Gene Qm
Mostrando 1-12 de 21 artigos, teses e dissertações.
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1. Prevalência da mutação causadora da paralisia periódica hipercalêmica em equinos da raça Quarto de Milha no Brasil
A paralisia periódica hipercalêmica (HYPP) é uma das principais enfermidades genéticas de caráter dominante que acometem cavalos da raça Quarto de milha (QM). A HYPP é causada por uma mutação pontual no gene SCN4A e, apesar de estar presente nos cavalos QM no Brasil, dados sobre a prevalência da HYPP são escassos. O objetivo deste trabalho foi ver
Cienc. Rural. Publicado em: 2015-05
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2. Characterization of the RNA Polymerase B Transcricional Factor 3 (btf3) of Trichoderma reesei and the effect of its knockout on gene expression in stress by heat shock / Caracterização do gene do Fator Transcricional 3 da RNA Polimerase B (btf3) de Trichoderma reesei e o efeito de seu nocaute sobre a expressão gênica no estresse por choque térmico
Transcription by RNA polymerase II (RNA polymerase B) and protein synthesis are the most important metabolic processes in eukaryotic cells, and they are involved in the control of gene expression. Trichoderma reesei was used as model of study for the development of this study. This filamentous fungus is a microorganism that has been used by some laboratories
Publicado em: 2007
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3. O espectro das falências ovarianas ligadas ao cromossomo X
A falência ovariana manifesta-se clinicamente por amenorréia primária ou secundária, e do ponto de vista hormonal caracteriza-se pelos níveis elevados de gonadotrofinas hipofisárias, principalmente FSH, cuja etiologia pode ser atribuída a varias causas, como redução numérica ou rearranjos do cromossomo X, entre outras. Além da síndrome de Turner
Arquivos Brasileiros de Endocrinologia & Metabologia. Publicado em: 2001-08
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4. Gene Transduction and Cell Entry Pathway of Fiber-Modified Adenovirus Type 5 Vectors Carrying Novel Endocytic Peptide Ligands Selected on Human Tracheal Glandular Cells
Monolayers of cystic fibrosis transmembrane conductance regulator (CFTR)-deficient human tracheal glandular cells (CF-KM4) were subjected to phage biopanning, and cell-internalized phages were isolated and sequenced, in order to identify CF-KM4-specific peptide ligands that would confer upon adenovirus type 5 (Ad5) vector a novel cell target specificity and/
American Society for Microbiology.
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5. Isolation and characterization of the QM promoter.
This report describes the isolation, sequencing and preliminary characterization of the first 1 kb of the 5'-regulatory region of the human QM gene. This region and the 5' -half of the transcribed region of the QM gene are enriched for C and G nucleotides with no bias against CpG dinucleotides--indicative of a CpG island. Several consensus GC boxes are prese
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6. Genetics of leucine biosynthesis in Bacillus megaterium QM B1551.
Genes involved in the biosynthesis of leucine have been mapped in Bacillus megaterium QM B1551, using transducing phage MP13. Mutations were designated leuA, leuB, or leuC on the basis of enzyme assays. Two mutant strains were deficient in the enzyme activities of leuA (alpha-isopropylmalate synthase) and leuC (beta-isopropylmalate dehydrogenase) and so may
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7. Molecular Characterization and Heterologous Expression of the Gene Encoding a Low-Molecular-Mass Endoglucanase from Trichoderma reesei QM9414
We have isolated the genomic and cDNA clones encoding EG III (a low-molecular-mass endo-β-1,4-glucanase) gene from Trichoderma reesei QM9414. The nucleotide sequence of the cDNA fragment was verified to contain a 702-bp open reading frame that encodes a 234-amino-acid propeptide. The deduced protein sequence has significant homologies with family H endo-β-
American Society for Microbiology.
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8. Sensitive and Efficient Detection of RB1 Gene Mutations Enhances Care for Families with Retinoblastoma
Timely molecular diagnosis of RB1 mutations enables earlier treatment, lower risk, and better health outcomes for patients with retinoblastoma; empowers families to make informed family-planning decisions; and costs less than conventional surveillance. However, complexity has hindered clinical implementation of molecular diagnosis. The majority of RB1 mutati
The American Society of Human Genetics.
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9. A Jun-binding protein related to a putative tumor suppressor.
A lambda gt11 cDNA library of chicken embryo fibroblasts was screened with biotinylated Jun protein to identify Jun-binding clones. Eight such clones were isolated; one contains a gene referred to as jif-1 that is homologous to the putative tumor suppressor gene QM. jif-1 codes for a protein of 25 kDa that binds to the leucine zipper of viral and cellular Ju
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10. Regulation of expression of the ftsA cell division gene by sequences in upstream genes.
The essential cell division genes ftsQ and ftsA overlap by 1 bp (A. C. Robinson, D. J. Kenan, G. F. Hatfull, N. F. Sullivan, R. Spiegelberg, and W. D. Donachie. J. Bacteriol. 160:546-555, 1984; Q.-M. Yi, S. Rockenbach, J. E. Ward, and J. F. Lutkenhaus. J. Mol. Biol. 184:399-412, 1985). We have previously shown that ftsA can be expressed from a weak promoter
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11. Structure and function in rhodopsin: A tetracycline-inducible system in stable mammalian cell lines for high-level expression of opsin mutants
Tetracycline-inducible HEK293S stable cell lines have been prepared that express high levels (up to 10 mg/liter) of WT opsin and its mutants only in response to the addition of tetracycline and sodium butyrate. The cell lines were prepared by stable transfection of HEK293S-TetR cells with expression plasmids that contained the opsin gene downstream of a cyto
The National Academy of Sciences.
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12. Identification of fragments of human transcripts froma defined chromosomal region: representational difference analysis of somatic cell hybrids.
We have tested representational difference analysis of cDNAs from somatic cell hybrids as a means to directly isolate expressed sequences derived from a defined chromosomal region. To this end, the hamster-human somatic cell hybrid Q1Z, which carries Xq28 as the only human chromosomal fragment, was used as Tester and the parental hamster cell line Y21 as Dri