordem de hidrofobicidade crescente: -hCG <-hLH
Publicado em: 2009
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3. Preparação e caracterização das subunidades alfa e beta dos hormônios glicoproteicos humanos recombinantes: foliculotrofina, luteotrofina, tereotrofina e sua comparação com os produtos hipofisários / Preparation and characterization of alpha and beta subunits of recombinant human glycoprotein hormones: follicle-stimulating hormone, luteotropin, thyrotrophin and comparation with pituitary glycoprotein hormones
Neste trabalho é descrito um método prático e eficiente para dissociar, em subunidades α e β, quantidades pequenas (da ordem de microgramas) dos hormônios foliculotrofina (hFSH), luteotrofina (hLH) e tireotrofina (hTSH) humana, nativos e recombinantes. A dissociação destes hormônios foi conseguida incubando-os, durante 16 horas, a 37ºC, co
IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia. Publicado em: 23/10/2008
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4. Caracterização da expressão e função de receptores recombinantes do hormônio folículo-estimulante. / Characterization of expression and function of recombinant follicle-stimulating receptors.
The follicle stimulating hormone receptor (FSHR) is a member of a family of Gprotein-coupled receptors that has a large aminoterminal domain, rich in leucine repeats. The FSHR, together with the luteinizing hormone receptor, controls gonadal function in vertebrates. Mutations in the FSHR can alter its binding and signaling properties, and drastically affect
Publicado em: 2006
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5. Conversion of human choriogonadotropin into a follitropin by protein engineering.
Human reproduction is dependent upon the actions of follicle-stimulating hormone (hFSH), luteinizing hormone (hLH), and chorionic gonadotropin (hCG). While the alpha subunits of these heterodimeric proteins can be interchanged without effect on receptor-binding specificity, their beta subunits differ and direct hormone binding to either LH/CG or FSH receptor
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6. Recognition by the glycoprotein hormone-specific N-acetylgalactosaminetransferase is independent of hormone native conformation.
Some members of the glycoprotein hormone family [luteinizing hormone (LH), thyroid-stimulating hormone (TSH), and free alpha subunit] bear unique asparagine-linked oligosaccharides with the terminal sequence SO4-Gal-NAc beta 1,4GlcNAc beta 1,2Man alpha, whereas other members [human chorionic gonadotropin (hCG) and follicle-stimulating hormone (FSH)] bear pre
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7. Production rates and metabolic clearance rates of human follicle—stimulating hormone in premenopausal and postmenopausal women
The production rates (PR) and the metabolic clearance rates (MCR) of human follicle—stimulating hormone (HFSH) were determined in six pre- and five postmenopausal women. Human FSH (PER-780) labeled with 131I to specific activities of 50-150 μc/μg was used as a tracer. Both double antibody and trichloroacetic acid (TCA) precipitation techniques were used
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8. High-affinity and specific recognition of human thyroid stimulating hormone (hTSH) by in vitro-selected 2'-amino-modified RNA.
RNA sequences containing 2'-amino pyrimidines that bind with high-affinity to human thyroid stimulating hormone (hTSH) were isolated from a random sequence library by an in vitro selection-amplification procedure. A representative RNA ligand (T-15) has an equilibrium dissociation constant (Kd) of 2.5 nM for its interaction with hTSH and can discriminate betw
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9. Relative roles of follicle-stimulating hormone and luteinizing hormone in the control of inhibin secretion in normal men.
The glycoprotein hormone inhibin is produced by the Sertoli cells of the testis under the influence of follicle-stimulating hormone (FSH) and is postulated in turn to inhibit FSH secretion. Luteinizing hormone (LH) is not recognized to have an important role in the control of inhibin secretion in any species. To determine the relative roles of FSH and LH in