Heparins
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Análise do grau de recanalização da trombose venosa profunda: estudo comparativo de pacientes tratados com varfarina versus rivaroxabana
Resumo Contexto A trombose venosa profunda (TVP) afeta anualmente cerca de dez milhões de pessoas no mundo e tem como principais complicações a embolia pulmonar e a síndrome pós-trombótica. O tratamento padrão é a anticoagulação, que pode ser realizada com heparinas, antagonistas da vitamina K, fondaparinux ou, mais recentemente, com anticoagulant
J. vasc. bras.. Publicado em: 27/06/2019
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2. Evidências farmacológico-clínicas para uso das heparinas de baixo peso molecular nas síndromes coronarianas agudas / Pharmacological and clinical evidence for the use of low-molecular-weight heparins in acute coronary syndromes
Publicado em: 2010
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3. Ação de polissacarídeos sulfatados de Fucus Vesiculosus na Hemostasia e no sistema complemento
Fucans are a family of sulfated homo and teropolysaccharides respectively, composed mainly of a- (12) and a- (13) linked by L-fucose residues. Properties such as the ability to act as an anti-contraceptive, to reduce cholesterol levels, and to act as an anti-tumor agent are much related. We have focused our attention on the anticoagulant properties, platelet
Publicado em: 2006
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4. ViabilizaÃÃo da heparina como suporte para carrear gentamicina
Many polymers used as drug carriers in controlled delivery systems are polysaccharides. This work propose the use of glycosaminoglycan heparin as carrier for the aminoglycosidic antibiotic gentamicin. Due to their chemical feature, these compounds possess an intrinsic ionic affinity, nevertheless, a carbodiimide was used to promote covalent binding (amide bo
Publicado em: 2002
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5. Pharmacological and clinical evidence for the use of low-molecular-weight heparins in acute coronary syndromes
Arquivos Brasileiros de Cardiologia. Publicado em: 2001-08
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6. Development of new heparin-like compounds and other antithrombotic drugs and their interaction with vascular endothelial cells
The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly reviewed. Heparin isolated from shrimp mimics the pharmacological activities of low molecular weight heparins. A heparan sulfate from Arte
Brazilian Journal of Medical and Biological Research. Publicado em: 2001-06
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7. Suppression of experimental autoimmune diseases and prolongation of allograft survival by treatment of animals with low doses of heparins.
The ability of activated T lymphocytes to penetrate the extracellular matrix and migrate to target tissues was found to be related to expression of a heparanase enzyme (Naparstek, Y., I. R. Cohen, Z. Fuks, and I. Vlodavsky. 1984. Nature (Lond.). 310:241-243; Savion, N., Z. Fuks, and I. Vlodavsky. 1984. J. Cell. Physiol. 118:169-176; Fridman, R., O. Lider, Y.
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8. Hepatic uptake of a modified low molecular weight heparin in rats.
Fractionated and unfractionated heparins are widely used as antithrombotic agents. Because of their heterogeneous composition, it is difficult to study the pharmacokinetics of these drugs. We now report on a new method for labeling low molecular weight heparins with 131I by binding tyramine to the anhydromannose end of the molecules. We examined the pharmaco
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9. Low-Molecular-Weight Heparins in the Cardiac Catheterization Laboratory
We describe the unique properties of low-molecular-weight heparins and review studies of the use of these agents in the catheterization laboratory for percutaneous coronary intervention. Recent data regarding bedside monitoring of low-molecular-weight heparin activity are also discussed, as are ongoing and future studies that should be of assistance to clini
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10. Interaction of Heparins and Dextran Sulfates with a Mesoscopic Protein Nanopore
A mechanism of how polyanions influence the channel formed by Staphylococcus aureus α-hemolysin is described. We demonstrate that the probability of several types of polyanions to block the ion channel depends on the presence of divalent cations and the polyanion molecular weight and concentration. For heparins, a 10-fold increase in molecular weight decrea
The Biophysical Society.
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11. New advances in the management of acute coronary syndromes: 4. Low-molecular-weight heparins
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12. Growth-Inhibitory Effect of Heparin on Babesia Parasites
We examined the inhibitory effects of three heparins on the growth of Babesia parasites. The multiplication of Babesia bovis, B. bigemina, B. equi, and B. caballi in in vitro cultures and that of B. microti in vivo were significantly inhibited in the presence of heparins, as determined by light microscopy. Treatment with various concentrations of heparin sho
American Society for Microbiology.