Genetic Models
Mostrando 1-12 de 1160 artigos, teses e dissertações.
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1. Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis
Objective: Individuals with schizophrenia and substance use disorders have a poor prognosis and increased psychiatric symptoms. The present study aimed to explore the association of 106 genes in individuals with schizophrenia and comorbid substance use through a next-generation sequencing (NGS) analysis and different in silico algorithms. Methods: We includ
Brazilian Journal of Psychiatry. Publicado em: 2022
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2. Possible association between a polymorphism of EPAS1 gene and persistent pulmonary hypertension of the newborn: a case-control study
Abstract Objective: To explore possible genes related to the development of persistent pulmonary hypertension of the newborn (PPHN). Methods: The authors identified 285 single nucleotide polymorphisms (SNPs) of 11 candidate genes (BMPR2, EPAS1, PDE3A, VEGFA, ENG, NOTCH3, SOD3, CPS1, ABCA3, ACVRL1, and SMAD9), using an Illumina Asian Screening Array-24 v1.0
Jornal de Pediatria. Publicado em: 2022
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3. DD Genotype and Atherosclerosis in Overweight Menopausal Women
Abstract Background Sex-specific pathology of coronary artery disease (CAD) has not been recognized. Women with obstructive or nonobstructive CAD associated with traditional risk factors have similar events; no studies have explored both populations in association with genetic markers. Objective To evaluate the DD genotype in overweight menopausal women
Int. J. Cardiovasc. Sci.. Publicado em: 2021-08
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4. A antropologia e as crianças: da consolidação de um campo de estudos aos seus desdobramentos contemporâneos
Abstract Background Sex-specific pathology of coronary artery disease (CAD) has not been recognized. Women with obstructive or nonobstructive CAD associated with traditional risk factors have similar events; no studies have explored both populations in association with genetic markers. Objective To evaluate the DD genotype in overweight menopausal women
Horiz. antropol.. Publicado em: 2021-08
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5. IL-4-C-590T locus polymorphism and susceptibility to asthma in children: a meta-analysis
Abstract Objectives The study aimed to evaluate the link between the IL-4-C590T polymorphism and asthma susceptibility in children by meta-analysis. Sources The study collected all the case-control studies found in PubMed, Embase, CNKI, Wanfang, VIP, and other databases until September 2019. Stata v. 15.0 was used to conduct meta-analysis, calculate the co
J. Pediatr. (Rio J.). Publicado em: 2021-06
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6. Quantifying individual variation in reaction norms using random regression models fitted through Legendre polynomials: application in eucalyptus breeding
ABSTRACT An accurate, efficient and informative statistical method for analyses of genotype × environment (G × E) interactions is a key requirement for progress in any breeding program. Thus, the objective of this study was to quantify individual variation in reaction norms using random regression models fitted through Legendre polynomials in eucalyptus (E
Bragantia. Publicado em: 2020-12
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7. A new proposal for the m + a methodology in segregating populations of cowpea
ABSTRACT The evaluation of segregating populations in plant breeding programs is an onerous and time-consuming process. Early identification of populations with genetic potential can be done by m + a methodology. However, the possibility of a modification in the traditional methodology in order to make it more efficient, that is, faster and cheaper, was envi
Bragantia. Publicado em: 2020-06
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8. The rs11755527 polymorphism in the BACH2 gene and type 1 diabetes mellitus: case control study in a Brazilian population
ABSTRACT Objective Type 1 diabetes mellitus (T1DM) is an autoimmune disorder caused by a complex interaction between environmental and genetic risk factors. BTB domain and CNC homolog 2 (BACH2) gene encodes a transcription factor that acts on the differentiation and formation of B and T lymphocytes. BACH2 is also involved in the suppression of apoptosis an
Arch. Endocrinol. Metab.. Publicado em: 2020-04
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9. Selection of high-yielding, adapted and stable wheat lines in preliminary trials
Abstract Experimental design without replication, such as Federer's augmented block design, allows us to determine productivity, adaptability and stability in multi-environment trials. This work aimed to select productive wheat lines with high adaptability and stability in preliminary trials. The grain yield of 140 homozygous wheat lines was measured in 2015
Crop Breed. Appl. Biotechnol.. Publicado em: 05/12/2019
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10. Performance and Egg Quality of Commercial Laying Hens Fed Diets Formulated Using Non-Linear Programming
ABSTRACT Feed formulation using linear programming consists of determining the mixture of feedstuffs required to meet pre-established animal nutritional requirements at the lowest cost. On the other hand, with the use of non-linear programming, it is possible to define nutritional requirements at the time of formulation, aiming at maximum profit. The objecti
Braz. J. Poult. Sci.. Publicado em: 25/11/2019
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11. Differential effects of the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) on hematological malignancies among Latinos: a meta-analysis
Abstract Our objective was to determine the association between the methylenetetrahydrofolate reductase polymorphisms (C677T and A1298C) and the risk of developing acute lymphoblastic leukemia (ALL), chronic myeloid leukemia (CML), acute myeloid leukemia (AML), and multiple myelomas (MM) in Latinos. PubMed, SCOPUS, EBSCO, LILACS, and other Latin-specific dat
Genet. Mol. Biol.. Publicado em: 14/11/2019
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12. Resistance of the wild tomato Solanum habrochaites to Phytophthora infestans is governed by a major gene and polygenes
Abstract: This work aimed to study the inheritance of resistance to Phytophthora infestans in tomato plants, using the maximum likelihood estimation function. The susceptible cultivar Santa Clara (Solanum lycopersicum) was used as the female genitor and the P. infestans resistant S. habrochaites f. glabratum accession (BGH 6902) as the male genitor. F1 plant
An. Acad. Bras. Ciênc.. Publicado em: 11/11/2019