Granules Coating
Mostrando 1-12 de 24 artigos, teses e dissertações.
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1. Design and evaluation of rhubarb total free anthraquinones oral colon-specific drug delivery granules to improve the purgative effect
Rhubarb is commonly used as a cathartic in Asian countries. However, researchers have devotedextensive concerns to the quality control and safety of rhubarb and traditional Chinese preparations composed of rhubarb due to the instable purgative effect and potential nephrotoxicity of anthraquinones. In this study, we aimed to prepare rhubarb total free anthraq
Braz. J. Pharm. Sci.. Publicado em: 10/07/2019
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2. Biodegradable oil-based polymeric coatings on urea fertilizer: N release kinetic transformations of urea in soil
ABSTRACT: Polymer coatings are used to control the rate of release of plant available nutrients from fertilizers as well as to reduce nutrient losses such as ammonia (NH3) volatilization. Although the literature presents several examples of materials used to coat urea, little is known about nitrogen (N) release properties such as the mechanism involved and p
Sci. agric. (Piracicaba, Braz.). Publicado em: 01/07/2019
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3. Coating of urea granules by in situ polymerization in fluidized bed reactors
Abstract The main objective of the present work is to produce and characterize urea granules coated with polymers prepared with aqueous solutions of acrylic acid and glycerol. Both coating and drying of urea granules were performed in a fluidized bed reactor. Fourier transform infrared spectroscopy analyses indicated the presence of poly(acrylic acid) and ac
Polímeros. Publicado em: 21/03/2019
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4. Evaluation of the solubility of the HPMC: PVA blends in biological fluids in vitro
Polymers are often used to coat tablets for controlled drug release. The purpose of this study is to evaluate the solubility of the HPMC and PVA blend compared to isolated polymers in solutions with a pH of biological fluids (6 and 1.2) and the dissolution of capsules obtained using theophylline granules produced with the HPMC/PVA 25/75 blend as a matrix and
Materials Research. Publicado em: 27/05/2011
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5. Obtenção de sistemas multiparticulados de isoniazida revestidos com polímero de liberação entérica
Known for thousands of years, tuberculosis (TB) is the leading cause of mortality by a single infectious disease due to lack of patient adherence to available treatment regimens, the rising of multidrug resistant strains of TB (MDR-TB) and co-infection with HIV virus. Isoniazid and rifampicin are the most powerful bactericidal agents against M. tuberculosis.
Publicado em: 2009
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6. Morphology of the alimentary canal of the gecko Hemidactylus mabouia (Moreau de Jonnès, 1818) (Squamata: Gekkonidae) / Morfologia do tubo digestivo da lagartixa Hemidactylus mabouia (Moreau de Jonnès, 1818) (Squamata: Gekkonidae).
Hemidactylus mabouia is the gecko species more thoroughly distributed in Brazil, being common in anthropic atmospheres, what turns easy its use as model for study of the reptiles. Likewise, aiming at to describe morphologically the alimentary canal of H. mabouia, 17 adult specimens were used, being collected fragments of the esophagus, of the oesophagogastri
Publicado em: 2009
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7. Polymeric coating and pharmacokinetic of chitosan granules containing ddI incorporated in microparticles / Revestimento polimerico e farmacocinetica de granulos gastrorresistentes contendo didanosina incorporada em microparticulas de quitosana
This work studied the production and pharmacokinetic of a new pharmaceutical formulation of the didanosine (ddI) drug ,composed by chitosan granules containing ddI incorporated in microparticles, for oral administration in the AIDS therapy. The advantages of this new pharmaceutical formulation compared to the conventional one are: to assure ddI stability in
Publicado em: 2008
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8. Fluidized bed coating of pharmaceutical granules. / Revestimento de grânulos farmacêuticos em leito fluidizado
Operações de revestimento são amplamente utilizadas em diversos setores industriais, tais como químico, agrícola, alimentício e farmacêutico. Dentre as principais razões para a aplicação de revestimento em partículas destacam-se fatores estéticos, proteção e o controle da taxa de dissolução de substâncias químicas. Este trabalho teve por ob
Publicado em: 2007
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9. Desenvolvimento e avaliação tecnológica de granulado revestido contendo produto seco por spray drying de achyrocline satureioides (Lam.) D.C. asteraceae (marcela) / Development and technological evaluation of coating granules containing spray dried extract of Achyrocline satureioides (Lam.) DC. Asteraceae (Marcela)
O presente trabalho refere-se ao desenvolvimento de grânulos a partir de produto seco de A. satureioides obtido por spray drying, em escala semi-industrial, visando a superar as principais limitações tecnológicas apresentadas tais como a higroscopia excessiva do produto, baixa densidade, pequeno tamanho de partícula e instabilidade dos constituintes fla
Publicado em: 2007
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10. Microparticulas de quitosana com didanosina e sua formulação em granulos mucoadesivos / Didanosine-load chitosan microspheres and their formulation in mucoadhesive granules
In this work a scalable process was developed for the production of gastroresistent granules containing chitosan microspheres, loaded with the drug didanosine (ddl). The global process included three stages, and the operational conditions were optimized in order to maintain the active form of the drug didanosine, which is sensitive to acidic pH conditions, a
Publicado em: 2006
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11. Caracterização fluidodinamica no recobrimento de celulose microcristalina em leito fluidizado
The coating of granular materials is an operation widely used by tbe Pharrnaceutical industry with diverse purposes: to improve the product appearance, to obtain a product with controlled release of active components, to facilitate the administration through the artainrnent of a smooth surface, to identii)r the drug by colors, to prateet the drug ITom atmosp
Publicado em: 2004
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12. Actin coating of secretory granules during regulated exocytosis correlates with the release of rab3D
The present study describes a novel phenomenon in pancreatic acinar cells undergoing regulated exocytosis. When acinar cell preparations were challenged with the secretagogue carbamylcholine, a subpopulation of zymogen granules became coated with filamentous actin. These zymogen granules were always in proximity of the acinar cell apical membrane (the site o
The National Academy of Sciences.