Gastrinoma
Mostrando 1-12 de 16 artigos, teses e dissertações.
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1. Gastrinoma pancreático maligno em lobo-guará (Chrysocyon brachyurus): relato de caso
RESUMO Uma fêmea lobo-guará de cativeiro (Chrysocyon brachyurus), diagnosticada previamente com leishmaniose visceral, desenvolveu miíase grave na orelha direita, seguida por prostação e morte. Um nódulo sólido, firme e medindo 1 x 3cm, foi macroscopicamente observado no pâncreas. Histologicamente, observou-se proliferação neoplásica no pâncreas
Arq. Bras. Med. Vet. Zootec.. Publicado em: 2018-03
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2. Surgical treatment of pancreatic endocrine tumors in multiple endocrine neoplasia type 1
Surgical approaches to pancreatic endocrine tumors associated with multiple endocrine neoplasia type 1 may differ greatly from those applied to sporadic pancreatic endocrine tumors. Presurgical diagnosis of multiple endocrine neoplasia type 1 is therefore crucial to plan a proper intervention. Of note, hyperparathyroidism/multiple endocrine neoplasia type 1
Clinics. Publicado em: 2012
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3. Gastrinoma primáro de fígado
Gastrinomas are generally localized in pancreas, duodenum and lymphonodes, within the so called "gastrinoma's triangle" . In 5% of the cases, it may arise from liver, stomach, ovarium, kidneys, parathyroid, omentum, jejunum and heart. We describe a case of a fifteen-year-old boy with a primary gastrinoma of the liver, treated by right-hepatectomy.
Revista do Colégio Brasileiro de Cirurgiões. Publicado em: 2003-08
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4. Apudomas pancreáticos: um desafio para clínicos e cirurgiões
OBJETIVO: O propósito do presente estudo é analisar as dificuldades quanto ao diagnóstico, avaliação prognóstica e conduta em sete pacientes portadores de tumores neuroendócrinos do pâncreas (apudomas), estudados na última década, comparando os resultados com aqueles discutidos na literatura. MÉTODO: A idade dos pacientes variou de 15 a 66 anos, c
Revista do Colégio Brasileiro de Cirurgiões. Publicado em: 2002-02
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5. Surgery in Zollinger-Ellison syndrome alters the natural history of gastrinoma.
OBJECTIVE: The authors assessed the impact of gastrinoma resection on the subsequent development of hepatic metastases in Zollinger-Ellison syndrome. SUMMARY BACKGROUND DATA: The symptoms of acid hypersecretion can be controlled medically in Zollinger-Ellison syndrome with high-dose pharmacologic therapy. The current role of surgery is curative excision of t
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6. Forty-year appraisal of gastrinoma. Back to the future.
OBJECTIVE: The author analyzed potential survival determinants in gastrinoma to characterize a possible uniform staging system and to determine whether complete surgical resection improves expected survival. SUMMARY AND BACKGROUND DATA: Gastrinoma is an indolent yet malignant neuroendocrine tumor. The associated gastric acid hypersecretion can be controlled
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7. Aggressive resection of metastatic disease in selected patients with malignant gastrinoma.
Fifteen patients with Zollinger-Ellison syndrome followed at the National Institutes of Health with extensive metastatic disease had an actuarial 5-year survival of 20%. Therefore, in 1982 a prospective study to examine the effect and feasibility of removing all gross tumor in selected patients with extensive metastatic disease was instituted. Five patients
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8. Prospective study of gastrinoma localization and resection in patients with Zollinger-Ellison syndrome.
In 1982, a prospective study was initiated of 52 consecutive patients with proven Zollinger-Ellison syndrome (ZES), involving surgical exploration with the goal of removing the gastrinoma after an extensive protocol to localize the tumor. Each patient underwent ultrasound, computed tomography (CT) with oral/intravenous (IV) contrast, and selective arteriogra
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9. Gastrinomas demonstrate amplification of the HER-2/neu proto-oncogene.
OBJECTIVE: This study determined whether genomic amplification of HER-2/neu or mutations of the p53 and ras genes were present in gastrinomas. SUMMARY BACKGROUND DATA: Amplification of HER-2/neu, a proto-oncogene related to the epidermal growth factor receptor, and mutation of the ras proto-oncogene and p53 tumor suppressor gene appear to play a role in the
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10. Molecular cloning of human gastrin cDNA: evidence for evolution of gastrin by gene duplication.
An oligo(dT)-primed cDNA copy of the mRNA coding for the human gastrin precursor was constructed from poly(A)-containing RNA from a human pancreatic, gastrin-producing tumor (a gastrinoma). The cDNA was inserted into the Pst I endonuclease site of plasmid pBR322 by the use of the poly(dC) and poly(dG) tailing procedure. Clones containing gastrin sequences we
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11. Removal of gastrinomas for control of Zollinger-Ellison syndrome.
There are two distinct problems in patients with Zollinger-Ellison Syndrome (ZES): peptic ulcer diathesis and malignant tumors. Antisecretory drugs have allowed us to control the ulcer symptoms and acid output in 45 patients with ZES. We report here the initial seven patients selected for surgical exploration with the goal of removing their gastrinomas. Prio
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12. Curative resection in Zollinger-Ellison syndrome. Results of a 10-year prospective study.
Since 1980, 73 patients with Zollinger-Ellison syndrome (ZES) without radiographic evidence of liver metastases were studied on a prospective protocol including medical management of gastric acid hypersecretion, extensive radiographic tumor localization, and exploratory surgery to find and resect gastrinoma for potential cure. Each patient had gastric acid h