Gene Nuc
Mostrando 13-24 de 66 artigos, teses e dissertações.
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13. Investigação clínica e genética em meninas com baixa estatura idiopática
Em 10 meninas com diagnóstico de baixa estatura idiopática (BEI), realizamos avaliação citogenética após revisão clínica. Dois cariótipos foram anormais: mos 45,X/46,XX; mos 45,X/46,X,der(Xp)/46,X,r(X), e para sua elucidação foram aplicadas técnicas de citogenética molecular e análise de microssatélites, incluindo SHOX CA repeat. Os resultados
Arquivos Brasileiros de Endocrinologia & Metabologia. Publicado em: 2003-12
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14. Identificação de Staphylococcus aureus, S. intermedius e S. hyicus através de seqüências dos genes coa e nuc
Sessenta e cinco cepas de estafilococos coagulase positiva foram identificadas em nível de espécie, através da amplificação, por PCR, de seqüências do gene coa, específicas para S. aureus, e do gene nuc, específicas para S. intermedius e para S. hyicus.
Brazilian Journal of Microbiology. Publicado em: 2003-11
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15. Regulação da expressão e ativação do fator de transcrição C-JUN no miocardio de ratos submetido a sobrecarga pressora aguda
The early expression of immediate early genes is a fundamental feature of myocardial hypertrophy. The immediate early gene c-jun codifies a transcription factor that has been assigned to be an important regulator of the hypertrophic response in cardiac myocytes. In the present study we investigated whether pressure overload or phenylephrine treatment stimula
Publicado em: 2003
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16. Estudo de mutações no gene GJB3 como causa de deficiencia auditiva neurossensorial não-sindromica
Deafness is one of the most common sensory defects in the general population and its prevalence increases with age. In developed countries about 60% of hearing loss cases are due to genetic factors. In Brazil the majority of cases of hearing loss are due to environmental factors. However, the proportion of genetic causes tends to increase as a result of impr
Publicado em: 2003
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17. A síntese da fosfatase alcalina Pi-repressível não parece ser regulada pelo pH ambiente no fungo filamentoso Neurospora crassa
Para investigar a resposta adaptativa ao pH ambiente em fungos, foram determinados por ELISA os níveis de fosfatase alcalina Pi-repressível expressada pelo gene pho-2 de Neurospora crassa. Foi mostrado que as linhagens 74A e pho-2A deste fungo secretam quantidades semelhantes da fosfatase alcalina Pi-repressível independentemente do pH ambiente, quando am
Brazilian Journal of Microbiology. Publicado em: 2002-01
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18. Analise da variação intra-especifica em linhagens brasileiras de Schistosoma mansoni (Sambon, 1907) atraves de RAPD-PCR e RAP-PCR
Resumo: Variações fenotípicas intra e inter-populacionais de Schistosoma mansoni ocorrem em várias áreas geográficas. A heterogeneidade genética do parasita contribui para a observada variação fenotípica na interação parasita-hospedeiro, desempenhando um importante papel na epidemiologia da doença. A diferença fenotípica mais estudada, no enta
Publicado em: 2001
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19. Molecular analysis of nuc-1+, a gene controlling phosphorus acquisition in Neurospora crassa.
In response to phosphorus starvation, Neurospora crassa makes several enzymes that are undetectable or barely detectable in phosphate-sufficient cultures. The nuc-1+ gene, whose product regulates the synthesis of these enzymes, was cloned and sequenced. The nuc-1+ gene encodes a protein of 824 amino acids with a predicted molecular weight of 87,429. The amin
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20. The structural gene for a phosphorus-repressible phosphate permease in Neurospora crassa can complement a mutation in positive regulatory gene nuc-1.
van+, a gene encoding a phosphorus-repressible phosphate permease, was isolated by its ability to complement nuc-1, a positive regulatory locus that normally regulates van+ expression. This was unexpected because the nuc-1 host already contained a resident van+ gene. Plasmids carrying van+ complemented a nuc-2 mutation as well. Probing of RNA from untransfor
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21. Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae.
The DNA sequence and studies on the expression of the NUC1 gene from Saccharomyces cerevisiae are presented. The NUC1 locus is located in the distal portion of the left arm of Chromosome X and encodes the major nuclease found in mitochondria. The inferred amino acid sequence of NUC1 predicts that the nuclease is basic, rich in prolines, of average hydrophobi
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22. The Serratia marcescens NucE protein functions as a holin in Escherichia coli.
The recently discovered nucC locus of Serratia marcescens encodes the cryptic prophage genes nucE, nucD, and nucC. NucC is required for expression of the S. marcescens nuclease and functions as a transcriptional activator of the nuclease gene, nucA. NucE and NucD are dispensable for nuclease expression but were proposed to allow for secretion of the nuclease
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23. Properties of Two Nuclease Genes in NEUROSPORA CRASSA
Two genes, nuc-1 and nuc-2, of Neurospora crassa which were responsible for the nucleic acid digestion, were located on linkage group 1 and 2, respectively. A temperature-sensitive mutant (B1ts-2) was obtained from a nuc-2 mutant. Nuclease mutants showed a reduced activity of nuclease N3 which was found to be a complex consisting of nuclease N3' and inhibito
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24. Yeast RNC1 encodes a chimeric protein, RhoNUC, with a human rho motif and deoxyribonuclease activity.
The yeast Saccharomyces cerevisiae contains an endoexonuclease yNucR that has been implicated in both recombination and repair. We describe the isolation and characterization of the corresponding gene. Within the predicted N-terminal half of the protein there is extensive homology (approximately 50%) with human rho genes, which are related to the ras oncogen