Hematological Malignancies
Mostrando 1-12 de 58 artigos, teses e dissertações.
-
1. Expansion of cord blood stem cells in fibronectin-coated microfluidic bioreactor
ABSTRACT Background: Hematopoietic stem/progenitor cell transplantation is the main treatment option for hematological malignancies and disorders. One strategy to solve the problem of low stem cell doses used in transplantation is pre-transplant expansion. We hypothesized that using fibronectin-coated microfluidic channels would expand HSPCs and keep self-r
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
-
2. The relationship between red cell distribution width and prognostic scores in myelodysplastic syndrome
ABSTRACT Introduction: The myelodysplastic syndrome (MDS) represents a group of hematopoietic neoplasms that is characterized by clonal hematopoiesis, cytopenia and abnormal cellular maturation. Red cell distribution width (RDW) refers to the variation degree of erythrocyte size and it is a reflection of anisocytosis. Higher values have been linked to adver
Hematology, Transfusion and Cell Therapy. Publicado em: 2022
-
3. An exceptional case report of disseminated cryptococcosis in a hitherto immunocompetent patient
ABSTRACT Cryptococcosis is an opportunistic fungal infection causes significant disease predominantly in immunocompromised patients. Here we present an excepcional case of disseminated cryptococcosis with pulmonary and cerebral involvement in an immunocompetent patient with no apparent predisposing factors at the time of hospital admission. We described a ca
Rev. Inst. Med. trop. S. Paulo. Publicado em: 17/01/2020
-
4. Differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis
Abstract Our objective was to determine the association between the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) and the risk of developing acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), acute myeloid leukemia (AML), and multiple myelomas (MM) in Latinos. PubMed, SCOPUS, EBSCO, LILACS, and other Latin-specific dat
Genet. Mol. Biol.. Publicado em: 14/11/2019
-
5. Incidência e risco de quedas em pacientes tratados por neoplasias hematológicas na Unidade de Hematologia Intensiva
Objetivo: determinar a incidência e a taxa de risco de quedas em pacientes adultos tratados por neoplasias hematológicas na Unidade de Hematologia Intensiva de um hospital de referência. Método: corresponde a um estudo observacional retrospectivo. Foram avaliados 101 pacientes. A ocorrência de quedas foi obtida a partir do registro da unidade e as var
Rev. Latino-Am. Enfermagem. Publicado em: 29/04/2019
-
6. Assessing the impact of ABO incompatibility on major allogeneic hematopoietic stem cell transplant outcomes: a prospective, single-center, cohort study
Abstract Background ABO blood group incompatibility between donor and recipient is associated with a number of immunohematological complications, but is not considered a major contraindication to allogeneic hematopoietic stem cell transplantation. However, available evidence from the literature seems to be conflicting as to the impact of incompatibility on
Hematol., Transfus. Cell Ther.. Publicado em: 15/04/2019
-
7. Philadelphia-negative myeloproliferative neoplasms as disorders marked by cytokine modulation
ABSTRACT Background: Cytokines are key immune mediators in physiological and disease processes, whose increased levels have been associated with the physiopathology of hematopoietic malignancies, such as myeloproliferative neoplasms. Methods: This study examined the plasma cytokine profiles of patients with essential thrombocythemia, primary myelofibrosis,
Hematol., Transfus. Cell Ther.. Publicado em: 2018-06
-
8. Bullous pyoderma gangrenosum as a predictor of hematological malignancies
Abstract: Pyoderma gangrenosum may precede, coexist or follow diverse systemic diseases. The bullous variety is usually associated with hematologic disorders. From 31 patients with pyoderma gangrenosum diagnosed in our hospital during 10 years, only 2 presented with the bullous type. One patient had previous diagnosis of chronic myeloid leukemia. Both had fa
An. Bras. Dermatol.. Publicado em: 2018-02
-
9. Galactomannan use in clinical practice: providing free testing is not the full answer
ABSTRACT Introduction: Invasive aspergillosis is a condition associated with a high mortality rate mostly due to difficulties in performing an early diagnosis. In recent years, galactomannan detection has markedly improved the diagnosis of invasive aspergillosis, but very little is known on how physicians deal with this test in clinical practice. Methods:
Braz J Infect Dis. Publicado em: 2018-01
-
10. Invasive fungal infection in patients with hematologic disorders in a Brazilian tertiary care hospital
ABSTRACT INTRODUCTION: Invasive fungal infections (IFIs) are an important complication in immunocompromised individuals, particularly neutropenic patients with hematological malignancies. In this study, we aimed to verify the epidemiology and diagnosis of IFIs in patients with hematologic problems at a tertiary hospital in Goiânia-GO, Brazil. METHODS: D
Rev. Soc. Bras. Med. Trop.. Publicado em: 2017-02
-
11. The importance of risk factors for the prediction of patients with invasive pulmonary aspergillosis
Summary Objective: Invasive pulmonary aspergillosis (IPA) is a major challenge in the management of immunocompromised patients. Despite all the advances in diagnosis, it remains a problem. The purpose of our study was to investigate the risk factors associated with IPA seen in patients with hematological malignancies. Method: A total of 152 febrile neutrop
Rev. Assoc. Med. Bras.. Publicado em: 2017
-
12. Invasive infection due to Saprochaete capitata in a young patient with hematological malignancies
We report a case of invasive infection due to Saprochaete capitata in a patient with hematological malignancies after chemotherapy treatment and empiric antifungal therapy with caspofungin. Although severely immunocompromised the patient survived been treated with amphotericin B lipid complex associated with voriconazole.
Braz. J. Microbiol.. Publicado em: 2015-06